1IA8
 
 | | THE 1.7 A CRYSTAL STRUCTURE OF HUMAN CELL CYCLE CHECKPOINT KINASE CHK1 | | Descriptor: | CHK1 CHECKPOINT KINASE, SULFATE ION | | Authors: | Chen, P, Luo, C, Deng, Y, Ryan, K, Register, J, Margosiak, S, Tempczyk-Russell, A, Nguyen, B, Myers, P, Lundgren, K, Chen Kan, C.-C, O'Connor, P.M. | | Deposit date: | 2001-03-22 | | Release date: | 2001-04-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation.
Cell(Cambridge,Mass.), 100, 2000
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8IAZ
 | | Cryo-EM structure of the ISFba1 TnpB-reRNA-dsDNA complex | | Descriptor: | DNA (5'-D(P*AP*CP*AP*TP*GP*GP*AP*CP*CP*AP*TP*CP*AP*GP*CP*TP*CP*CP*TP*AP*AP*TP*GP*G)-3'), DNA (5'-D(P*CP*CP*AP*TP*TP*AP*GP*GP*AP*GP*CP*TP*GP*AP*TP*G)-3'), RNA (207-MER), ... | | Authors: | Yin, M, Zhou, F, Zhu, Y, Huang, Z. | | Deposit date: | 2023-02-09 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Discovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs.
Cell Res., 34, 2024
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5FLK
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2K1V
 | | R3/I5 relaxin chimera | | Descriptor: | Insulin-like peptide INSL5, Relaxin-3 | | Authors: | Rosengren, K, Haugaard-Jonsson, L.M. | | Deposit date: | 2008-03-17 | | Release date: | 2008-04-08 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Structure of the R3/I5 Chimeric Relaxin Peptide, a Selective GPCR135 and GPCR142 Agonist.
J.Biol.Chem., 283, 2008
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2LR9
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2KNM
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2LEW
 | | Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4 | | Descriptor: | Alpha-defensin 4 | | Authors: | Rosengren, K, Andersson, H.S, Haugaard-Kedstrom, L.M, Bengtsson, E, Daly, N.L, Craik, D.J. | | Deposit date: | 2011-06-24 | | Release date: | 2012-05-16 | | Last modified: | 2013-06-19 | | Method: | SOLUTION NMR | | Cite: | The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
Amino Acids, 43, 2012
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2MFS
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2MXM
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2KNN
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2LEY
 | | Solution structure of (R7G)-Crp4 | | Descriptor: | Alpha-defensin 4 | | Authors: | Rosengren, K, Andersson, H.S, Haugaard-Kedstrom, L.M, Bengtsson, E, Daly, N.L, Figueredo, S.M, Qu, X, Craik, D.J, Ouellette, A.J. | | Deposit date: | 2011-06-26 | | Release date: | 2012-05-16 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
Amino Acids, 43, 2012
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8D8R
 | | SARS-CoV-2 Spike RBD in complex with DMAb 2196 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ... | | Authors: | Du, J, Cui, J, Pallesen, J. | | Deposit date: | 2022-06-08 | | Release date: | 2022-10-19 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
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8D8Q
 | | SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ... | | Authors: | Du, J, Cui, J, Pallesen, J. | | Deposit date: | 2022-06-08 | | Release date: | 2022-10-19 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
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4E7T
 | | The structure of T6 bovine insulin | | Descriptor: | Insulin A chain, Insulin B chain, ZINC ION | | Authors: | Harris, P, Frankaer, C.G, Knudsen, M.V. | | Deposit date: | 2012-03-19 | | Release date: | 2012-04-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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4E7U
 | | The structure of T3R3 bovine insulin | | Descriptor: | Insulin A chain, Insulin B chain, THIOCYANATE ION, ... | | Authors: | Harris, P, Frankaer, C.G, Knudsen, M.V. | | Deposit date: | 2012-03-19 | | Release date: | 2012-04-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
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5WTI
 | | Crystal structure of the CRISPR-associated protein in complex with crRNA and DNA | | Descriptor: | CRISPR-associated protein, DNA (28-MER), DNA (5'-D(P*GP*TP*GP*TP*GP*GP*AP*TP*TP*CP*CP*G)-3'), ... | | Authors: | Wu, D, Guan, X, Zhu, Y, Huang, Z. | | Deposit date: | 2016-12-13 | | Release date: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.682 Å) | | Cite: | Structural basis of stringent PAM recognition by CRISPR-C2c1 in complex with sgRNA
Cell Res., 27, 2017
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4UXZ
 | | Structure of delta7-DgkA-syn in 7.9 MAG to 2.18 angstrom resolution | | Descriptor: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ACETATE ION, ... | | Authors: | Li, D, Howe, N, Caffrey, M. | | Deposit date: | 2014-08-27 | | Release date: | 2015-09-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
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4MBJ
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6IUF
 | | Crystal structure of Anti-CRISPR protein AcrVA5 | | Descriptor: | ACETYL COENZYME *A, GLYCEROL, protein-a | | Authors: | Dong, L, Guan, X, Zhu, Y, Huang, Z. | | Deposit date: | 2018-11-28 | | Release date: | 2019-04-10 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.052 Å) | | Cite: | An anti-CRISPR protein disables type V Cas12a by acetylation.
Nat. Struct. Mol. Biol., 26, 2019
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6IV6
 | | Cryo-EM structure of AcrVA5-acetylated MbCas12a in complex with crRNA | | Descriptor: | RNA (59-MER), nuclease | | Authors: | Dong, L, Li, N, Guan, X, Zhu, Y, Gao, N, Huang, Z. | | Deposit date: | 2018-12-02 | | Release date: | 2019-04-10 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | An anti-CRISPR protein disables type V Cas12a by acetylation.
Nat. Struct. Mol. Biol., 26, 2019
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8INP
 | | A reversible glycosyltransferase of tectorigenin - Bc7OUGT | | Descriptor: | Bc7OUGT, URIDINE-5'-DIPHOSPHATE, beta-D-glucopyranose | | Authors: | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | | Deposit date: | 2023-03-10 | | Release date: | 2023-08-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
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8ITA
 | | A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin | | Descriptor: | 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE | | Authors: | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
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7EDO
 | | First insight into marsupial MHC I peptide presentation: immune features of lower mammals paralleled with bats | | Descriptor: | Beta-2-microglobulin, CYS-ASN-VAL-THR-LEU-ASN-TYR-PRO, MHC class I antigen | | Authors: | Wang, P.Y, Yue, C, Lu, D, Liu, K.F, Liu, S, Yao, S.J, Chai, Y, Qi, J.X, Lou, Y.L, Sun, Z.Y, Gao, G.F, Liu, W.J. | | Deposit date: | 2021-03-16 | | Release date: | 2021-08-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats.
J Immunol., 207, 2021
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7DHT
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8P8T
 | | Ex vivo Ym2 crystal structure | | Descriptor: | Chitinase-like protein 4, GLYCEROL | | Authors: | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N. | | Deposit date: | 2023-06-02 | | Release date: | 2024-01-17 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
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