7ESZ
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![BU of 7esz by Molmil](/molmil-images/mine/7esz) | Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB with Mn2+ from wPip | Descriptor: | BACTERIA FACTOR A, BACTERIA FACTOR B, MANGANESE (II) ION | Authors: | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | Deposit date: | 2021-05-12 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.476 Å) | Cite: | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET0
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![BU of 7et0 by Molmil](/molmil-images/mine/7et0) | Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB from wPip | Descriptor: | Bacteria factor A, Bacteria factor B | Authors: | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | Deposit date: | 2021-05-12 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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3C7K
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![BU of 3c7k by Molmil](/molmil-images/mine/3c7k) | Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(o) subunit alpha, MAGNESIUM ION, ... | Authors: | Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B. | Deposit date: | 2008-02-07 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C7L
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![BU of 3c7l by Molmil](/molmil-images/mine/3c7l) | Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation | Descriptor: | Regulator of G-protein signaling 16 | Authors: | Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B. | Deposit date: | 2008-02-07 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation. Proc.Natl.Acad.Sci.Usa, 105, 2008
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6OMO
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![BU of 6omo by Molmil](/molmil-images/mine/6omo) | Human BMP6 homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 6, ... | Authors: | Juo, Z.S, Seeherman, H. | Deposit date: | 2019-04-19 | Release date: | 2019-05-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med, 11, 2019
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6OMN
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![BU of 6omn by Molmil](/molmil-images/mine/6omn) | Glycosylated BMP2 homodimer | Descriptor: | Bone morphogenetic protein 2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Juo, Z.S, Seeherman, H. | Deposit date: | 2019-04-19 | Release date: | 2019-05-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med, 11, 2019
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6OML
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![BU of 6oml by Molmil](/molmil-images/mine/6oml) | Human BMP chimera BV261 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 2 and Bone morphogenetic protein 6, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Seeherman, H, Juo, Z.S. | Deposit date: | 2019-04-18 | Release date: | 2019-05-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med, 11, 2019
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2JRT
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![BU of 2jrt by Molmil](/molmil-images/mine/2jrt) | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides. Northeast Structural Genomics target RhR5 | Descriptor: | Uncharacterized protein | Authors: | Wang, L, Chen, C, Nwosu, C, Cunningham, K, Owens, L, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-28 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides. To be Published
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5TFM
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![BU of 5tfm by Molmil](/molmil-images/mine/5tfm) | Crystal Structure of Human Cadherin-23 EC6-8 | Descriptor: | CALCIUM ION, Cadherin-23, SODIUM ION | Authors: | Jaiganesh, A, Sotomayor, M. | Deposit date: | 2016-09-25 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26, 2018
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5TFK
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![BU of 5tfk by Molmil](/molmil-images/mine/5tfk) | |
5TFL
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![BU of 5tfl by Molmil](/molmil-images/mine/5tfl) | Crystal Structure of Mouse Cadherin-23 EC7+8 | Descriptor: | CALCIUM ION, Cadherin-23, SODIUM ION | Authors: | Jaiganesh, A, Sotomayor, M. | Deposit date: | 2016-09-25 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.56 Å) | Cite: | Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26, 2018
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5GNK
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![BU of 5gnk by Molmil](/molmil-images/mine/5gnk) | Crystal structure of EGFR 696-988 T790M in complex with LXX-6-34 | Descriptor: | 1,2-ETHANEDIOL, 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(1-methylimidazol-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one, CHLORIDE ION, ... | Authors: | Yan, X.E, Yun, C.H. | Deposit date: | 2016-07-21 | Release date: | 2017-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode. J. Med. Chem., 60, 2017
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5GTY
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![BU of 5gty by Molmil](/molmil-images/mine/5gty) | Crystal structure of EGFR 696-1022 T790M in complex with LXX-6-26 | Descriptor: | 1,2-ETHANEDIOL, 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(6-methylpyridin-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one, Epidermal growth factor receptor | Authors: | Yan, X.E, Yun, C.H. | Deposit date: | 2016-08-23 | Release date: | 2017-09-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode. Oncotarget, 8, 2017
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7BZV
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![BU of 7bzv by Molmil](/molmil-images/mine/7bzv) | |
2DUA
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![BU of 2dua by Molmil](/molmil-images/mine/2dua) | |
7V2Z
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![BU of 7v2z by Molmil](/molmil-images/mine/7v2z) | ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ... | Authors: | Lin, M.M, Yang, H.T. | Deposit date: | 2021-08-10 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.10101676 Å) | Cite: | Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. Acs Infect Dis., 8, 2022
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7BWQ
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![BU of 7bwq by Molmil](/molmil-images/mine/7bwq) | Structure of nonstructural protein Nsp9 from SARS-CoV-2 | Descriptor: | Nsp9, SULFATE ION | Authors: | Zhang, C, Chen, Y, Li, L, Su, D. | Deposit date: | 2020-04-15 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.954 Å) | Cite: | Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2. Mol Biomed, 1, 2020
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6W4Q
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![BU of 6w4q by Molmil](/molmil-images/mine/6w4q) | Crystal structure of full-length tailspike protein 2 (TSP2, ORF211) ) from Escherichia coli O157:H7 bacteriophage CAB120 | Descriptor: | 1,2-ETHANEDIOL, CARBONATE ION, CHLORIDE ION, ... | Authors: | Greenfield, J, Herzberg, O. | Deposit date: | 2020-03-11 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7. Sci Rep, 10, 2020
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5J39
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![BU of 5j39 by Molmil](/molmil-images/mine/5j39) | Crystal Structure of the extended TUDOR domain from TDRD2 | Descriptor: | CACODYLATE ION, Tudor and KH domain-containing protein, UNKNOWN ATOM OR ION | Authors: | Zhang, H, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2016-03-30 | Release date: | 2016-04-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3HG8
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![BU of 3hg8 by Molmil](/molmil-images/mine/3hg8) | |
8EQN
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![BU of 8eqn by Molmil](/molmil-images/mine/8eqn) | |
3IUR
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![BU of 3iur by Molmil](/molmil-images/mine/3iur) | apPEP_D266Nx+H2H3 opened state | Descriptor: | GLYCEROL, H2H3 helices from villin headpiece subdomain HP35, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Chiu, T.K. | Deposit date: | 2009-08-31 | Release date: | 2010-05-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Induced-fit mechanism for prolyl endopeptidase J.Biol.Chem., 285, 2010
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3IVM
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![BU of 3ivm by Molmil](/molmil-images/mine/3ivm) | apPEP_WT+PP closed state | Descriptor: | N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, prolyl endopeptidase | Authors: | Chiu, T.K. | Deposit date: | 2009-09-01 | Release date: | 2010-05-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Induced-fit mechanism for prolyl endopeptidase J.Biol.Chem., 285, 2010
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3IUQ
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![BU of 3iuq by Molmil](/molmil-images/mine/3iuq) | apPEP_D622N+PP closed state | Descriptor: | GLYCEROL, N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, Prolyl Endopeptidase | Authors: | Chiu, T.K. | Deposit date: | 2009-08-31 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Induced-fit mechanism for prolyl endopeptidase J.Biol.Chem., 285, 2010
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3IJK
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![BU of 3ijk by Molmil](/molmil-images/mine/3ijk) | 5-OMe modified DNA 8mer | Descriptor: | 5'-D(*GP*(UMS)P*GP*(T5O)P*AP*CP*AP*C)-3' | Authors: | Sheng, J, Zhang, W, Hassan, A.E.A, Gan, J, Huang, Z. | Deposit date: | 2009-08-04 | Release date: | 2009-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate Chemistryselect, 8, 2023
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