4X57
 
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8FZT
 | | SpCas9 with dual-guide RNA and target DNA | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, CrE2, E2-NTS, ... | | Authors: | Korolev, S, Gagnon, K. | | Deposit date: | 2023-01-30 | | Release date: | 2023-05-31 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | SpCas9 with dual-guide RNA and target DNA
To Be Published
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8G1I
 | | SpCas9 with sgRNA and target DNA | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA E2_NTS, DNA E2_TS, ... | | Authors: | Korolev, S, Gagnon, K. | | Deposit date: | 2023-02-02 | | Release date: | 2023-05-17 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | SpCas9 with sgRNA and target DNA
To Be Published
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1UAA
 | | E. COLI REP HELICASE/DNA COMPLEX | | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), PROTEIN (ATP-DEPENDENT DNA HELICASE REP.) | | Authors: | Korolev, S, Waksman, G. | | Deposit date: | 1997-06-30 | | Release date: | 1998-07-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP.
Cell(Cambridge,Mass.), 90, 1997
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1K6D
 | | CRYSTAL STRUCTURE OF ACETATE COA-TRANSFERASE ALPHA SUBUNIT | | Descriptor: | ACETATE COA-TRANSFERASE ALPHA SUBUNIT, MAGNESIUM ION | | Authors: | Korolev, S, Koroleva, O, Petterson, K, Collart, F, Dementieva, I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-10-15 | | Release date: | 2002-06-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data.
Acta Crystallogr.,Sect.D, 58, 2002
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1INL
 | | Crystal Structure of Spermidine Synthase from Thermotoga Maritima | | Descriptor: | Spermidine synthase | | Authors: | Korolev, S, Skarina, T, Ikeguchi, Y, Pegg, A.E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-05-14 | | Release date: | 2001-11-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Nat.Struct.Biol., 9, 2002
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1JQ3
 | | Crystal Structure of Spermidine Synthase in Complex with Transition State Analogue AdoDATO | | Descriptor: | S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, Spermidine synthase | | Authors: | Korolev, S, Ikeguchi, Y, Skarina, T, Beasley, S, Edwards, A, Joachimiak, A, Pegg, A.E, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-08-03 | | Release date: | 2001-11-21 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Nat.Struct.Biol., 9, 2002
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1KXJ
 | | The Crystal Structure of Glutamine Amidotransferase from Thermotoga maritima | | Descriptor: | Amidotransferase hisH, PHOSPHATE ION | | Authors: | Korolev, S, Skarina, T, Evdokimova, E, Beasley, S, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2002-01-31 | | Release date: | 2002-03-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of glutamine amidotransferase from Thermotoga maritima
Proteins, 49, 2002
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1ML8
 | | structural genomics | | Descriptor: | hypothetical protein (crp region) | | Authors: | Korolev, S, Skarina, T, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2002-08-30 | | Release date: | 2003-04-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural genomics
To be Published
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1KTQ
 | | DNA POLYMERASE | | Descriptor: | DNA POLYMERASE I | | Authors: | Korolev, S, Waksman, G. | | Deposit date: | 1995-08-16 | | Release date: | 1996-11-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
Proc.Natl.Acad.Sci.USA, 92, 1995
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7S4A
 | | MRG15 complex with PALB2 peptide | | Descriptor: | Mortality factor 4-like protein 1, Partner and localizer of BRCA2 | | Authors: | Korolev, S, Deveryshetty, J. | | Deposit date: | 2021-09-08 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.693 Å) | | Cite: | Structural Insight into the Mechanism of PALB2 Interaction with MRG15.
Genes (Basel), 12, 2021
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2O5V
 | | Recombination mediator RecF | | Descriptor: | DNA replication and repair protein recF, SULFATE ION | | Authors: | Korolev, S, Koroleva, O. | | Deposit date: | 2006-12-06 | | Release date: | 2007-02-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structural conservation of RecF and Rad50: implications for DNA recognition and RecF function.
Embo J., 26, 2007
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3LFU
 | | Crystal Structure of E. coli UvrD | | Descriptor: | DNA helicase II, SULFATE ION | | Authors: | Korolev, S, Waksman, G, Lohman, T.M. | | Deposit date: | 2010-01-18 | | Release date: | 2011-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding.
J.Mol.Biol., 411, 2011
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1NPY
 | | Structure of shikimate 5-dehydrogenase-like protein HI0607 | | Descriptor: | ACETYL GROUP, Hypothetical shikimate 5-dehydrogenase-like protein HI0607 | | Authors: | Korolev, S, Koroleva, O, Zarembinski, T, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2003-01-20 | | Release date: | 2003-07-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structure of a Novel Shikimate Dehydrogenase from Haemophilus influenzae.
J.Biol.Chem., 280, 2005
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7N8K
 | | LINE-1 endonuclease domain complex with Mg | | Descriptor: | ACETATE ION, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | Authors: | Korolev, S, Miller, I. | | Deposit date: | 2021-06-15 | | Release date: | 2021-10-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Nucleic Acids Res., 49, 2021
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7N8S
 | | LINE-1 endonuclease domain complex with DNA | | Descriptor: | DNA (5'-D(*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*A)-3'), LINE-1 retrotransposable element ORF2 protein | | Authors: | Korolev, S, Miller, I. | | Deposit date: | 2021-06-15 | | Release date: | 2021-10-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Nucleic Acids Res., 49, 2021
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7N94
 | | LINE-1 endonuclease domain complex with DNA | | Descriptor: | DNA (5'-D(*AP*GP*CP*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*GP*CP*TP*A)-3'), LINE-1 retrotransposable element ORF2 protein | | Authors: | Korolev, S, Miller, I. | | Deposit date: | 2021-06-16 | | Release date: | 2021-10-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Nucleic Acids Res., 49, 2021
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6AUN
 | | calcium-independent phospholipase A2 beta | | Descriptor: | PLA2G6, iPLA2beta | | Authors: | Malley, K, Koroleva, O, Miller, I, Sanishvili, R, Jenkins, C.M, Gross, R.W, Korolev, S. | | Deposit date: | 2017-09-01 | | Release date: | 2018-03-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.951 Å) | | Cite: | The structure of iPLA2beta reveals dimeric active sites and suggests mechanisms of regulation and localization.
Nat Commun, 9, 2018
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1U5K
 | | Recombinational repair protein RecO | | Descriptor: | ZINC ION, hypothetical protein | | Authors: | Makharashvili, N, Koroleva, O, Bera, S, Grandgenett, D.P, Korolev, S. | | Deposit date: | 2004-07-27 | | Release date: | 2004-10-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Novel Structure of DNA Repair Protein RecO from Deinococcus radiodurans
STRUCTURE, 12, 2004
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3Q8D
 | | E. coli RecO complex with SSB C-terminus | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, D-MALATE, DNA repair protein recO, ... | | Authors: | Koroleva, O, Ryzhikov, M, Korolev, S. | | Deposit date: | 2011-01-06 | | Release date: | 2011-05-04 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanism of RecO recruitment to DNA by single-stranded DNA binding protein.
Nucleic Acids Res., 39, 2011
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5KTQ
 | | LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, PROTEIN (DNA POLYMERASE I) | | Authors: | Li, Y, Kong, Y, Korolev, S, Waksman, G. | | Deposit date: | 1998-09-22 | | Release date: | 1998-09-30 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates.
Protein Sci., 7, 1998
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1YMP
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3ULP
 | | Plasmodium falciparum SSB complex with ssDNA | | Descriptor: | DNA (35-MER), Single-strand binding protein | | Authors: | Antony, E, Lohman, T.M, Korolev, S. | | Deposit date: | 2011-11-11 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Plasmodium falciparum SSB Tetramer Wraps Single-Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB.
J.Mol.Biol., 420, 2012
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1FGU
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1L1O
 | | Structure of the human Replication Protein A (RPA) trimerization core | | Descriptor: | Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ... | | Authors: | Bochkareva, E.V, Korolev, S, Lees-Miller, S.P, Bochkarev, A. | | Deposit date: | 2002-02-19 | | Release date: | 2002-06-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.
EMBO J., 21, 2002
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