8F4O
 
 | | Apo structure of the TPP riboswitch aptamer domain | | Descriptor: | IRIDIUM HEXAMMINE ION, TETRAETHYLENE GLYCOL, TPP riboswitch aptamer domain, ... | | Authors: | Lee, H.-K, Wang, Y.-X, Stagno, J.R. | | Deposit date: | 2022-11-11 | | Release date: | 2023-05-17 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state.
Structure, 31, 2023
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5W0T
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7MK7
 | | Augmentor domain of augmentor-beta | | Descriptor: | ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J. | | Deposit date: | 2021-04-21 | | Release date: | 2021-11-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.42815185 Å) | | Cite: | Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
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8G4U
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2K3O
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8C44
 | | HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Raghavan, S.S.R, Lavstsen, T, Wang, K.T. | | Deposit date: | 2022-12-31 | | Release date: | 2023-08-16 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
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8GKA
 | | Human TRPV3 tetramer structure, closed conformation | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | | Authors: | Lansky, S, Betancourt, J.M, Scheuring, S. | | Deposit date: | 2023-03-17 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
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8GKG
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7WQV
 | | Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ... | | Authors: | Zha, J, Meng, L, Zhang, X, Li, D. | | Deposit date: | 2022-01-26 | | Release date: | 2023-01-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy.
Plos Pathog., 19, 2023
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8C3Y
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7LDG
 | | Crystal structure of the MEILB2-BRCA2 complex | | Descriptor: | Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein | | Authors: | Nandakumar, J, Pendlebury, D.F. | | Deposit date: | 2021-01-13 | | Release date: | 2021-08-11 | | Last modified: | 2021-08-25 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites.
Nat.Struct.Mol.Biol., 28, 2021
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7DK2
 | | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW07 heavy chain, MW07 light chain, ... | | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M, Chen, S. | | Deposit date: | 2020-11-22 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Architectural versatility of spike neutralization by a SARS-CoV-2 antibody
To Be Published
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2K3Q
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2K3P
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7MWH
 | | Crystal structure of BAZ2A with DNA | | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2021-05-17 | | Release date: | 2022-08-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Crystal structure of the BAZ2B TAM domain.
Heliyon, 8, 2022
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7E12
 | | Crystal structure of PKAc-A11E complex | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, THR-ARG-SER-GLU-ILE-ARG-ARG-ALA-SER-THR-ILE-GLU, ... | | Authors: | Qin, J, Lin, L, Yuchi, Z. | | Deposit date: | 2021-01-28 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.796 Å) | | Cite: | Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy.
Elife, 11, 2022
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7E0Z
 | | Crystal structure of PKAc-PLN complex | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLN, ... | | Authors: | Qin, J, Yuchi, Z. | | Deposit date: | 2021-01-28 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.162 Å) | | Cite: | Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy.
Elife, 11, 2022
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7E11
 | | Crystal structure of PKAc-PLN R9C complex | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLN, ... | | Authors: | Qin, J, Lin, L, Yuchi, Z. | | Deposit date: | 2021-01-28 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.43 Å) | | Cite: | Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy.
Elife, 11, 2022
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2K3N
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7LRZ
 | | Structure of the Human ALK GRD | | Descriptor: | ALK tyrosine kinase receptor | | Authors: | Stayrook, S, Li, T, Klein, D.E. | | Deposit date: | 2021-02-17 | | Release date: | 2021-11-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
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6UM5
 | | Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Acharya, P, Henderson, R.C, Saunders, K.O, Haynes, B.F. | | Deposit date: | 2019-10-09 | | Release date: | 2019-12-18 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
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8JAR
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | Authors: | Zhao, S, Zhang, K, Xu, C. | | Deposit date: | 2023-05-07 | | Release date: | 2023-10-18 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAL
 | | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | Authors: | Zhao, S, Zhang, K, Xu, C. | | Deposit date: | 2023-05-06 | | Release date: | 2023-10-18 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Zhao, S, Zhang, K, Xu, C. | | Deposit date: | 2023-05-07 | | Release date: | 2023-10-18 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
 | | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Zhao, S, Zhang, K, Xu, C. | | Deposit date: | 2023-05-06 | | Release date: | 2023-10-18 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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