6OML
Human BMP chimera BV261
Summary for 6OML
Entry DOI | 10.2210/pdb6oml/pdb |
Descriptor | Bone morphogenetic protein 2 and Bone morphogenetic protein 6, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | bmp, bone morphogenetic protein, cytokine |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 24995.24 |
Authors | Seeherman, H.,Juo, Z.S. (deposition date: 2019-04-18, release date: 2019-05-15, Last modification date: 2020-07-29) |
Primary citation | Seeherman, H.J.,Berasi, S.P.,Brown, C.T.,Martinez, R.X.,Juo, Z.S.,Jelinsky, S.,Cain, M.J.,Grode, J.,Tumelty, K.E.,Bohner, M.,Grinberg, O.,Orr, N.,Shoseyov, O.,Eyckmans, J.,Chen, C.,Morales, P.R.,Wilson, C.G.,Vanderploeg, E.J.,Wozney, J.M. A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Sci Transl Med, 11:-, 2019 Cited by PubMed: 31019025DOI: 10.1126/scitranslmed.aar4953 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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