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2AY0
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BU of 2ay0 by Molmil
Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.
Descriptor: Bifunctional putA protein, CHLORIDE ION
Authors:Larson, J.D, Schuermann, J.P, Zhou, Y, Jenkins, J.L, Becker, D.F, Tanner, J.J.
Deposit date:2005-09-06
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.
Protein Sci., 15, 2006
1TJ1
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BU of 1tj1 by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-lactate
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-03
Release date:2004-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
1TJ0
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BU of 1tj0 by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) co-crystallized with L-lactate
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-02
Release date:2004-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
1TIW
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BU of 1tiw by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-Tetrahydro-2-furoic acid
Descriptor: Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE, TETRAHYDROFURAN-2-CARBOXYLIC ACID
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-02
Release date:2004-10-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
1TJ2
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BU of 1tj2 by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with acetate
Descriptor: ACETATE ION, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-03
Release date:2004-10-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
6ONO
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BU of 6ono by Molmil
Complex structure of WhiB1 and region 4 of SigA in C2221 space group
Descriptor: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
Authors:Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
Deposit date:2019-04-22
Release date:2019-11-27
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020
6ONU
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BU of 6onu by Molmil
Complex structure of WhiB1 and region 4 of SigA in P21 space group.
Descriptor: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
Authors:Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
Deposit date:2019-04-22
Release date:2019-11-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020
6UFP
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BU of 6ufp by Molmil
Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate and three cysteines (Cys46, Cys470, Cys638) modified to S,S-(2-HYDROXYETHYL)THIOCYSTEINE
Descriptor: (2S)-1,3-thiazolidine-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Campbell, A.C, Tanner, J.J.
Deposit date:2019-09-24
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.737 Å)
Cite:Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate.
Acs Chem.Biol., 15, 2020
8DKG
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BU of 8dkg by Molmil
Structure of PYCR1 Thr171Met variant complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isoform 3 of Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Meeks, K.R, Tanner, J.J.
Deposit date:2022-07-05
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Functional Impact of a Cancer-Related Variant in Human Delta 1 -Pyrroline-5-Carboxylate Reductase 1.
Acs Omega, 8, 2023
7MES
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BU of 7mes by Molmil
Structure of ALDH4A1 complexed with trans-4-Hydroxy-D-proline
Descriptor: (4S)-4-hydroxy-D-proline, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ...
Authors:Bogner, A.N, Stiers, K.M, Tanner, J.J.
Deposit date:2021-04-07
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline.
Protein Sci., 30, 2021
7MER
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BU of 7mer by Molmil
Structure of ALDH4A1 complexed with trans-4-Hydroxy-L-proline
Descriptor: 4-HYDROXYPROLINE, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ...
Authors:Bogner, A.N, Stiers, K.M, Tanner, J.J.
Deposit date:2021-04-07
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline.
Protein Sci., 30, 2021
4O8A
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BU of 4o8a by Molmil
First structure of a proline utilization A proline dehydrogenase domain
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2013-12-26
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein.
Nat.Struct.Biol., 10, 2003
3ITG
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BU of 3itg by Molmil
Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine
Descriptor: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J.
Deposit date:2009-08-28
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.
Biochemistry, 49, 2010
3HAZ
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BU of 3haz by Molmil
Crystal structure of bifunctional proline utilization A (PutA) protein
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2009-05-03
Release date:2010-02-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
2RBF
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BU of 2rbf by Molmil
Structure of the ribbon-helix-helix domain of Escherichia coli PutA (PutA52) complexed with operator DNA (O2)
Descriptor: Bifunctional protein putA, DNA (5'-D(*DTP*DT*DTP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DCP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DGP*DAP*DAP*DAP*DGP*DGP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DAP*DAP*DA)-3')
Authors:Tanner, J.J.
Deposit date:2007-09-18
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.
J.Mol.Biol., 381, 2008
5KF6
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BU of 5kf6 by Molmil
Structure of proline utilization A from Sinorhizobium meliloti complexed with L-tetrahydrofuroic acid and NAD+ in space group P21
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Tanner, J.J.
Deposit date:2016-06-12
Release date:2016-10-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Proline Utilization A (PutA) Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown Function.
J.Biol.Chem., 291, 2016
5KF7
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BU of 5kf7 by Molmil
Structure of proline utilization A from Sinorhizobium meliloti complexed with L-tetrahydrofuroic acid and NAD+ in space group P3121
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Tanner, J.J.
Deposit date:2016-06-12
Release date:2016-10-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Proline Utilization A (PutA) Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown Function.
J.Biol.Chem., 291, 2016
2JXH
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BU of 2jxh by Molmil
Solution Structure of DNA binding domain of Proline Utilization A (PutA) for Psuedomonas putida
Descriptor: Proline dehydrogenase
Authors:Halouska, S, Zhou, Y, Becker, D, Powers, R.
Deposit date:2007-11-19
Release date:2008-10-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Pseudomonas putida protein PpPutA45 and its DNA complex
Proteins, 75, 2008
2JXG
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BU of 2jxg by Molmil
Solution Structure of the DNA Binding domain of Proline Utilization A (PutA)
Descriptor: Proline dehydrogenase
Authors:Halouska, S, Zhou, Y, Becker, D, Powers, R.
Deposit date:2007-11-19
Release date:2008-02-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Pseudomonas putida protein PpPutA45 and its DNA complex
Proteins, 75, 2008
2JXI
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BU of 2jxi by Molmil
Solution structure of the DNA-binding domain of Pseudomonas putida Proline utilization A (putA) bound to GTTGCA DNA sequence
Descriptor: DNA (5'-D(*DAP*DAP*DAP*DGP*DGP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DCP*DTP*DTP*DT)-3'), Proline dehydrogenase
Authors:Halouska, S, Zhou, Y, Becker, D, Powers, R.
Deposit date:2007-11-19
Release date:2008-10-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the Pseudomonas putida protein PpPutA45 and its DNA complex
Proteins, 75, 2008
7NA0
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BU of 7na0 by Molmil
Structure of Geobacter sulfurreducens proline utilization A (PutA) variant A206W
Descriptor: 1,2-ETHANEDIOL, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Korasick, D.A.
Deposit date:2021-06-19
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of a ligand-modulated dynamic tunnel in bifunctional proline utilization A (PutA).
Arch.Biochem.Biophys., 712, 2021
7MYB
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BU of 7myb by Molmil
Structure of proline utilization A with tetrahydrothiophene-2-carboxylate bound in the proline dehydrogenase active site
Descriptor: (2R)-thiolane-2-carboxylic acid, (2S)-thiolane-2-carboxylic acid, Bifunctional protein PutA, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MY9
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BU of 7my9 by Molmil
Structure of proline utilization A with 1,3-dithiolane-2-carboxylate bound in the proline dehydrogenase active site
Descriptor: 1,3-dithiolane-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.628 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MYA
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BU of 7mya by Molmil
Structure of proline utilization A with the FAD covalently-modified by 1,3-dithiolane
Descriptor: Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MYC
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BU of 7myc by Molmil
Structure of proline utilization A with the FAD covalently modified by tetrahydrothiophene
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021

 

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