1RR2
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![BU of 1rr2 by Molmil](/molmil-images/mine/1rr2) | Propionibacterium shermanii transcarboxylase 5S subunit bound to 2-ketobutyric acid | Descriptor: | 2-KETOBUTYRIC ACID, COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2003-12-08 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1S3H
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![BU of 1s3h by Molmil](/molmil-images/mine/1s3h) | Propionibacterium shermanii transcarboxylase 5S subunit A59T | Descriptor: | COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2004-01-13 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1RQH
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![BU of 1rqh by Molmil](/molmil-images/mine/1rqh) | Propionibacterium shermanii transcarboxylase 5S subunit bound to pyruvic acid | Descriptor: | COBALT (II) ION, PYRUVIC ACID, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2003-12-05 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1RQB
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![BU of 1rqb by Molmil](/molmil-images/mine/1rqb) | Propionibacterium shermanii transcarboxylase 5S subunit | Descriptor: | COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2003-12-04 | Release date: | 2004-09-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1RQE
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![BU of 1rqe by Molmil](/molmil-images/mine/1rqe) | Propionibacterium shermanii transcarboxylase 5S subunit bound to oxaloacetate | Descriptor: | COBALT (II) ION, OXALOACETATE ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2003-12-05 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1U5J
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![BU of 1u5j by Molmil](/molmil-images/mine/1u5j) | Propionibacterium shermanii transcarboxylase 5S subunit, Met186Ile | Descriptor: | COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2004-07-27 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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1P9L
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![BU of 1p9l by Molmil](/molmil-images/mine/1p9l) | Structure of M. tuberculosis dihydrodipicolinate reductase in complex with NADH and 2,6 PDC | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRIDINE-2,6-DICARBOXYLIC ACID, TETRAETHYLENE GLYCOL, ... | Authors: | Cirilli, M, Zheng, R, Scapin, G, Blanchard, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-05-12 | Release date: | 2003-08-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity. Biochemistry, 42, 2003
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1ARZ
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![BU of 1arz by Molmil](/molmil-images/mine/1arz) | ESCHERICHIA COLI DIHYDRODIPICOLINATE REDUCTASE IN COMPLEX WITH NADH AND 2,6 PYRIDINE DICARBOXYLATE | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIHYDRODIPICOLINATE REDUCTASE, PHOSPHATE ION, ... | Authors: | Scapin, G, Reddy, S.G, Zheng, R, Blanchard, J.S. | Deposit date: | 1997-08-08 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Biochemistry, 36, 1997
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1BWZ
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![BU of 1bwz by Molmil](/molmil-images/mine/1bwz) | |
1C3V
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![BU of 1c3v by Molmil](/molmil-images/mine/1c3v) | DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC | Descriptor: | DIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | Authors: | Cirilli, M, Zheng, R, Scapin, G, Blanchard, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 1999-07-28 | Release date: | 2003-08-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | The three-dimensional structures of the Mycobacterium tuberculosis
dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes.
Structural and mutagenic analysis of relaxed nucleotide specificity Biochemistry, 42, 2003
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1WJF
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![BU of 1wjf by Molmil](/molmil-images/mine/1wjf) | SOLUTION STRUCTURE OF H12C MUTANT OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE COMPLEXED TO CADMIUM, NMR, 40 STRUCTURES | Descriptor: | CADMIUM ION, HIV-1 INTEGRASE | Authors: | Cai, M, Gronenborn, A.M, Clore, G.M. | Deposit date: | 1998-06-11 | Release date: | 1998-12-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium. Protein Sci., 7, 1998
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6LDZ
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![BU of 6ldz by Molmil](/molmil-images/mine/6ldz) | Crystal structure of Rv0222 from Mycobacterium tuberculosis | Descriptor: | Probable enoyl-CoA hydratase EchA1 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase) | Authors: | Li, J, Ran, Y.J, Wang, L, Wu, J.H, Ge, B.X, Rao, Z.H. | Deposit date: | 2019-11-23 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature, 577, 2020
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2EZX
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![BU of 2ezx by Molmil](/molmil-images/mine/2ezx) | |
2EZY
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![BU of 2ezy by Molmil](/molmil-images/mine/2ezy) | |
2EZZ
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![BU of 2ezz by Molmil](/molmil-images/mine/2ezz) | |
7SSB
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![BU of 7ssb by Molmil](/molmil-images/mine/7ssb) | Co-structure of PKG1 regulatory domain with compound 33 | Descriptor: | 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-nitrobenzoic acid, cGMP-dependent protein kinase 1 | Authors: | Fischmann, T.O. | Deposit date: | 2021-11-10 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1 alpha. J.Med.Chem., 65, 2022
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1QCK
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![BU of 1qck by Molmil](/molmil-images/mine/1qck) | |
1WJB
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![BU of 1wjb by Molmil](/molmil-images/mine/1wjb) | SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, 40 STRUCTURES | Descriptor: | HIV-1 INTEGRASE, ZINC ION | Authors: | Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
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1WJC
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![BU of 1wjc by Molmil](/molmil-images/mine/1wjc) | SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (E FORM), NMR, REGULARIZED MEAN STRUCTURE | Descriptor: | HIV-1 INTEGRASE, ZINC ION | Authors: | Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
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1WJE
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![BU of 1wje by Molmil](/molmil-images/mine/1wje) | SOLUTION STRUCTURE OF H12C MUTANT OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE COMPLEXED TO CADMIUM, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | CADMIUM ION, HIV-1 INTEGRASE | Authors: | Cai, M, Gronenborn, A.M, Clore, G.M. | Deposit date: | 1998-06-11 | Release date: | 1998-12-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium. Protein Sci., 7, 1998
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1WJA
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![BU of 1wja by Molmil](/molmil-images/mine/1wja) | SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, REGULARIZED MEAN STRUCTURE | Descriptor: | HIV-1 INTEGRASE, ZINC ION | Authors: | Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
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1WJD
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![BU of 1wjd by Molmil](/molmil-images/mine/1wjd) | SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (E FORM), NMR, 38 STRUCTURES | Descriptor: | HIV-1 INTEGRASE, ZINC ION | Authors: | Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
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4TN2
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![BU of 4tn2 by Molmil](/molmil-images/mine/4tn2) | NS5b in complex with lactam-thiophene carboxylic acids | Descriptor: | 3-[(2R)-2-cyclohexyl-5-oxopyrrolidin-1-yl]-5-phenylthiophene-2-carboxylic acid, Genome polyprotein | Authors: | Chopra, R. | Deposit date: | 2014-06-02 | Release date: | 2014-09-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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4TLR
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![BU of 4tlr by Molmil](/molmil-images/mine/4tlr) | NS5b in complex with lactam-thiophene carboxylic acids | Descriptor: | 3-{(2R,5R)-5-cyclohexyl-2-[(2R)-2-hydroxypropyl]-3-oxomorpholin-4-yl}-5-(3,3-dimethylbut-1-yn-1-yl)thiophene-2-carboxylic acid, 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, NS5b | Authors: | Chopra, R. | Deposit date: | 2014-05-30 | Release date: | 2014-12-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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1ZOS
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![BU of 1zos by Molmil](/molmil-images/mine/1zos) | Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA | Descriptor: | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase | Authors: | Shi, W, Singh, V, Zhen, R, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | Deposit date: | 2005-05-13 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Biochemistry, 45, 2006
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