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4V5N
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BU of 4v5n by Molmil
tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST)
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
3J7Z
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BU of 3j7z by Molmil
Structure of the E. coli 50S subunit with ErmCL nascent chain
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Arenz, S, Meydan, S, Starosta, A.L, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Wilson, D.N.
Deposit date:2014-08-27
Release date:2014-10-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation.
Mol.Cell, 56, 2014
4V5M
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BU of 4v5m by Molmil
tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
3DLL
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BU of 3dll by Molmil
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Descriptor: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P.
Deposit date:2008-06-27
Release date:2008-09-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
4Z3S
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BU of 4z3s by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 3'-deoxy-3'-{[(2E)-3-(4-{[(4Z)-6-O-(6-deoxy-3,4-di-O-methyl-alpha-D-mannopyranosyl)-5-O-methyl-alpha-D-threo-hex-4-enofuranosyl]oxy}phenyl)-2-methylprop-2-enoyl]amino}-N,N-dimethyladenosine, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-03-31
Release date:2015-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5DOX
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BU of 5dox by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-09-11
Release date:2015-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5DOY
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BU of 5doy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-09-11
Release date:2015-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
4V9B
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BU of 4v9b by Molmil
Crystal Structure of the 70S ribosome with tigecycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V9A
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BU of 4v9a by Molmil
Crystal Structure of the 70S ribosome with tetracycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2999 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
6ENJ
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BU of 6enj by Molmil
Polyproline-stalled ribosome in the presence of A+P site tRNA and elongation-factor P (EF-P)
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Huter, P, Wilson, D.N.
Deposit date:2017-10-05
Release date:2017-11-22
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
6ENU
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BU of 6enu by Molmil
Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P)
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Huter, P, Arenz, S, Wilson, D.N.
Deposit date:2017-10-06
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
6ENF
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BU of 6enf by Molmil
Cryo-EM structure of a polyproline-stalled ribosome in the absence of EF-P
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Huter, P, Arenz, S, Wilson, D.N.
Deposit date:2017-10-04
Release date:2017-11-22
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
5L3P
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BU of 5l3p by Molmil
Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Arenz, S, Wilson, D.N.
Deposit date:2016-05-24
Release date:2016-07-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.
Nucleic Acids Res., 44, 2016
2XL1
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BU of 2xl1 by Molmil
Structural basis of translational stalling by human cytomegalovirus (hCMV) and fungal arginine attenuator peptide (AAP)
Descriptor: ARGININE ATTENUATOR PEPTIDE
Authors:Meyer, N.H, Sattler, M.
Deposit date:2010-07-15
Release date:2010-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide.
Mol.Cell, 40, 2010

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