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1GAX
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BU of 1gax by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
Descriptor: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, TRNA(VAL), VALYL-TRNA SYNTHETASE, ...
Authors:Fukai, S, Nureki, O, Sekine, S, Shimada, A, Tao, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2000-06-23
Release date:2000-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase.
Cell(Cambridge,Mass.), 103, 2000
1IVS
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BU of 1ivs by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
Descriptor: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, Valyl-tRNA synthetase, tRNA (Val)
Authors:Fukai, S, Nureki, O, Sekine, S.-I, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-03-29
Release date:2003-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
1IYW
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BU of 1iyw by Molmil
Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase
Descriptor: Valyl-tRNA Synthetase
Authors:Fukai, S, Nureki, O, Sekine, S, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-09-10
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (4 Å)
Cite:Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
1UAD
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BU of 1uad by Molmil
Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex
Descriptor: Exocyst complex component Sec5, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fukai, S, Matern, H.T, Scheller, R.H, Brunger, A.T.
Deposit date:2003-03-09
Release date:2003-07-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the interaction between RalA and Sec5, a subunit of the Sec6/8 complex
EMBO J., 22, 2003
2E7S
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BU of 2e7s by Molmil
Crystal structure of the yeast Sec2p GEF domain
Descriptor: Rab guanine nucleotide exchange factor SEC2
Authors:Fukai, S, Sato, Y, Nureki, O.
Deposit date:2007-01-12
Release date:2007-02-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity
Structure, 15, 2007
4UBQ
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BU of 4ubq by Molmil
Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp.
Descriptor: ACETATE ION, Beta-lactamase, ZINC ION
Authors:Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H.
Deposit date:2014-08-13
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2.
Biol.Pharm.Bull., 38, 2015
8J6N
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BU of 8j6n by Molmil
Crystal structure of Cystathionine gamma-lyase in complex with compound 1
Descriptor: 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ...
Authors:Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K.
Deposit date:2023-04-26
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.
Sci Rep, 13, 2023
5DST
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BU of 5dst by Molmil
Crystal structure of human PRMT8 in complex with SAH
Descriptor: Protein arginine N-methyltransferase 8, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Toma-Fukai, S, Shimizu, T.
Deposit date:2015-09-17
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.963 Å)
Cite:Novel helical assembly in arginine methyltransferase 8
J.Mol.Biol., 428, 2016
1HLV
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BU of 1hlv by Molmil
CRYSTAL STRUCTURE OF CENP-B(1-129) COMPLEXED WITH THE CENP-B BOX DNA
Descriptor: CENP-B BOX DNA, MAJOR CENTROMERE AUTOANTIGEN B
Authors:Tanaka, Y, Nureki, O, Kurumizaka, H, Fukai, S, Kawaguchi, S, Ikuta, M, Iwahara, J, Okazaki, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2000-12-04
Release date:2002-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.
EMBO J., 20, 2001
3VON
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BU of 3von by Molmil
Crystalstructure of the ubiquitin protease
Descriptor: Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Sato, Y, Fukai, S.
Deposit date:2012-01-30
Release date:2012-05-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13.
J.Biol.Chem., 287, 2012
3VLC
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BU of 3vlc by Molmil
Crystal structure of S. cerevisiae Get3 in the semi open conformation in complex with Get1 cytosolic domain at 4.5 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 1
Authors:Kubota, K, Yamagata, A, Fukai, S.
Deposit date:2011-11-30
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces
J.Mol.Biol., 422, 2012
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
Descriptor: NF-kappa-B essential modulator, Ubiquitin
Authors:Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
Deposit date:2009-09-11
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
1WY5
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BU of 1wy5 by Molmil
Crystal structure of isoluecyl-tRNA lysidine synthetase
Descriptor: Hypothetical UPF0072 protein AQ_1887
Authors:Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-06
Release date:2005-05-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
7BY1
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BU of 7by1 by Molmil
Crystal structure of GCN5 PCAF N-terminal domain
Descriptor: Histone acetyltransferase KAT2A, ZINC ION
Authors:Hibi, R, Toma-Fukai, S, Shimizu, T.
Deposit date:2020-04-21
Release date:2020-08-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
J.Biol.Chem., 295, 2020
5B86
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BU of 5b86 by Molmil
Crystal structure of M-Sec
Descriptor: Tumor necrosis factor alpha-induced protein 2
Authors:Yamashita, M, Sato, Y, Yamagata, A, Fukai, S.
Deposit date:2016-06-12
Release date:2016-10-12
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (3.017 Å)
Cite:Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.
Sci Rep, 6, 2016
3W0W
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BU of 3w0w by Molmil
The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide in space group P212121
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-11-05
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
3VXS
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BU of 3vxs by Molmil
The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(6L) peptide
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, H27-14 TCR alpha chain, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
3VXP
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BU of 3vxp by Molmil
HLA-A24 in complex with HIV-1 Nef134-10(6L)
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
3VXT
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BU of 3vxt by Molmil
T36-5 TCR specific for HLA-A24-Nef134-10
Descriptor: T36-5 TCR alpha chain, T36-5 TCR beta chain
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
3VXR
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BU of 3vxr by Molmil
The complex between H27-14 TCR and HLA-A24 bound to HIV-1 Nef134-10(wt) peptide
Descriptor: 10-mer peptide from Protein Nef, Beta-2-microglobulin, H27-14 TCR alpha chain, ...
Authors:Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A.
Deposit date:2012-09-20
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
SCI REP, 3, 2013
7CEE
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BU of 7cee by Molmil
Crystal structure of mouse neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.763 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7CEG
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BU of 7ceg by Molmil
Crystal structure of the complex between mouse PTP delta and neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7E62
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BU of 7e62 by Molmil
Mouse TAB2 NZF in complex with Lys6-linked diubiquitin
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ...
Authors:Sato, Y, Li, Y, Okatsu, K, Fukai, S.
Deposit date:2021-02-21
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for specific recognition of K6-linked polyubiquitin chains by the TAB2 NZF domain.
Biophys.J., 120, 2021
7EXE
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BU of 7exe by Molmil
Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide
Descriptor: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22
Authors:Yan, L, Okatsu, K, Fukai, S.
Deposit date:2021-05-27
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice
Cell Rep, 2021
7CQF
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BU of 7cqf by Molmil
Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2020-08-10
Release date:2021-01-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.
Proc.Natl.Acad.Sci.USA, 118, 2021

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