8CT9

CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-distal state

This is a non-PDB format compatible entry.

Summary for 8CT9

• Entry DOI: 10.2210/pdb8ct9/pdb
• EMDB information: 26984
• Descriptor: Dynamin-like 120 kDa protein, mitochondrial, CARDIOLIPIN (2 entities in total)
• Functional Keywords: gtpase, polymer, filament, membrane, remodeling, fusion, mitochondria, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 34
• Total formula weight: 3934590.74

Authors

Du Pont, K.E.,Aydin, H. (deposition date: 2022-05-13, release date: 2023-08-30, Last modification date: 2023-09-13)

• Primary citation: von der Malsburg, A.,Sapp, G.M.,Zuccaro, K.E.,von Appen, A.,Moss 3rd, F.R.,Kalia, R.,Bennett, J.A.,Abriata, L.A.,Dal Peraro, M.,van der Laan, M.,Frost, A.,Aydin, H.; Structural mechanism of mitochondrial membrane remodelling by human OPA1.; Nature, 620:1101-1108, 2023; PubMed: 37612504; DOI: 10.1038/s41586-023-06441-6

Experimental method

ELECTRON MICROSCOPY (6.8 Å)