7ZQY
| Chaetomium thermophilum Rad50 Zn hook | Descriptor: | DH domain-containing protein, ZINC ION | Authors: | Lammens, K, Rotheneder, M, Stakyte, K. | Deposit date: | 2022-05-03 | Release date: | 2022-12-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
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7ZR1
| Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | Descriptor: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | Authors: | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | Deposit date: | 2022-05-03 | Release date: | 2023-01-11 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
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8BAH
| Human Mre11-Nbs1 complex | Descriptor: | Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin | Authors: | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | Deposit date: | 2022-10-11 | Release date: | 2023-01-11 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4.13 Å) | Cite: | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
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1FXR
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1A12
| REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN | Descriptor: | REGULATOR OF CHROMOSOME CONDENSATION 1 | Authors: | Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A. | Deposit date: | 1997-12-19 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller. Nature, 392, 1998
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1G94
| CRYSTAL STRUCTURE ANALYSIS OF THE TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS IN COMPLEX WITH A HEPTA-SACCHARIDE AND A TRIS MOLECULE | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Aghajari, N, Roth, M, Haser, R. | Deposit date: | 2000-11-22 | Release date: | 2001-12-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase. Biochemistry, 41, 2002
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1G9H
| TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA-AMYLASE, COMII (PSEUDO TRI-SACCHARIDE FROM BAYER) AND TRIS (2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, ... | Authors: | Aghajari, N, Roth, M, Haser, R. | Deposit date: | 2000-11-23 | Release date: | 2002-06-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic evidence of a transglycosylation reaction: ternary complexes of a
psychrophilic alpha-amylase. Biochemistry, 41, 2002
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3CAO
| OXIDISED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | Descriptor: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | Deposit date: | 1998-11-17 | Release date: | 2000-07-23 | Last modified: | 2018-04-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus. J.Mol.Biol., 290, 1999
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3CAR
| REDUCED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | Descriptor: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | Deposit date: | 1998-11-17 | Release date: | 2000-07-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus. J.Mol.Biol., 290, 1999
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2N3D
| Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR | Descriptor: | Bactofilin A | Authors: | Shi, C, Fricke, P, Lin, L, Chevelkov, V, Wegstroth, M, Giller, K, Becker, S, Thanbichler, M, Lange, A. | Deposit date: | 2015-05-29 | Release date: | 2015-12-16 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR. Sci Adv, 1, 2015
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2AEV
| MJ0158, NaBH4-reduced form | Descriptor: | Hypothetical protein MJ0158, SULFATE ION | Authors: | Kaiser, J.T, Gromadski, K, Rother, M, Engelhardt, H, Rodnina, M.V, Wahl, M.C. | Deposit date: | 2005-07-24 | Release date: | 2005-10-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional investigation of a putative archaeal selenocysteine synthase Biochemistry, 44, 2005
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2AEU
| MJ0158, apo form | Descriptor: | Hypothetical protein MJ0158, SULFATE ION | Authors: | Kaiser, J.T, Gromadski, K, Rother, M, Engelhardt, H, Rodnina, M.V, Wahl, M.C. | Deposit date: | 2005-07-24 | Release date: | 2005-10-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional investigation of a putative archaeal selenocysteine synthase Biochemistry, 44, 2005
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7NI4
| Human ATM kinase domain with bound M4076 inhibitor | Descriptor: | 8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoranyl-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-imidazo[4,5-c]quinolin-2-one, Serine-protein kinase ATM, ZINC ION | Authors: | Stakyte, K, Rotheneder, M. | Deposit date: | 2021-02-11 | Release date: | 2021-09-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis of human ATM kinase inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7NI5
| Human ATM kinase with bound inhibitor KU-55933 | Descriptor: | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one, Serine-protein kinase ATM, ZINC ION | Authors: | Bartho, J.D, Stakyte, K, Rotheneder, M, Lammens, K, Hopfner, K.P. | Deposit date: | 2021-02-11 | Release date: | 2021-09-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Molecular basis of human ATM kinase inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7NI6
| Human ATM kinase with bound ATPyS | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM, ... | Authors: | Stakyte, K, Rotheneder, M, Lammens, K, Bartho, J.D. | Deposit date: | 2021-02-11 | Release date: | 2021-09-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular basis of human ATM kinase inhibition. Nat.Struct.Mol.Biol., 28, 2021
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4C4Y
| Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A4 | Descriptor: | 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | Deposit date: | 2013-09-09 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4X
| Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9 | Descriptor: | 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | Deposit date: | 2013-09-09 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4Z
| Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 | Descriptor: | 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | Deposit date: | 2013-09-09 | Release date: | 2014-10-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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7TGP
| E176T/Y188G variant of the internal UBA Domain of HHR23A | Descriptor: | UV excision repair protein RAD23 homolog A | Authors: | Rothfuss, M, Bowler, B.E, McClelland, L.J, Sprang, S.R. | Deposit date: | 2022-01-08 | Release date: | 2023-04-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST. J.Am.Chem.Soc., 145, 2023
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4NZG
| Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Integrase p46, ... | Authors: | Guan, R, Jiang, M, Janjua, H, Maglaqui, M, Zhao, L, Xiao, R, Acton, T.B, Everett, J.K, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-12-12 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
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3NNQ
| Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | Descriptor: | ACETATE ION, N-terminal domain of Moloney murine leukemia virus integrase, ZINC ION | Authors: | Guan, R, Xiao, R, Acton, T, Jiang, M, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-24 | Release date: | 2010-07-14 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
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2ACK
| ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA | Descriptor: | ACETYLCHOLINESTERASE, EDROPHONIUM ION | Authors: | Raves, M.L, Sussman, J.L, Harel, M, Silman, I. | Deposit date: | 1997-10-29 | Release date: | 1998-02-11 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Static Laue diffraction studies on acetylcholinesterase. Acta Crystallogr.,Sect.D, 54, 1998
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6T9E
| Crystal structure of a bispecific DutaFab in complex with human PDGF | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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1AX9
| ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, LAUE DATA | Descriptor: | ACETYLCHOLINESTERASE, EDROPHONIUM ION | Authors: | Raves, M.L, Ravelli, R.B.G, Sussman, J.L, Harel, M, Silman, I. | Deposit date: | 1997-11-03 | Release date: | 1998-02-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Static Laue diffraction studies on acetylcholinesterase. Acta Crystallogr.,Sect.D, 54, 1998
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1A2E
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