Summary for 4TN2
| Descriptor | Genome polyprotein, 3-[(2R)-2-cyclohexyl-5-oxopyrrolidin-1-yl]-5-phenylthiophene-2-carboxylic acid (3 entities in total) |
|---|---|
| Functional Keywords | complex polymerase inhbitor, hydrolase |
| Biological source | Hepatitis B virus (isolate BK, HCV) |
| Total number of polymer chains | 1 |
| Total molecular weight | 64558.98 |
| Authors | Chopra, R. (deposition date: 2014-06-02, release date: 2014-09-17, Last modification date: 2017-11-22) |
| Primary citation | Barnes-Seeman, D.,Boiselle, C.,Capacci-Daniel, C.,Chopra, R.,Hoffmaster, K.,Jones, C.T.,Kato, M.,Lin, K.,Ma, S.,Pan, G.,Shu, L.,Wang, J.,Whiteman, L.,Xu, M.,Zheng, R.,Fu, J. Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorg.Med.Chem.Lett., 24:3979-3985, 2014 PubMed: 24986660 (PDB entries with the same primary citation) DOI: 10.1016/j.bmcl.2014.06.031  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
