8RH7
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![BU of 8rh7 by Molmil](/molmil-images/mine/8rh7) | CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in primed state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ESTRADIOL, ... | Authors: | Chen, F, John, C, Rebecca, J.H, Erik, L. | Deposit date: | 2023-12-15 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor Nat Commun, 2024
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8RHG
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![BU of 8rhg by Molmil](/molmil-images/mine/8rhg) | CryoEM structure of human rho1 GABAA receptor in complex with GABA and pregnenolone sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Chen, F, John, C, Rebecca, J.H, Erik, L. | Deposit date: | 2023-12-15 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor Nat Commun, 2024
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8RH9
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![BU of 8rh9 by Molmil](/molmil-images/mine/8rh9) | CryoEM structure of human rho1 GABAA receptor in complex with pregnenolone sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Chen, F, John, C, Rebecca, J.H, Erik, L. | Deposit date: | 2023-12-15 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor Nat Commun, 2024
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8RH4
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![BU of 8rh4 by Molmil](/molmil-images/mine/8rh4) | CryoEM structure of human rho1 GABAA receptor in complex with estradiol | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Chen, F, John, C, Rebecca, J.H, Erik, L. | Deposit date: | 2023-12-14 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor Nat Commun, 2024
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8RH8
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![BU of 8rh8 by Molmil](/molmil-images/mine/8rh8) | CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in desensitized state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Chen, F, John, C, Rebecca, J.H, Erik, L. | Deposit date: | 2023-12-15 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor Nat Commun, 2024
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4S1Z
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![BU of 4s1z by Molmil](/molmil-images/mine/4s1z) | Crystal structure of TRABID NZF1 in complex with K29 linked di-Ubiquitin | Descriptor: | Ubiquitin, Ubiquitin thioesterase ZRANB1, ZINC ION | Authors: | Kristariyanto, Y.A, Abdul Rehman, S.A, Campbell, D.G, Morrice, N.A, Johnson, C, Toth, R, Kulathu, Y. | Deposit date: | 2015-01-16 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin. Mol.Cell, 58, 2015
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4S22
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![BU of 4s22 by Molmil](/molmil-images/mine/4s22) | Crystal structure of K29 linked di-Ubiquitin | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ... | Authors: | Kristariyanto, Y.A, Abdul Rehman, S.A, Campbell, D.G, Morrice, N.A, Johnson, C, Toth, R, Kulathu, Y. | Deposit date: | 2015-01-17 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin. Mol.Cell, 58, 2015
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5N2W
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![BU of 5n2w by Molmil](/molmil-images/mine/5n2w) | WT-Parkin and pUB complex | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ... | Authors: | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | Deposit date: | 2017-02-08 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
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5N38
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![BU of 5n38 by Molmil](/molmil-images/mine/5n38) | S65DParkin and pUB complex | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ... | Authors: | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | Deposit date: | 2017-02-08 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24, 2017
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1XGK
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![BU of 1xgk by Molmil](/molmil-images/mine/1xgk) | CRYSTAL STRUCTURE OF N12G AND A18G MUTANT NMRA | Descriptor: | CHLORIDE ION, GLYCEROL, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, ... | Authors: | Lamb, H.K, Ren, J, Park, A, Johnson, C, Leslie, K, Cocklin, S, Thompson, P, Mee, C, Cooper, A, Stammers, D.K, Hawkins, A.R. | Deposit date: | 2004-09-17 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis Protein Sci., 13, 2004
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2VUS
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![BU of 2vus by Molmil](/molmil-images/mine/2vus) | Crystal structure of unliganded NmrA-AreA zinc finger complex | Descriptor: | CHLORIDE ION, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... | Authors: | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | Deposit date: | 2008-05-30 | Release date: | 2008-07-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
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2VUT
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![BU of 2vut by Molmil](/molmil-images/mine/2vut) | Crystal structure of NAD-bound NmrA-AreA zinc finger complex | Descriptor: | CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | Deposit date: | 2008-05-30 | Release date: | 2008-07-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
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2VUU
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![BU of 2vuu by Molmil](/molmil-images/mine/2vuu) | Crystal structure of NADP-bound NmrA-AreA zinc finger complex | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... | Authors: | Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. | Deposit date: | 2008-05-30 | Release date: | 2008-07-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
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1TI7
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![BU of 1ti7 by Molmil](/molmil-images/mine/1ti7) | CRYSTAL STRUCTURE OF NMRA, A NEGATIVE TRANSCRIPTIONAL REGULATOR, IN COMPLEX WITH NADP AT 1.7A RESOLUTION | Descriptor: | CHLORIDE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lamb, H.K, Leslie, K, Dodds, A.L, Nutley, M, Cooper, A, Johnson, C, Thompson, P, Stammers, D.K, Hawkins, A.R. | Deposit date: | 2004-06-02 | Release date: | 2004-06-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides. J.Biol.Chem., 278, 2003
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8OQ7
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![BU of 8oq7 by Molmil](/molmil-images/mine/8oq7) | CryoEM structure of human rho1 GABAA receptor in complex with inhibitor TPMPA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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8OQ8
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![BU of 8oq8 by Molmil](/molmil-images/mine/8oq8) | CryoEM structure of human rho1 GABAA receptor in complex with pore blocker picrotoxin | Descriptor: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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8OQA
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![BU of 8oqa by Molmil](/molmil-images/mine/8oqa) | CryoEM structure of human rho1 GABAA receptor in complex with GABA and picrotoxin | Descriptor: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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8OP9
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![BU of 8op9 by Molmil](/molmil-images/mine/8op9) | CryoEM structure of human rho1 GABAA receptor in complex with GABA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-06 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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8OQ6
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![BU of 8oq6 by Molmil](/molmil-images/mine/8oq6) | CryoEM structure of human rho1 GABAA receptor apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | Authors: | Chen, F, Victor, T, John, C, Rebecca, J.H, Lindahl, E. | Deposit date: | 2023-04-11 | Release date: | 2023-08-30 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structure and dynamics of differential ligand binding in the human rho-type GABA A receptor. Neuron, 111, 2023
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6MDU
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![BU of 6mdu by Molmil](/molmil-images/mine/6mdu) | Crystal structure of NDM-1 with compound 7 | Descriptor: | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide, GLYCEROL, Metallo-beta-lactamase type 2, ... | Authors: | Akhtar, A, Chen, Y. | Deposit date: | 2018-09-05 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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8A67
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![BU of 8a67 by Molmil](/molmil-images/mine/8a67) | |
5UHV
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![BU of 5uhv by Molmil](/molmil-images/mine/5uhv) | wild-type NRas bound to GppNHp | Descriptor: | GLYCEROL, GTPase NRas, MAGNESIUM ION, ... | Authors: | Reid, D, Johnson, C, Salter, S, Mattos, C. | Deposit date: | 2017-01-12 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.672 Å) | Cite: | The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects. J. Biol. Chem., 292, 2017
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7KDT
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![BU of 7kdt by Molmil](/molmil-images/mine/7kdt) | |
8DTX
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![BU of 8dtx by Molmil](/molmil-images/mine/8dtx) | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV89-22 | Descriptor: | COV89-22 heavy chain, COV89-22 light chain, Spike protein S2' stem helix peptide | Authors: | Lin, T.H, Lee, C.C.D, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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8DTR
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![BU of 8dtr by Molmil](/molmil-images/mine/8dtr) | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV30-14 | Descriptor: | COV30-14 heavy chain, COV30-14 light chain, Spike protein S2' stem helix peptide | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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