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8HQ4
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BU of 8hq4 by Molmil
B27 in complex with CRM1-Ran-RanBP1
Descriptor: 3-[(4-fluorophenyl)carbonylamino]-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ...
Authors:Lei, Y, Sun, Q.
Deposit date:2022-12-13
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:B27 in complex with CRM1-Ran-RanBP1
To Be Published
6JLH
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BU of 6jlh by Molmil
Structure of SCGN in complex with a Snap25 peptide
Descriptor: CALCIUM ION, CHLORIDE ION, Secretagogin, ...
Authors:Qin, J, Sun, Q, Jia, D.
Deposit date:2019-03-05
Release date:2020-03-11
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural and mechanistic insights into secretagogin-mediated exocytosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7F68
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BU of 7f68 by Molmil
Crystal structure of N-ras S89D
Descriptor: GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Li, Y, Sun, Q.
Deposit date:2021-06-24
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal structure of N-ras S89D
To Be Published
6KN0
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BU of 6kn0 by Molmil
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
Descriptor: Caspase-1, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-02
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.793 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KN1
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BU of 6kn1 by Molmil
P20/P12 of caspase-11 mutant C254A
Descriptor: Caspase-4
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-02
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMZ
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BU of 6kmz by Molmil
caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
Descriptor: Caspase-4, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMT
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BU of 6kmt by Molmil
P32 of caspase-11 mutant C254A
Descriptor: Caspase-4
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMU
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BU of 6kmu by Molmil
P22/P10 complex of caspase-11 mutant C254A
Descriptor: Caspase-4
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMV
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BU of 6kmv by Molmil
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
Descriptor: Caspase-4, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
7CT1
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BU of 7ct1 by Molmil
Crystal structure of Snx27 FERM domain in complex with a DLF motif
Descriptor: Fusion protein Sorting nexin-27 and DLF motif, GLYCEROL
Authors:Hu, W, Da, J, Sun, Q.
Deposit date:2020-08-17
Release date:2021-08-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Crystal structure of Snx27 FERM domain in complex with a DLF motif
To Be Published
7XLT
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BU of 7xlt by Molmil
Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids
Descriptor: DNA, RNA, S9.6 Fab HC, ...
Authors:Li, Q, Lin, C, Luo, Z, Li, H, Li, X, Sun, Q.
Deposit date:2022-04-22
Release date:2022-05-25
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids.
J Genet Genomics, 49, 2022
7XPI
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BU of 7xpi by Molmil
Structure of a oxidoreductase
Descriptor: Apoptosis inducing factor mitochondria associated 2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lv, Y, Sun, Q, Wang, Q, Zhu, D.
Deposit date:2022-05-04
Release date:2023-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into FSP1 catalysis and ferroptosis inhibition.
Nat Commun, 14, 2023
3COG
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BU of 3cog by Molmil
Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine
Descriptor: (2S)-2-aminopent-4-enoic acid, Cystathionine gamma-lyase, DI(HYDROXYETHYL)ETHER, ...
Authors:Collins, R, Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Schuler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Sagermark, J, Busam, R.D, Welin, M, Weigelt, J, Wikstrom, M, Structural Genomics Consortium (SGC)
Deposit date:2008-03-28
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.
J.Biol.Chem., 284, 2009
2NMP
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BU of 2nmp by Molmil
Crystal structure of human Cystathionine gamma lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van-den-Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2006-10-23
Release date:2006-11-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
7M9F
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BU of 7m9f by Molmil
Structure of the wild-type native full-length HIV-1 capsid protein in complex with ZW-1261
Descriptor: HIV-1 capsid protein, IODIDE ION, N-(4-chlorophenyl)-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide
Authors:Kirby, K.A, Sarafianos, S.G.
Deposit date:2021-03-31
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation.
Viruses, 13, 2021
5WWN
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BU of 5wwn by Molmil
Crystal structure of Tsr1
Descriptor: Ribosome biogenesis protein TSR1, SULFATE ION
Authors:Ye, K, Wang, B.
Deposit date:2017-01-03
Release date:2017-06-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WXM
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BU of 5wxm by Molmil
Crystal structure of the Imp3 and Mpp10 complex
Descriptor: SULFATE ION, U3 small nucleolar RNA-associated protein MPP10, U3 small nucleolar ribonucleoprotein protein IMP3
Authors:Ye, K, Zheng, S.
Deposit date:2017-01-07
Release date:2017-06-28
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WWO
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BU of 5wwo by Molmil
Crystal structure of Enp1
Descriptor: Essential nuclear protein 1, Protein LTV1
Authors:Ye, K, Zhang, W.
Deposit date:2017-01-03
Release date:2017-06-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WWM
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BU of 5wwm by Molmil
Crystal structure of the TPR domain of Rrp5
Descriptor: SULFATE ION, rRNA biogenesis protein RRP5
Authors:Ye, K, Chen, X.
Deposit date:2017-01-03
Release date:2017-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Correction: Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WYL
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BU of 5wyl by Molmil
Crystal structure of Chaetomium thermophilum Utp10 N-terminal domain in complex with Utp17 C-terminal helices
Descriptor: Putative uncharacterized protein
Authors:Chen, R, Zhu, X, Ye, K.
Deposit date:2017-01-13
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.638 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WXL
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BU of 5wxl by Molmil
Crystal structure of the Rrs1 and Rpf2 complex
Descriptor: Regulator of ribosome biosynthesis, Ribosome biogenesis protein RPF2
Authors:Ye, K, Zheng, S.
Deposit date:2017-01-07
Release date:2017-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
5WY3
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BU of 5wy3 by Molmil
Crystal structure of Chaetomium thermophilum Utp10 middle domain
Descriptor: Putative uncharacterized protein
Authors:Chen, R, Zhu, X, Ye, K.
Deposit date:2017-01-10
Release date:2017-06-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
6J24
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BU of 6j24 by Molmil
Crystal structure of a SAM-dependent methyltransferase LepI in complex with its substrate
Descriptor: (3~{S},4'~{R},4'~{a}~{S},6'~{R},8'~{a}~{S})-4',6'-dimethyl-5-phenyl-spiro[1~{H}-pyridine-3,5'-2,3,4,4~{a},6,8~{a}-hexahydro-1~{H}-naphthalene]-2,4-dione, O-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Qiu, S, Wei, C.
Deposit date:2018-12-30
Release date:2019-05-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.244 Å)
Cite:Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019
6J1O
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BU of 6j1o by Molmil
Crystal structure of a SAM-dependent methyltransferase LepI from Aspergillus flavus
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, O-methyltransferase lepI, S-ADENOSYLMETHIONINE
Authors:Qiu, S, Wei, C.
Deposit date:2018-12-28
Release date:2019-05-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019
6J46
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BU of 6j46 by Molmil
LepI-SAH complex structure
Descriptor: O-methyltransferase lepI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Qiu, S, Wei, C.
Deposit date:2019-01-08
Release date:2019-05-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.621 Å)
Cite:Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019

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