6RTS
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![BU of 6rts by Molmil](/molmil-images/mine/6rts) | Piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus complexed with NAD+ | Descriptor: | ACETATE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Hasse, D, Huelsemann, J, Carlsson, G, Andersson, I. | Deposit date: | 2019-05-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure and mechanism of piperideine-6-carboxylate dehydrogenase from Streptomyces clavuligerus. Acta Crystallogr D Struct Biol, 75, 2019
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3DCA
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![BU of 3dca by Molmil](/molmil-images/mine/3dca) | Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target | Descriptor: | RPA0582, SULFATE ION | Authors: | Sledz, P, Wang, S, Chruszcz, M, Yim, V, Kudritska, M, Evdokimova, E, Turk, D, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-06-03 | Release date: | 2008-08-05 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Crystal structure of the RPA0582- protein of unknown function from Rhodopseudomonas palustris- a structural genomics target To be Published
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6RQZ
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![BU of 6rqz by Molmil](/molmil-images/mine/6rqz) | GOLGI ALPHA-MANNOSIDASE II complex with Manno-epi-cyclophellitol aziridine | Descriptor: | (1~{R},2~{S},3~{R},4~{R},5~{S},6~{R})-5-azanyl-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Alpha-mannosidase 2, ... | Authors: | Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, Debets, M, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J. | Deposit date: | 2019-05-16 | Release date: | 2020-07-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. J.Am.Chem.Soc., 142, 2020
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6RRW
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![BU of 6rrw by Molmil](/molmil-images/mine/6rrw) | GOLGI ALPHA-MANNOSIDASE II in complex with (2R,3R,4R,5S)-1-(5-{[4-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy}pentyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol | Descriptor: | (2~{R},3~{R},4~{R},5~{S})-1-[5-[[4-(3,4-dihydro-2~{H}-1,5-benzodioxepin-7-yl)phenyl]methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, Alpha-mannosidase 2, ZINC ION | Authors: | Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, van Rijssel, E.R, Debets, M, Geurink, P.P, Ovaa, H, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J. | Deposit date: | 2019-05-20 | Release date: | 2020-07-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. J.Am.Chem.Soc., 142, 2020
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3H2B
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![BU of 3h2b by Molmil](/molmil-images/mine/3h2b) | Crystal structure of the SAM-dependent methyltransferase cg3271 from Corynebacterium glutamicum in complex with S-adenosyl-L-homocysteine and pyrophosphate. Northeast Structural Genomics Consortium Target CgR113A | Descriptor: | PYROPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-04-14 | Release date: | 2009-04-28 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Northeast Structural Genomics Consortium Target CgR113A To be published
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3D91
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![BU of 3d91 by Molmil](/molmil-images/mine/3d91) | Human renin in complex with remikiren | Descriptor: | DIMETHYL SULFOXIDE, Nalpha-[(2S)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-L-histidinamide, Renin | Authors: | Prade, L, Bezencon, O, Bur, D, Weller, T, Fischli, W, Remen, L. | Deposit date: | 2008-05-26 | Release date: | 2008-06-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human renin in complex with remikiren to be published
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3DDC
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![BU of 3ddc by Molmil](/molmil-images/mine/3ddc) | Crystal Structure of NORE1A in Complex with RAS | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Stieglitz, B, Bee, C, Schwarz, D, Yildiz, O, Moshnikova, A, Khokhlatchev, A, Herrmann, C. | Deposit date: | 2008-06-05 | Release date: | 2008-07-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Embo J., 27, 2008
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3VN4
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![BU of 3vn4 by Molmil](/molmil-images/mine/3vn4) | Crystal structure of the exosite-containing fragment of human ADAMTS13 (P475S mutant) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A disintegrin and metalloproteinase with thrombospondin motifs 13, ... | Authors: | Nakayama, D, Akiyama, M, Takeda, S, Kokame, K, Takagi, J, Miyata, T. | Deposit date: | 2011-12-21 | Release date: | 2012-12-26 | Last modified: | 2024-07-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure and enzymatic activity of an ADAMTS-13 mutant with the East Asian-specific P475S polymorphism. J.Thromb.Haemost., 11, 2013
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2LM2
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![BU of 2lm2 by Molmil](/molmil-images/mine/2lm2) | NMR structures of the transmembrane domains of the AChR b2 subunit | Descriptor: | Neuronal acetylcholine receptor subunit beta-2 | Authors: | Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. | Deposit date: | 2011-11-18 | Release date: | 2012-03-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structures of the transmembrane domains of the a4b2 nAChR. Biochim.Biophys.Acta, 1818, 2012
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2LQM
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![BU of 2lqm by Molmil](/molmil-images/mine/2lqm) | Solution Structures of RadA intein from Pyrococcus horikoshii | Descriptor: | Pho radA intein | Authors: | Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H. | Deposit date: | 2012-03-09 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein. J.Mol.Biol., 421, 2012
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3V7M
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![BU of 3v7m by Molmil](/molmil-images/mine/3v7m) | Crystal structure of monoclonal human anti-Rhesus D Fc IgG1 T125(YB2/0) in the presence of Zn2+ | Descriptor: | GLYCEROL, IMIDAZOLE, Ig gamma-1 chain C region, ... | Authors: | Menez, R, Stura, E.A, Bourel, D, Siberil, S, Jorieux, S, De Romeuf, C, Ducancel, F, Fridman, W.H, Teillaud, J.L. | Deposit date: | 2011-12-21 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Effect of zinc on human IgG1 and its Fc gamma R interactions. Immunol.Lett., 143, 2012
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3V8B
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![BU of 3v8b by Molmil](/molmil-images/mine/3v8b) | Crystal Structure of a 3-ketoacyl-ACP reductase from Sinorhizobium meliloti 1021 | Descriptor: | Putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier protein] reductase | Authors: | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-12-22 | Release date: | 2012-01-11 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of a 3-ketoacyl-ACP reductase from Sinorhizobium meliloti 1021 To be Published
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1DKE
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![BU of 1dke by Molmil](/molmil-images/mine/1dke) | NI BETA HEME HUMAN HEMOGLOBIN | Descriptor: | HEMOGLOBIN: ALPHA CHAIN, HEMOGLOBIN: BETA CHAIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Bruno, S, Bettatti, S, Mozzarelli, A, Bolognesi, M, Deriu, D, Rosano, C, Tsuneshige, A, Yonetani, T, Henry, E.R. | Deposit date: | 1999-12-07 | Release date: | 2000-05-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Oxygen binding by alpha(Fe2+)2beta(Ni2+)2 hemoglobin crystals. Protein Sci., 9, 2000
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3VNV
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![BU of 3vnv by Molmil](/molmil-images/mine/3vnv) | Complex structure of viral RNA polymerase II | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | Authors: | Takeshita, D, Tomita, K. | Deposit date: | 2012-01-18 | Release date: | 2012-08-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Mechanism for template-independent terminal adenylation activity of Q beta replicase Structure, 20, 2012
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7YXF
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![BU of 7yxf by Molmil](/molmil-images/mine/7yxf) | Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | Descriptor: | 1-(2-piperazin-1-ylethyl)-5-pyridin-4-yl-indole, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | Authors: | Snee, M, Katariya, M, Levy, C, Leys, D. | Deposit date: | 2022-02-16 | Release date: | 2023-03-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
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3DEC
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![BU of 3dec by Molmil](/molmil-images/mine/3dec) | Crystal structure of a glycosyl hydrolases family 2 protein from Bacteroides thetaiotaomicron | Descriptor: | Beta-galactosidase, POTASSIUM ION | Authors: | Kumaran, D, Bonanno, J, Romero, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-06-09 | Release date: | 2008-06-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of a Glycosyl Hydrolases Family 2 protein from Bacteroides thetaiotaomicron. To be Published
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6RH6
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![BU of 6rh6 by Molmil](/molmil-images/mine/6rh6) | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163 | Descriptor: | AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1 | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | Deposit date: | 2019-04-18 | Release date: | 2019-09-04 | Method: | SOLUTION NMR | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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3DJB
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![BU of 3djb by Molmil](/molmil-images/mine/3djb) | Crystal structure of a HD-superfamily hydrolase (BT9727_1981) from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR114 | Descriptor: | Hydrolase, HD family, MAGNESIUM ION | Authors: | Forouhar, F, Su, M, Seetharaman, J, Vorobiev, S.M, Janjua, H, Fang, Y, Xiao, R, Cunningham, K, Maglaqui, M, Owen, L.A, Wang, D, Baran, M.C, Liu, J, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-06-23 | Release date: | 2008-08-19 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a HD-superfamily hydrolase (BT9727_1981) from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR114 To be Published
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3VCA
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![BU of 3vca by Molmil](/molmil-images/mine/3vca) | Quaternary Ammonium Oxidative Demethylation: X-ray Crystallographic, Resonance Raman and UV-visible Spectroscopic Analysis of a Rieske-type Demethylase | Descriptor: | FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | Authors: | Daughtry, K.D, Xiao, Y, Stoner-Ma, D, Cho, E, Orville, A.M, Liu, P, Allen, K.N. | Deposit date: | 2012-01-03 | Release date: | 2012-02-08 | Last modified: | 2012-02-22 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Quaternary Ammonium Oxidative Demethylation: X-ray Crystallographic, Resonance Raman, and UV-Visible Spectroscopic Analysis of a Rieske-Type Demethylase. J.Am.Chem.Soc., 134, 2012
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3DG9
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![BU of 3dg9 by Molmil](/molmil-images/mine/3dg9) | Crystal Structure of Malonate Decarboxylase from Bordatella bronchiseptica | Descriptor: | Arylmalonate decarboxylase, PHOSPHATE ION | Authors: | Okrasa, K, Levy, C, Baudendistel, N, Leys, D, Micklefield, J. | Deposit date: | 2008-06-13 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and Mechanism of an Unusual Malonate Decarboxylase and Related Racemases. Chemistry, 14, 2008
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3GLX
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![BU of 3glx by Molmil](/molmil-images/mine/3glx) | Crystal Structure Analysis of the DtxR(E175K) complexed with Ni(II) | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | Authors: | D'Aquino, J.A, Denninger, A, Moulin, A, D'Aquino, K.E, Ringe, D. | Deposit date: | 2009-03-12 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Decreased sensitivity to changes in the concentration of metal ions as the basis for the hyperactivity of DtxR(E175K). J.Mol.Biol., 390, 2009
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7Z9K
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![BU of 7z9k by Molmil](/molmil-images/mine/7z9k) | E.coli gyrase holocomplex with 217 bp DNA and Albi-1 (site TG) | Descriptor: | 4-[[4-[[5-[[(2S)-2-[[5-[(4-cyanophenyl)carbonylamino]pyridin-2-yl]carbonylamino]-3-(1H-1,2,3-triazol-4-yl)propanoyl]amino]pyridin-2-yl]carbonylamino]-2-oxidanyl-3-propan-2-yloxy-phenyl]carbonylamino]benzoic acid, DNA (5'-D(*AP*AP*TP*CP*AP*CP*CP*CP*GP*CP*AP*CP*AP*GP*AP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*TP*TP*AP*TP*GP*CP*CP*TP*GP*AP*TP*TP*CP*T)-3'), ... | Authors: | Ghilarov, D, Heddle, J.G.H. | Deposit date: | 2022-03-21 | Release date: | 2023-03-08 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin. Nat Catal, 6, 2023
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7Z5E
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![BU of 7z5e by Molmil](/molmil-images/mine/7z5e) | VP2-only capsid of MVM D263A mutant | Descriptor: | Capsid protein VP1 | Authors: | Luque, D, Ortega-Esteban, A, Valbuena, A, Vilas, J.L, Rodriguez-Huete, A, Mateu, M.G, Caston, J.R. | Deposit date: | 2022-03-09 | Release date: | 2023-03-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J.Mol.Biol., 435, 2023
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7Z5F
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![BU of 7z5f by Molmil](/molmil-images/mine/7z5f) | VP2-only capsid of MVM D263A mutant | Descriptor: | Capsid protein VP1 | Authors: | Luque, D, Ortega-Esteban, A, Valbuena, A, Vilas, J.L, Rodriguez-Huete, A, Mateu, M.G, Caston, J.R. | Deposit date: | 2022-03-09 | Release date: | 2023-03-08 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Equilibrium Dynamics of a Biomolecular Complex Analyzed at Single-amino Acid Resolution by Cryo-electron Microscopy. J.Mol.Biol., 435, 2023
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3GSV
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![BU of 3gsv by Molmil](/molmil-images/mine/3gsv) | Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5Q peptide variant | Descriptor: | Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant M5Q (NLVPQVATV), ... | Authors: | Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | Deposit date: | 2009-03-27 | Release date: | 2009-08-04 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
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