7M9F

Structure of the wild-type native full-length HIV-1 capsid protein in complex with ZW-1261

Summary for 7M9F

• Entry DOI: 10.2210/pdb7m9f/pdb
• Descriptor: HIV-1 capsid protein, N-(4-chlorophenyl)-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide, IODIDE ION, ... (4 entities in total)
• Functional Keywords: hiv-1 capsid protein, hexamer, ca-targeting antiviral, viral protein
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 1
• Total formula weight: 26726.89

Authors

Kirby, K.A.,Sarafianos, S.G. (deposition date: 2021-03-31, release date: 2022-04-06, Last modification date: 2023-10-18)

• Primary citation: Sun, Q.,Levy, R.M.,Kirby, K.A.,Wang, Z.,Sarafianos, S.G.,Deng, N.; Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation.; Viruses, 13:-, 2021; PubMed: 34063519; DOI: 10.3390/v13050920

Experimental method

X-RAY DIFFRACTION (2.7 Å)