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8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ8
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BU of 8tz8 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ9
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BU of 8tz9 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ1
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BU of 8tz1 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8JLV
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BU of 8jlv by Molmil
Beneficial flip of substrate orientation enable determine substrate specificity for zearalenone lactone hydrolase
Descriptor: AB hydrolase-1 domain-containing protein
Authors:Xiang, L, Wang, M, Zhang, G, Zhou, J.
Deposit date:2023-06-02
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.998636 Å)
Cite:Enhancing the activity of zearalenone lactone hydrolase toward the more toxic alpha-zearalanol via a single-point mutation.
Appl.Environ.Microbiol., 90, 2024
5HXG
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BU of 5hxg by Molmil
STM1697-FlhD complex
Descriptor: Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697
Authors:Li, B, Yuan, Z, Qin, L, Gu, L.
Deposit date:2016-01-30
Release date:2017-02-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystal structure of STM1697-FlhD complex
To Be Published
6IBJ
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BU of 6ibj by Molmil
Copper binding protein from Laetisaria arvalis (LaX325)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity CAZyme, COPPER (II) ION
Authors:Frandsen, K.E.H, Tandrup, T, Labourel, A, Haon, M, Berrin, J.-G, Lo Leggio, L.
Deposit date:2018-11-30
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A fungal family of lytic polysaccharide monooxygenase-like copper proteins.
Nat.Chem.Biol., 16, 2020
6IBH
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BU of 6ibh by Molmil
Copper binding protein from Laetisaria arvalis (LaX325)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity CAZyme, COPPER (II) ION, ...
Authors:Frandsen, K.E.H, Tandrup, T, Labourel, A, Haon, M, Berrin, J.-G, Lo Leggio, L.
Deposit date:2018-11-30
Release date:2019-11-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A fungal family of lytic polysaccharide monooxygenase-like copper proteins.
Nat.Chem.Biol., 16, 2020
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
Descriptor: Clp amino terminal domain protein, phospho-arginine
Authors:Meinhart, A, Hoi, D.M, Clausen, T.
Deposit date:2022-10-06
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
Descriptor: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
Authors:Meinhart, A, Hoi, D.M, Clausen, T.
Deposit date:2022-10-10
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
6IZG
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BU of 6izg by Molmil
Solution structure of Ufm1 protein from Trypanosoma brucei
Descriptor: Ubiquitin-fold modifier 1
Authors:Diwu, Y, Tu, X.
Deposit date:2018-12-19
Release date:2020-01-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of TbUfm1 from Trypanosoma brucei and its binding to TbUba5.
J.Struct.Biol., 212, 2020
2FDB
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BU of 2fdb by Molmil
Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c
Descriptor: Fibroblast growth factor receptor 2, fibroblast growth factor 8 isoform B
Authors:Mohammadi, M, Olsen, S.K.
Deposit date:2005-12-13
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes Dev., 20, 2006
8CYK
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BU of 8cyk by Molmil
Crystal structure of hallucinated protein HALC1_878
Descriptor: HALC1_878
Authors:Ragotte, R.J, Bera, A.K, Milles, L.F, Wicky, B.I.M, Baker, D.
Deposit date:2022-05-23
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Robust deep learning-based protein sequence design using ProteinMPNN.
Science, 378, 2022
2HYV
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BU of 2hyv by Molmil
Human Annexin A2 with heparin hexasaccharide bound
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystallographic analysis of calcium-dependent heparin binding to annexin A2.
J.Biol.Chem., 281, 2006
5KQ5
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BU of 5kq5 by Molmil
AMPK bound to allosteric activator
Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Calabrese, M.F, Kurumbail, R.G.
Deposit date:2016-07-05
Release date:2016-08-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.
J.Med.Chem., 59, 2016
2HYU
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BU of 2hyu by Molmil
Human Annexin A2 with heparin tetrasaccharide bound
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2HYW
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BU of 2hyw by Molmil
Human Annexin A2 with Calcium bound
Descriptor: Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
8JGT
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BU of 8jgt by Molmil
Crystal structure of Deinococcus radiodurans exopolyphosphatase E114A mutant
Descriptor: Exopolyphosphatase, MAGNESIUM ION, SULFATE ION
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGQ
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BU of 8jgq by Molmil
Crystal structure of Deinococcus radiodurans exopolyphosphatase complexed with P5
Descriptor: Exopolyphosphatase, MAGNESIUM ION, SULFATE ION, ...
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGO
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BU of 8jgo by Molmil
Crystal structure of Deinococcus radiodurans exopolyphosphatase
Descriptor: Exopolyphosphatase, MAGNESIUM ION, SULFATE ION
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGW
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BU of 8jgw by Molmil
Crystal structure of Klebsiella pneumoniae exopolyphosphatase
Descriptor: Exopolyphosphatase, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024

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