8VY3
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![BU of 8vy3 by Molmil](/molmil-images/mine/8vy3) | Human DNA polymerase alpha/primase - AavLEA1 (1:40 molar ratio) | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | Authors: | Abe, K.M, Li, G, Grant, T, Lim, C.J. | Deposit date: | 2024-02-06 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Human PRC2 - AavLEA1 (1:40 molar ratio) To Be Published
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6W6W
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![BU of 6w6w by Molmil](/molmil-images/mine/6w6w) | Cryo-EM structure of CST bound to telomeric single-stranded DNA | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | Lim, C, Barbour, A.T, Zaug, A.J, Goodrich, K.J, McKay, A.E, Wuttke, D.S, Cech, T.R. | Deposit date: | 2020-03-17 | Release date: | 2020-06-03 | Last modified: | 2020-06-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science, 368, 2020
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8D0K
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![BU of 8d0k by Molmil](/molmil-images/mine/8d0k) | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | Deposit date: | 2022-05-26 | Release date: | 2022-06-22 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
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8D0B
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![BU of 8d0b by Molmil](/molmil-images/mine/8d0b) | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | Deposit date: | 2022-05-26 | Release date: | 2022-06-22 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
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8D9D
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![BU of 8d9d by Molmil](/molmil-images/mine/8d9d) | Human DNA polymerase-alpha/primase elongation complex II bound to primer/template | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | Authors: | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | Deposit date: | 2022-06-09 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
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8D96
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![BU of 8d96 by Molmil](/molmil-images/mine/8d96) | Human DNA polymerase alpha/primase elongation complex I bound to primer/template | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | Authors: | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | Deposit date: | 2022-06-09 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
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4ZRI
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![BU of 4zri by Molmil](/molmil-images/mine/4zri) | Crystal structure of Merlin-FERM and Lats2 | Descriptor: | Merlin, Serine/threonine-protein kinase LATS2 | Authors: | Li, F, Zhou, H, Long, J, Shen, Y. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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4ZRJ
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![BU of 4zrj by Molmil](/molmil-images/mine/4zrj) | Structure of Merlin-FERM and CTD | Descriptor: | GLYCEROL, Merlin | Authors: | Lin, Z, Li, F, Long, J, Shen, Y. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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3JUA
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![BU of 3jua by Molmil](/molmil-images/mine/3jua) | |
5GN0
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![BU of 5gn0 by Molmil](/molmil-images/mine/5gn0) | Structure of TAZ-TEAD complex | Descriptor: | CITRIC ACID, PALMITIC ACID, Transcriptional enhancer factor TEF-3, ... | Authors: | Kaan, H.Y.K, Song, H. | Deposit date: | 2016-07-18 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex Sci Rep, 7, 2017
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5XJD
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![BU of 5xjd by Molmil](/molmil-images/mine/5xjd) | TEAD in complex with fragment | Descriptor: | (2S)-2-phenyl-2-pyrrol-1-yl-ethanoic acid, Transcriptional enhancer factor TEF-3 | Authors: | Kaan, H.Y.K, Sim, A.Y.L, Tan, S.K.J, Verma, C, Song, H. | Deposit date: | 2017-05-01 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches. PLoS ONE, 12, 2017
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4ZRK
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![BU of 4zrk by Molmil](/molmil-images/mine/4zrk) | Merlin-FERM and Lats1 complex | Descriptor: | Merlin, Serine/threonine-protein kinase LATS1 | Authors: | Lin, Z, Li, Y, Wei, Z, Zhang, M. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.316 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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3L15
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![BU of 3l15 by Molmil](/molmil-images/mine/3l15) | Human Tead2 transcriptional factor | Descriptor: | GLYCEROL, Transcriptional enhancer factor TEF-4 | Authors: | Tomchick, D.R, Luo, X, Tian, W. | Deposit date: | 2009-12-10 | Release date: | 2010-04-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc.Natl.Acad.Sci.USA, 107, 2010
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