8RH8

CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in desensitized state

Summary for 8RH8

• Entry DOI: 10.2210/pdb8rh8/pdb
• EMDB information: 19172
• Descriptor: Gamma-aminobutyric acid receptor subunit rho-1, GAMMA-AMINO-BUTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: complex, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 284984.65

Authors

Chen, F.,John, C.,Rebecca, J.H.,Erik, L. (deposition date: 2023-12-15, release date: 2024-08-28, Last modification date: 2025-07-02)

• Primary citation: Chen, F.,John, C.,Rebecca, J.H.,Erik, L.; Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor; Nat Commun, 2024

Experimental method

ELECTRON MICROSCOPY (2.66 Å)