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8DUE
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BU of 8due by Molmil
Open state of T4 bacteriophage gp41 hexamer bound with single strand DNA
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ...
Authors:Feng, X, Li, H.
Deposit date:2022-07-27
Release date:2023-06-14
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DWJ
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BU of 8dwj by Molmil
Primase of mutant bacteriophage T4 primosome with single strand DNA/RNA primer hybrid in primer exiting state
Descriptor: DNA (70-MER), DNA primase, RNA(5'-ppp-GCCGA-3'), ...
Authors:Feng, X, Li, H.
Deposit date:2022-08-01
Release date:2023-06-14
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
3UBU
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BU of 3ubu by Molmil
Crystal structure of agkisacucetin, a GpIb-binding snaclec (snake C-type lectin) that inhibits platelet
Descriptor: Agglucetin subunit alpha-1, Agglucetin subunit beta-2, GLYCEROL, ...
Authors:Gao, Y, Ge, H, Chen, H, Li, H, Liu, Y, Niu, L, Teng, M.
Deposit date:2011-10-25
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of agkisacucetin, a Gpib-binding snake C-type lectin that inhibits platelet adhesion and aggregation.
Proteins, 2012
4WLG
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BU of 4wlg by Molmil
crystal structure of mouse Xyloside xylosyltransferase 1, apo form
Descriptor: SULFATE ION, Xyloside xylosyltransferase 1
Authors:Yu, H, Li, H.
Deposit date:2014-10-07
Release date:2015-11-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WMB
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BU of 4wmb by Molmil
crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, acceptor ligand and UDP
Descriptor: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
Authors:Yu, H, Li, H.
Deposit date:2014-10-08
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
4WMK
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BU of 4wmk by Molmil
Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex II)
Descriptor: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ...
Authors:Yu, H, Li, H.
Deposit date:2014-10-09
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
Nat.Chem.Biol., 11, 2015
1RS8
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BU of 1rs8 by Molmil
Bovine endothelial NOS heme domain with D-lysine-D-nitroarginine amide bound
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
Authors:Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
1RS6
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BU of 1rs6 by Molmil
Rat neuronal NOS heme domain with D-lysine-D-nitroarginine amide bound
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
Authors:Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1I83
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BU of 1i83 by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE)
Descriptor: ACETATE ION, GLYCEROL, N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE, ...
Authors:Raman, C.S, Li, H, Martasek, P, Babu, B.R, Griffith, O.W, Masters, B.S.S, Poulos, T.L.
Deposit date:2001-03-12
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
1RS7
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BU of 1rs7 by Molmil
Rat neuronal NOS heme domain with D-phenylalanine-D-nitroarginine amide bound
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
Authors:Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1RS9
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BU of 1rs9 by Molmil
Bovine endothelial NOS heme domain with D-phenylalanine-D-nitroarginine amide bound
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
Authors:Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
5Z93
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BU of 5z93 by Molmil
Crystal Structure of SIRT3 in complex with H3K9bhb peptide
Descriptor: Gene for histone H3 (germline gene), NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ...
Authors:Zhang, X, Li, H.
Deposit date:2018-02-02
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.945 Å)
Cite:Crystal Structure of SIRT3 in complex with H3K9bhb peptide
To Be Published
6AYF
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BU of 6ayf by Molmil
TRPML3/ML-SA1 complex at pH 7.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-3
Authors:Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J.
Deposit date:2017-09-08
Release date:2017-11-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
6WPG
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BU of 6wpg by Molmil
Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins
Descriptor: 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4
Authors:Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N.
Deposit date:2020-04-27
Release date:2020-08-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.283 Å)
Cite:Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
6AYG
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BU of 6ayg by Molmil
Human Apo-TRPML3 channel at pH 4.8
Descriptor: Mucolipin-3
Authors:Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J.
Deposit date:2017-09-08
Release date:2017-11-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
6AYE
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BU of 6aye by Molmil
Human apo-TRPML3 channel at pH 7.4
Descriptor: Mucolipin-3
Authors:Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J.
Deposit date:2017-09-08
Release date:2017-11-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017
6OWU
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BU of 6owu by Molmil
THE PRP8 INTEIN OF CRYPTOCOCCUS NEOFORMANS in complex with Zn2+
Descriptor: PRP8 protein, ZINC ION
Authors:Li, Z, Li, H.
Deposit date:2019-05-11
Release date:2019-10-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.
Plos Biol., 17, 2019
2AFF
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BU of 2aff by Molmil
The solution structure of the Ki67FHA/hNIFK(226-269)3P complex
Descriptor: Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein
Authors:Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D.
Deposit date:2005-07-25
Release date:2005-10-25
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nat.Struct.Mol.Biol., 12, 2005
6VSI
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BU of 6vsi by Molmil
Crystal structure of FKBP12 of Candida auris
Descriptor: Peptidylprolyl isomerase, SULFATE ION
Authors:Li, Z, Li, H, Hernandez, G, LeMaster, D.
Deposit date:2020-02-11
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris.
Biochem.Biophys.Res.Commun., 525, 2020
6E15
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BU of 6e15 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
6E14
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BU of 6e14 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
1NDG
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BU of 1ndg by Molmil
Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme
Descriptor: ACETIC ACID, Lysozyme C, antibody kappa light chain, ...
Authors:Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J.
Deposit date:2002-12-09
Release date:2003-06-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
1HQR
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BU of 1hqr by Molmil
CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II
Descriptor: HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ...
Authors:Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R.
Deposit date:2000-12-19
Release date:2001-01-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
6W6G
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BU of 6w6g by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-16
Release date:2021-03-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
6W6E
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BU of 6w6e by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined ClpB middle domain and a DnaK nucleotide binding domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021

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