6W6G

The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate

Summary for 6W6G

• Entry DOI: 10.2210/pdb6w6g/pdb
• EMDB information: 21553 21554 21555 21556 21557
• Descriptor: Chaperone protein ClpB, Substrate, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: clpb/dnak, protein aggregates, unfold, refold protein, chaperone
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 7
• Total formula weight: 565043.03

Authors

Yin, Y.,Li, H. (deposition date: 2020-03-16, release date: 2021-03-17, Last modification date: 2021-09-29)

• Primary citation: Yin, Y.,Feng, X.,Yu, H.,Fay, A.,Kovach, A.,Glickman, M.S.,Li, H.; Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.; Cell Rep, 35:109166-109166, 2021; PubMed: 34038719; DOI: 10.1016/j.celrep.2021.109166

Experimental method

ELECTRON MICROSCOPY (3.1 Å)