1A2E
CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA DECAMER CONTAINING A CISPLATIN INTERSTRAND CROSS-LINK ADDUCT
Summary for 1A2E
Entry DOI | 10.2210/pdb1a2e/pdb |
Descriptor | DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3'), Cisplatin, ... (4 entities in total) |
Functional Keywords | antitumor drug, cis-ddp, interstrand cross-link, dna |
Total number of polymer chains | 2 |
Total formula weight | 6391.04 |
Authors | Coste, F.,Zelwer, C. (deposition date: 1998-01-05, release date: 1999-04-12, Last modification date: 2024-02-07) |
Primary citation | Coste, F.,Malinge, J.M.,Serre, L.,Shepard, W.,Roth, M.,Leng, M.,Zelwer, C. Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site. Nucleic Acids Res., 27:1837-1846, 1999 Cited by PubMed: 10101191DOI: 10.1093/nar/27.8.1837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
Download full validation report