3GE3
| Crystal Structure of the reduced Toluene 4-Monooxygenase HD T201A mutant complex | Descriptor: | ACETATE ION, CHLORIDE ION, FE (III) ION, ... | Authors: | Elsen, N.L, Bailey, L.J, Fox, B.G. | Deposit date: | 2009-02-24 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase. Biochemistry, 48, 2009
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3GE8
| Toluene 4-monooxygenase HD T201A diferric, resting state complex | Descriptor: | ACETATE ION, FE (III) ION, Toluene-4-monooxygenase system protein A, ... | Authors: | Elsen, N.L, Bailey, L.J, Hauser, A.D, Fox, B.G. | Deposit date: | 2009-02-25 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase. Biochemistry, 48, 2009
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5UHL
| Crystal structure of the core catalytic domain of human O-GlcNAcase complexed with Thiamet G | Descriptor: | (2Z,3aR,5R,6S,7R,7aR)-2-(ethylimino)-5-(hydroxymethyl)hexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain | Authors: | Klein, D.J, Elsen, N.L. | Deposit date: | 2017-01-11 | Release date: | 2017-03-29 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Crystal structure of the core catalytic domain of human O-GlcNAcase and molecular basis of activity and inhibition To Be Published
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5UHO
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5UHK
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5UHP
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3D89
| Crystal Structure of a Soluble Rieske Ferredoxin from Mus musculus | Descriptor: | 1,2-ETHANEDIOL, FE2/S2 (INORGANIC) CLUSTER, Rieske domain-containing protein | Authors: | Levin, E.J, McCoy, J.G, Elsen, N.L, Seder, K.D, Bingman, C.A, Wesenberg, G.E, Fox, B.G, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2008-05-22 | Release date: | 2008-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.071 Å) | Cite: | X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus. Acta Crystallogr.,Sect.D, 64, 2008
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5HD7
| Dissecting Therapeutic Resistance to ERK Inhibition Rat Mutant SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | Descriptor: | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | Jha, S, Morris, E.J, Hruza, A, Mansueto, M.S, Schroeder, G, Arbanas, J, McMasters, D, Restaino, C.R, Dayananth, R, Black, S, Elsen, N.L, Mannarino, A, Cooper, A, Fawell, S, Zawel, L, Jayaraman, L, Samatar, A.A. | Deposit date: | 2016-01-04 | Release date: | 2016-02-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Dissecting Therapeutic Resistance to ERK Inhibition. Mol.Cancer Ther., 15, 2016
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5HD4
| Dissecting Therapeutic Resistance to ERK Inhibition Rat Wild Type SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | Descriptor: | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... | Authors: | Jha, S, Morris, E.J, Hruza, A, Mansueto, M.S, Schroeder, G, Arbanas, J, McMasters, D, Restaino, C.R, Dayananth, R, Black, S, Elsen, N.L, Mannarino, A, Cooper, A, Fawell, S, Zawel, L, Jayaraman, L, Samatar, A.A. | Deposit date: | 2016-01-04 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Dissecting Therapeutic Resistance to ERK Inhibition. Mol.Cancer Ther., 15, 2016
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3QDE
| The structure of Cellobiose phosphorylase from Clostridium thermocellum in complex with phosphate | Descriptor: | Cellobiose phosphorylase, PHOSPHATE ION, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | Authors: | Bianchetti, C.M, Elsen, N.L, Horn, M.K, Fox, B.G, Phillips Jr, G.N. | Deposit date: | 2011-01-18 | Release date: | 2011-11-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of cellobiose phosphorylase from Clostridium thermocellum in complex with phosphate. Acta Crystallogr.,Sect.F, 67, 2011
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3RI7
| Toluene 4 monooxygenase HD Mutant G103L | Descriptor: | ACETATE ION, FE (III) ION, Toluene-4-monooxygenase system protein A, ... | Authors: | Bailey, L.J, Elsen, N.L, Fox, B.G. | Deposit date: | 2011-04-13 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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8V4X
| Structure of MALT1 in complex with an allosteric inhibitor | Descriptor: | Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea | Authors: | Judge, R.A, Pappano, W.N. | Deposit date: | 2023-11-29 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.486 Å) | Cite: | Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma. Mol.Cancer Ther., 23, 2024
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4DXD
| Staphylococcal Aureus FtsZ in complex with 723 | Descriptor: | 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Lu, J, Soisson, S.M. | Deposit date: | 2012-02-27 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics. Sci Transl Med, 4, 2012
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4P1B
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4P1C
| CRYSTAL STRUCTURE OF THE TOLUENE 4-MONOOXYGENASE HYDROXYLASE-FERREDOXIN C7S, C84A, C85A VARIANT ELECTRON-TRANSFER COMPLEX | Descriptor: | DI(HYDROXYETHYL)ETHER, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Acheson, J.F, Fox, B.G. | Deposit date: | 2014-02-25 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for biomolecular recognition in overlapping binding sites in a diiron enzyme system. Nat Commun, 5, 2014
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3Q2A
| Toluene 4 monooxygenase HD complex with inhibitor p-aminobenzoate | Descriptor: | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-AMINOBENZOIC ACID, FE (III) ION, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-19 | Release date: | 2011-12-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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3Q3O
| Toluene 4 monooxygenase HD complex with phenol | Descriptor: | FE (III) ION, PENTAETHYLENE GLYCOL, PHENOL, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-22 | Release date: | 2011-12-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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3Q14
| Toluene 4 monooxygenase HD Complex with p-cresol | Descriptor: | FE (III) ION, P-CRESOL, PENTAETHYLENE GLYCOL, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-16 | Release date: | 2011-12-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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3Q3N
| Toluene 4 monooxygenase HD complex with p-nitrophenol | Descriptor: | FE (III) ION, P-NITROPHENOL, PENTAETHYLENE GLYCOL, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-22 | Release date: | 2011-12-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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3Q3M
| Toluene 4 monooxygenase HD Complex with Inhibitor 4-Bromobenzoate | Descriptor: | 4-bromobenzoic acid, FE (III) ION, Toluene-4-monooxygenase system protein A, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-22 | Release date: | 2011-12-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.748 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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3RMK
| Toluene 4 monooxygenase H with 4-bromophenol | Descriptor: | 4-BROMOPHENOL, CALCIUM ION, FE (III) ION, ... | Authors: | Bailey, L.J, McCoy, J.G, Phillips Jr, G.N, Fox, B.G. | Deposit date: | 2011-04-21 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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