4X4S
 
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4X4O
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4X4U
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3V2U
 | | Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Galactose/lactose metabolism regulatory protein GAL80, ... | | Authors: | Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. | | Deposit date: | 2011-12-12 | | Release date: | 2012-02-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.105 Å) | | Cite: | The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
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6OU9
 | | Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry | | Descriptor: | Major capsid protein | | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | Deposit date: | 2019-05-04 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OUT
 | | Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry | | Descriptor: | Capsid protein VP1 | | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | Deposit date: | 2019-05-05 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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3V5R
 | | Crystal structure of the unliganded form of Gal3p | | Descriptor: | Protein GAL3, SULFATE ION | | Authors: | Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. | | Deposit date: | 2011-12-16 | | Release date: | 2012-02-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
Genes Dev., 26, 2012
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6OUC
 | | Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry | | Descriptor: | Viral protein 1, ZINC ION | | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | Deposit date: | 2019-05-04 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OUU
 | | Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry | | Descriptor: | Major capsid protein | | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | Deposit date: | 2019-05-05 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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3TIX
 | | Crystal structure of the Chp1-Tas3 complex core | | Descriptor: | CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ... | | Authors: | Schalch, T, Joshua-Tor, L. | | Deposit date: | 2011-08-22 | | Release date: | 2011-11-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9001 Å) | | Cite: | The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS.
Nat.Struct.Mol.Biol., 18, 2011
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1R6Z
 | | The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) | | Descriptor: | Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2003-10-17 | | Release date: | 2004-01-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
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1R9W
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3BTS
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3BTU
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3BTV
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1U04
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4GGJ
 | | Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) | | Descriptor: | Mitochondrial cardiolipin hydrolase, ZINC ION | | Authors: | Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2012-08-06 | | Release date: | 2012-10-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
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4F3T
 | | Human Argonaute-2 - miR-20a complex | | Descriptor: | PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3') | | Authors: | Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L. | | Deposit date: | 2012-05-09 | | Release date: | 2012-05-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Structure of Human Argonaute-2 in Complex with miR-20a.
Cell(Cambridge,Mass.), 150, 2012
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4GGK
 | | Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate | | Descriptor: | Mitochondrial cardiolipin hydrolase, TUNGSTATE(VI)ION, ZINC ION | | Authors: | Ipsaro, J.J, Haase, A.D, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2012-08-06 | | Release date: | 2012-10-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491, 2012
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4X4V
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4X4R
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4X4W
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4X4N
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7JPO
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7JPQ
 | | ORC-O2-5: Human Origin Recognition Complex (ORC) with subunits 2,3,4,5 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 2, ... | | Authors: | Jaremko, M.J, Joshua-Tor, L. | | Deposit date: | 2020-08-09 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
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