1MTW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mtw by Molmil](/molmil-images/mine/1mtw) | FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN | Descriptor: | (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid, CALCIUM ION, TRYPSIN | Authors: | Stubbs, M.T. | Deposit date: | 1997-05-16 | Release date: | 1997-11-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett., 375, 1995
|
|
3QT5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qt5 by Molmil](/molmil-images/mine/3qt5) | Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase | Descriptor: | Mevalonate diphosphate decarboxylase | Authors: | Barta, M.L, Skaff, A.D, McWhorter, W.J, Miziorko, H.M, Geisbrecht, B.V. | Deposit date: | 2011-02-22 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis. J.Biol.Chem., 286, 2011
|
|
3QUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qui by Molmil](/molmil-images/mine/3qui) | Crystal structure of Pseudomonas aeruginosa Hfq in complex with ADPNP | Descriptor: | ADENINE, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nikulin, A.D, Murina, V.N, Gabdulkhakov, A.G. | Deposit date: | 2011-02-24 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.933 Å) | Cite: | Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
|
|
1ADU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1adu by Molmil](/molmil-images/mine/1adu) | EARLY E2A DNA-BINDING PROTEIN | Descriptor: | ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, ZINC ION | Authors: | Tucker, P.A, Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C. | Deposit date: | 1995-05-11 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein. J.Mol.Biol., 257, 1996
|
|
1AJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1aj6 by Molmil](/molmil-images/mine/1aj6) | |
4GRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4grb by Molmil](/molmil-images/mine/4grb) | Casein kinase 2 (CK2) bound to inhibitor | Descriptor: | 5-(2-{[4-(dimethylcarbamoyl)phenyl]amino}-4-methoxypyrimidin-5-yl)thiophene-3-carboxylic acid, CHLORIDE ION, Casein kinase II subunit alpha | Authors: | Larsen, N.A, Dowling, J.E, Ferguson, A.D. | Deposit date: | 2012-08-24 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett, 4, 2013
|
|
4YG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yg2 by Molmil](/molmil-images/mine/4yg2) | X-ray crystal structur of Escherichia coli RNA polymerase sigma70 holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Murakami, K.S. | Deposit date: | 2015-02-25 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | X-ray crystal structure of Escherichia coli RNA polymerase sigma70 holoenzyme J. Biol. Chem., 288, 2013
|
|
1PHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pho by Molmil](/molmil-images/mine/1pho) | |
4Y7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y7b by Molmil](/molmil-images/mine/4y7b) | Factor Xa complex with GTC000441 | Descriptor: | 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopy rrolidin-3-yl}naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X | Authors: | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | Deposit date: | 2015-02-13 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Factor Xa complex with GTC000441 to be published
|
|
5I3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i3u by Molmil](/molmil-images/mine/5i3u) | |
1CDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cdp by Molmil](/molmil-images/mine/1cdp) | |
3SSF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ssf by Molmil](/molmil-images/mine/3ssf) | Crystal structure of RNA:DNA dodecamer corresponding to HIV-1 polypurine tract, at 1.6 A resolution. | Descriptor: | 5'-D(*CP*CP*TP*TP*TP*TP*CP*TP*TP*TP*TP*A)-3', 5'-R(*UP*AP*AP*AP*AP*GP*AP*AP*AP*AP*GP*G)-3', MAGNESIUM ION | Authors: | Drozdzal, P, Michalska, K, Kierzek, R, Lomozik, L, Jaskolski, M. | Deposit date: | 2011-07-08 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of an RNA/DNA dodecamer corresponding to the HIV-1 polypurine tract at 1.6 Angstrom resolution Acta Crystallogr.,Sect.D, 68, 2012
|
|
4J6X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6x by Molmil](/molmil-images/mine/4j6x) | |
1ANV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1anv by Molmil](/molmil-images/mine/1anv) | ADENOVIRUS 5 DBP/URANYL FLUORIDE SOAK | Descriptor: | ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, URANYL (VI) ION, ZINC ION | Authors: | Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C, Tucker, P.A. | Deposit date: | 1996-03-14 | Release date: | 1997-02-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Conformational change of the adenovirus DNA-binding protein induced by soaking crystals with K3UO2F5 solutions. Acta Crystallogr.,Sect.D, 52, 1996
|
|
1BBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bbu by Molmil](/molmil-images/mine/1bbu) | LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE | Descriptor: | LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE) | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | Deposit date: | 1998-04-24 | Release date: | 2000-11-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding. Biochemistry, 39, 2000
|
|
4J6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6y by Molmil](/molmil-images/mine/4j6y) | |
1QB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qb1 by Molmil](/molmil-images/mine/1qb1) | |
1QQL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qql by Molmil](/molmil-images/mine/1qql) | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Descriptor: | FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
|
|
3THK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3thk by Molmil](/molmil-images/mine/3thk) | Structure of SH3 chimera with a type II ligand linked to the chain C-terminal | Descriptor: | BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ... | Authors: | Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V. | Deposit date: | 2011-08-19 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide. J.Biomol.Struct.Dyn., 29, 2011
|
|
4J6W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6w by Molmil](/molmil-images/mine/4j6w) | Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP | Descriptor: | CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Nikulin, A.D, Murina, V, Lekontseva, N. | Deposit date: | 2013-02-12 | Release date: | 2013-07-31 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
|
|
1QQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qqk by Molmil](/molmil-images/mine/1qqk) | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR) | Descriptor: | FIBROBLAST GROWTH FACTOR 7 | Authors: | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | Deposit date: | 1999-06-07 | Release date: | 2000-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
|
|
1ER8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1er8 by Molmil](/molmil-images/mine/1er8) | THE ACTIVE SITE OF ASPARTIC PROTEINASES | Descriptor: | Endothiapepsin, H-77 | Authors: | Hemmings, A.M, Veerapandian, B, Szelke, M, Cooper, J.B, Blundell, T.L. | Deposit date: | 1989-10-16 | Release date: | 1991-10-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Active Site of Aspartic Proteinases FEBS Lett., 174, 1984
|
|
2IXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ixd by Molmil](/molmil-images/mine/2ixd) | Crystal structure of the putative deacetylase BC1534 from Bacillus cereus | Descriptor: | ACETATE ION, LMBE-RELATED PROTEIN, ZINC ION | Authors: | Fadouloglou, V.E, Bouriotis, V, Kokkinidis, M. | Deposit date: | 2006-07-07 | Release date: | 2007-07-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Bczbp, a Zinc-Binding Protein from Bacillus Cereus FEBS J., 274, 2007
|
|
1HIO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hio by Molmil](/molmil-images/mine/1hio) | HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN, ALPHA CARBONS ONLY | Descriptor: | HISTONE H2A, HISTONE H2B, HISTONE H3, ... | Authors: | Arents, G, Moudrianakis, E.N. | Deposit date: | 1991-09-19 | Release date: | 1998-11-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc.Natl.Acad.Sci.USA, 88, 1991
|
|
2IU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2iu0 by Molmil](/molmil-images/mine/2iu0) | crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase | Descriptor: | 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION | Authors: | Xu, L, Chong, Y, Hwang, I, Onofrio, A.D, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A. | Deposit date: | 2006-05-26 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structure-Based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase J.Biol.Chem., 282, 2007
|
|