1UZ8
 
 | | anti-Lewis X Fab fragment in complex with Lewis X | | Descriptor: | IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A, KAPPA) LIGHT CHAIN 291-2G3-A, ... | | Authors: | Van Roon, A.M.M, Pannu, N.S, De Vrind, J.P.M, Hokke, C.H, Deelder, A.M, Van Der marel, G.A, Van Boom, J.H, Abrahams, J.P. | | Deposit date: | 2004-03-05 | | Release date: | 2004-06-29 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen
Structure, 12, 2004
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1UZ6
 | | anti-Lewis X Fab fragment uncomplexed | | Descriptor: | IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A, KAPPA) LIGHT CHAIN 291-2G3-A, ... | | Authors: | Van Roon, A.M.M, Pannu, N.S, De Vrind, J.P.M, Hokke, C.H, Deelder, A.M, Van Der marel, G.A, Van Boom, J.H, Abrahams, J.P. | | Deposit date: | 2004-03-05 | | Release date: | 2004-06-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen
Structure, 12, 2004
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5LSL
 | | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | | Descriptor: | Cold sensitive U2 snRNA suppressor 1, Protein HSH49 | | Authors: | van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. | | Deposit date: | 2016-09-02 | | Release date: | 2017-04-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
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5LSB
 | | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | | Descriptor: | Cold sensitive U2 snRNA suppressor 1, Protein HSH49 | | Authors: | van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K. | | Deposit date: | 2016-08-24 | | Release date: | 2017-04-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
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2MY1
 | | Solution structure of Bud31p | | Descriptor: | Pre-mRNA-splicing factor BUD31, ZINC ION | | Authors: | van Roon, A.M, Yang, J, Mathieu, D, Bermel, W, Nagai, K, Neuhaus, D. | | Deposit date: | 2015-01-19 | | Release date: | 2015-03-11 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | (113) Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1W39
 | | Crystal structure of an artificial top component of turnip yellow mosaic virus | | Descriptor: | TURNIP YELLOW MOSAIC VIRUS EMPTY CAPSID | | Authors: | van Roon, A.M.M, Bink, H.H.J, Plaisier, J.R, Pleij, C.W.A, Abrahams, J.P, Pannu, N.S. | | Deposit date: | 2004-07-14 | | Release date: | 2004-08-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.75 Å) | | Cite: | Crystal Structure of an Empty Capsid of Turnip Yellow Mosaic Virus.
J.Mol.Biol., 341, 2004
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8OX0
 | | Structure of apo telomeric nucleosome | | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | | Deposit date: | 2023-04-28 | | Release date: | 2023-08-30 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
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8OX1
 | | Structure of TRF1core in complex with telomeric nucleosome | | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | | Deposit date: | 2023-04-28 | | Release date: | 2023-08-30 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
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8OUE
 | | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | | Deposit date: | 2023-04-22 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein.
Nat Commun, 15, 2024
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8OUF
 | | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | | Deposit date: | 2023-04-22 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein.
Nat Commun, 15, 2024
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7QXS
 | | Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) | | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | | Deposit date: | 2022-01-27 | | Release date: | 2022-03-02 | | Last modified: | 2022-03-23 | | Method: | ELECTRON MICROSCOPY (3.91 Å) | | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
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7BGB
 | | The H/ACA RNP lobe of human telomerase | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | | Deposit date: | 2021-01-06 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human telomerase holoenzyme with bound telomeric DNA.
Nature, 593, 2021
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7BG9
 | | The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate | | Descriptor: | DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... | | Authors: | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | | Deposit date: | 2021-01-06 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of human telomerase holoenzyme with bound telomeric DNA.
Nature, 593, 2021
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7QXA
 | | Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened) | | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | | Deposit date: | 2022-01-26 | | Release date: | 2022-03-02 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
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7QXB
 | | Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) | | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | | Deposit date: | 2022-01-26 | | Release date: | 2022-03-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
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2VQ1
 | | anti trimeric Lewis X Fab54-5C10-A | | Descriptor: | ANTI-HUMAN FC GAMMA RECEPTOR III 3G8 GAMMA HEAVY CHAIN VARIABLE REGION, AZIDE ION, GLYCEROL, ... | | Authors: | de Geus, D.C, van Roon, A.M.M, Thomassen, E.A.J, Hokke, C.H, Deelder, A.M, Abrahams, J.P. | | Deposit date: | 2008-03-10 | | Release date: | 2009-01-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Characterization of a Diagnostic Fab Fragment Binding Trimeric Lewis X.
Proteins, 76, 2009
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4PKD
 | | U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2 | | Descriptor: | IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ... | | Authors: | Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K. | | Deposit date: | 2014-05-14 | | Release date: | 2014-12-31 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
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4PJO
 | | Minimal U1 snRNP | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ETHANOL, ... | | Authors: | Kondo, Y, Oubridge, C, van Roon, A.M, Nagai, K. | | Deposit date: | 2014-05-12 | | Release date: | 2014-12-31 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
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2IWE
 | | Structure of a cavity mutant (H117G) of Pseudomonas aeruginosa azurin | | Descriptor: | 1,1'-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE), AZURIN, ZINC ION | | Authors: | De Jongh, T.E, Van Roon, A.M.M, Prudencio, M, Ubbink, M, Canters, G.W. | | Deposit date: | 2006-06-29 | | Release date: | 2007-06-12 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Click-Chemistry with an Active Site Variant of Azurin
Eur.J.Inorg.Chem., 2006, 2006
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2K0A
 | | 1H, 15N and 13C chemical shift assignments for Rds3 protein | | Descriptor: | Pre-mRNA-splicing factor RDS3, ZINC ION | | Authors: | Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D. | | Deposit date: | 2008-01-31 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5LEW
 | | DNA polymerase | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA polymerase III subunit alpha, SULFATE ION, ... | | Authors: | Banos-Mateos, S, Lang, U.F, Maslen, S.L, Skehel, J.M, Lamers, M.H. | | Deposit date: | 2016-06-30 | | Release date: | 2017-10-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center.
Nat Commun, 8, 2017
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4WZJ
 | | Spliceosomal U4 snRNP core domain | | Descriptor: | Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ... | | Authors: | Leung, A.K.W, Nagai, K, Li, J. | | Deposit date: | 2014-11-19 | | Release date: | 2015-01-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis.
Nature, 473, 2011
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2FZ2
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2FZ1
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