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1RJG
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BU of 1rjg by Molmil
Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, carboxy methyl transferase for protein phosphatase 2A catalytic subunit
Authors:Leulliot, N, Quevillon-Cheruel, S, Sorel, I, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Blondeau, K, Bettache, N, Poupon, A, Janin, J, van Tilbeurgh, H.
Deposit date:2003-11-19
Release date:2003-12-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
J.Biol.Chem., 279, 2004
3PSN
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BU of 3psn by Molmil
Crystal structure of mouse VPS29 complexed with Mn2+
Descriptor: MANGANESE (II) ION, Vacuolar protein sorting-associated protein 29
Authors:Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B.
Deposit date:2010-12-02
Release date:2010-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
1RJD
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BU of 1rjd by Molmil
Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity
Descriptor: BETA-MERCAPTOETHANOL, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Leulliot, N, Quevillon-Cheruel, S, Sorel, I, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Blondeau, K, Bettache, N, Poupon, A, Janin, J, van Tilbeurgh, H.
Deposit date:2003-11-19
Release date:2003-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
J.Biol.Chem., 279, 2004
3RBF
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BU of 3rbf by Molmil
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form
Descriptor: Aromatic-L-amino-acid decarboxylase, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F.
Deposit date:2011-03-29
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
1RJE
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BU of 1rje by Molmil
Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity
Descriptor: BETA-MERCAPTOETHANOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Leulliot, N, Quevillon-Cheruel, S, Sorel, I, de La Sierra-Gallay, I.L, Collinet, B, Graille, M, Blondeau, K, Bettache, N, Poupon, A, Janin, J, van Tilbeurgh, H.
Deposit date:2003-11-19
Release date:2003-12-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity.
J.Biol.Chem., 279, 2004
1QFG
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BU of 1qfg by Molmil
E. COLI FERRIC HYDROXAMATE RECEPTOR (FHUA)
Descriptor: 3-HYDROXY-TETRADECANOIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, DIPHOSPHATE, ...
Authors:Ferguson, A.D, Welte, W, Hofmann, E, Lindner, B, Holst, O, Coulton, J.W, Diederichs, K.
Deposit date:1999-04-10
Release date:2000-07-26
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
Structure Fold.Des., 8, 2000
3RBL
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BU of 3rbl by Molmil
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form
Descriptor: CHLORIDE ION, aromatic L-amino acid decarboxylase
Authors:Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F.
Deposit date:2011-03-29
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RCH
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BU of 3rch by Molmil
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the open conformation with LLP and PLP bound to Chain-A and Chain-B respectively
Descriptor: PYRIDOXAL-5'-PHOSPHATE, aromatic L-amino acid decarboxylase
Authors:Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F.
Deposit date:2011-03-31
Release date:2011-10-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
4HV0
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BU of 4hv0 by Molmil
Structure and Function of AvtR, a Novel Transcriptional Regulator from a Hyperthermophilic Archaeal Lipothrixvirus
Descriptor: AvtR
Authors:Peixeiro, N, Keller, J, Collinet, B, Leulliot, N, Campanacci, V, Cortez, D, Cambillau, C, Nitta, K.R, Vincentelli, R, Forterre, P, Prangishvili, D, Sezonov, G, van Tilbeurgh, H.
Deposit date:2012-11-05
Release date:2012-11-21
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Function of AvtR, a Novel Transcriptional Regulator from a Hyperthermophilic Archaeal Lipothrixvirus.
J.Virol., 87, 2013
4I8A
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BU of 4i8a by Molmil
Alanine-glyoxylate aminotransferase variant S187F
Descriptor: GLYCEROL, Serine-pyruvate aminotransferase
Authors:Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M.
Deposit date:2012-12-03
Release date:2013-05-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
6N5X
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BU of 6n5x by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Z
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BU of 6n5z by Molmil
Crystal structure of the SNX5 PX domain in complex with the Sema4C
Descriptor: CHLORIDE ION, Sorting nexin-5,Semaphorin-4C
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Y
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BU of 6n5y by Molmil
Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
Descriptor: Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B, Paul, B, Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
3LH9
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BU of 3lh9 by Molmil
Crystal structure of mouse VPS26B(L197S/R199E) in spacegroup P41 21 2
Descriptor: Vacuolar protein sorting-associated protein 26B
Authors:Collins, B, Shaw, D, Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
3LH8
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BU of 3lh8 by Molmil
Crystal structure of mouse VPS26B in spacegroup P41 21 2
Descriptor: Vacuolar protein sorting-associated protein 26B
Authors:Collins, B, Shaw, D, Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
3LHA
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BU of 3lha by Molmil
Crystal structure of mouse VPS26B(R240S/G241A/E242S) in spacegroup P41 21 2
Descriptor: Vacuolar protein sorting-associated protein 26B
Authors:Collins, B, Shaw, D, Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
8CMX
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BU of 8cmx by Molmil
Structure of sphingosine-1-phosphate lyase (SPL) from Aspergillus fumigatus
Descriptor: Sphinganine-1-phosphate aldolase BST1, putative
Authors:Catalano, F, Pampalone, G.
Deposit date:2023-02-21
Release date:2024-01-03
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study.
Sci Rep, 13, 2023
6C3L
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BU of 6c3l by Molmil
Crystal structure of BCL6 BTB domain with compound 15f
Descriptor: B-cell lymphoma 6 protein, N-[2-(1H-indol-3-yl)ethyl]-N'-{3-[(4-methylpiperazin-1-yl)methyl]-1-[2-(morpholin-4-yl)-2-oxoethyl]-1H-indol-6-yl}thiourea
Authors:Linhares, B, Cheng, H, Cierpicki, T, Xue, F.
Deposit date:2018-01-10
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.46092153 Å)
Cite:Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
6C3N
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BU of 6c3n by Molmil
Crystal structure of BCL6 BTB domain in complex with compound 7CC5
Descriptor: B-cell lymphoma 6 protein, N-(2-phenylethyl)-N'-pyridin-3-ylthiourea
Authors:Linhares, B, Cheng, H, Xue, F, Cierpicki, T.
Deposit date:2018-01-10
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.53170586 Å)
Cite:Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
5TGH
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BU of 5tgh by Molmil
Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group P32
Descriptor: IncE, Sorting nexin-5
Authors:Collins, B, Paul, B.
Deposit date:2016-09-27
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the hijacking of endosomal sorting nexin proteins byChlamydia trachomatis.
Elife, 6, 2017
4QDH
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BU of 4qdh by Molmil
Crystal Structure of the C-terminal Domain of Mouse TLR9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
Authors:Collins, B.C, Wilson, I.A.
Deposit date:2014-05-13
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
4WCD
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BU of 4wcd by Molmil
Trypanosoma brucei PTR1 in complex with inhibitor 10
Descriptor: 5-(1H-benzotriazol-6-yl)-1,3,4-thiadiazol-2-amine, ACETATE ION, GLYCEROL, ...
Authors:Mangani, S, Di Pisa, F, Pozzi, C.
Deposit date:2014-09-04
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
6VTT
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BU of 6vtt by Molmil
Cryo-EM Structure of CAP256-VRC26.25 Fab bound to HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-02-13
Release date:2020-04-08
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.
Cell Rep, 31, 2020
8X1N
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BU of 8x1n by Molmil
Cryo-EM structure of human alpha-fetoprotein
Descriptor: Alpha-fetoprotein, PALMITIC ACID, ZINC ION, ...
Authors:Liu, Z.M, Li, M.S, Wu, C, Liu, K.
Deposit date:2023-11-08
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural characteristics of alpha-fetoprotein, including N-glycosylation, metal ion and fatty acid binding sites.
Commun Biol, 7, 2024
4W9Y
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BU of 4w9y by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a glutamyl sulfamide inhibitor CJC47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Pavlicek, J, Barinka, C.
Deposit date:2014-08-28
Release date:2015-09-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors.
J.Chem.Inf.Model., 2024

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