8SH3
| Pendrin in complex with iodide | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, IODIDE ION, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-13 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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8SHC
| Pendrin in complex with Niflumic acid | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-13 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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8SIE
| Pendrin in complex with bicarbonate | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, BICARBONATE ION, CHOLESTEROL, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-04-16 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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8KD5
| Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD3
| Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD4
| Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class1 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD6
| Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class3 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KC7
| Rpd3S histone deacetylase complex | Descriptor: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-06 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD2
| Rpd3S in complex with 187bp nucleosome | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD7
| Rpd3S in complex with nucleosome with H3K36MLA modification and 167bp DNA | Descriptor: | 167bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8UUK
| Pendrin in apo | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... | Authors: | Wang, L, Hoang, A, Zhou, M. | Deposit date: | 2023-11-01 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
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4E4Y
| The crystal structure of a short chain dehydrogenase family protein from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | GLYCEROL, SULFATE ION, Short chain dehydrogenase family protein | Authors: | Zhang, R, Zhou, M, Tan, K, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-13 | Release date: | 2012-03-28 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | The crystal structure of a short chain dehydrogenase family protein from Francisella tularensis subsp. tularensis SCHU S4 To be Published
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4EAE
| The crystal structure of a functionally unknown protein from Listeria monocytogenes EGD-e | Descriptor: | D-MALATE, Lmo1068 protein, SODIUM ION | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-22 | Release date: | 2012-04-04 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | The crystal structure of a functionally unknown protein from Listeria monocytogenes EGD-e To be Published
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6WF2
| Crystal structure of mouse SCD1 with a diiron center | Descriptor: | Acyl-CoA desaturase 1, FE (III) ION, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | Authors: | Shen, J, Zhou, M. | Deposit date: | 2020-04-03 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase. J.Mol.Biol., 432, 2020
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4E4R
| EutD phosphotransacetylase from Staphylococcus aureus | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Osipiuk, J, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-13 | Release date: | 2012-03-28 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | EutD phosphotransacetylase from Staphylococcus aureus. To be Published
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4FCA
| The crystal structure of a functionally unknown conserved protein from Bacillus anthracis str. Ames. | Descriptor: | Conserved domain protein, IMIDAZOLE, NICKEL (II) ION | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-24 | Release date: | 2012-06-06 | Method: | X-RAY DIFFRACTION (2.055 Å) | Cite: | The crystal structure of a functionally unknown conserved protein from Bacillus anthracis str. Ames. To be Published
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8DL7
| Cryo-EM structure of human ferroportin/slc40 bound to minihepcidin PR73 in nanodisc | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 11F9 heavy-chain, 11F9 light-chain, ... | Authors: | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | Deposit date: | 2022-07-07 | Release date: | 2022-12-07 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of ferroportin inhibition by minihepcidin PR73. Plos Biol., 21, 2023
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8DL8
| Cryo-EM structure of human ferroportin/slc40 bound to Co2+ in nanodisc | Descriptor: | 11F9 heavy-chain, 11F9 light-chain, COBALT (II) ION, ... | Authors: | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | Deposit date: | 2022-07-07 | Release date: | 2022-12-07 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of ferroportin inhibition by minihepcidin PR73. Plos Biol., 21, 2023
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8DL6
| Cryo-EM structure of human ferroportin/slc40 bound to Ca2+ in nanodisc | Descriptor: | 11F9 heavy-chain, 11F9 light-chain, CALCIUM ION, ... | Authors: | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | Deposit date: | 2022-07-07 | Release date: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism of Ca 2+ transport by ferroportin. Elife, 12, 2023
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6VP0
| Human Diacylglycerol Acyltransferase 1 in complex with oleoyl-CoA | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Diacylglycerol O-acyltransferase 1, Lauryl Maltose Neopentyl Glycol, ... | Authors: | Wang, L, Qian, H, Han, Y, Nian, Y, Ren, Z, Zhang, H, Hu, L, Prasad, B.V.V, Yan, N, Zhou, M. | Deposit date: | 2020-02-01 | Release date: | 2020-05-13 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature, 581, 2020
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8ERP
| Structure of Xenopus cholinephosphotransferase1 in complex with CDP-choline | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Cholinephosphotransferase 1, MAGNESIUM ION, ... | Authors: | Wang, L, Zhou, M. | Deposit date: | 2022-10-12 | Release date: | 2023-04-26 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of a eukaryotic cholinephosphotransferase-1 reveals mechanisms of substrate recognition and catalysis. Nat Commun, 14, 2023
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8ERO
| Structure of Xenopus cholinephosphotransferase1 in complex with CDP | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CYTIDINE-5'-DIPHOSPHATE, Cholinephosphotransferase 1, ... | Authors: | Wang, L, Zhou, M. | Deposit date: | 2022-10-12 | Release date: | 2023-04-26 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of a eukaryotic cholinephosphotransferase-1 reveals mechanisms of substrate recognition and catalysis. Nat Commun, 14, 2023
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4R9X
| Crystal Structure of Putative Copper Homeostasis Protein CutC from Bacillus anthracis | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Copper homeostasis protein CutC, ... | Authors: | Kim, Y, Zhou, M, Makowska-Grzyska, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-09-08 | Release date: | 2014-09-17 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.8515 Å) | Cite: | Crystal Structure of Putative Copper Homeostasis Protein CutC
from Bacillus anthracis To be Published, 2014
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4RWU
| J-domain of Sis1 protein, Hsp40 co-chaperone from Saccharomyces cerevisiae | Descriptor: | Protein SIS1 | Authors: | Osipiuk, J, Zhou, M, Gu, M, Sahi, C, Craig, E.A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-12-05 | Release date: | 2014-12-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Roles of intramolecular and intermolecular interactions in functional regulation of the Hsp70 J-protein co-chaperone Sis1. J.Mol.Biol., 427, 2015
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7TAI
| Structure of STEAP2 in complex with ligands | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wang, L, Chen, K.H, Zhou, M. | Deposit date: | 2021-12-20 | Release date: | 2023-01-25 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2. Elife, 12, 2023
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