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4GRG
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BU of 4grg by Molmil
Crystal structure of IgE complexed with E2_79, an anti-IgE inhibitor
Descriptor: ANTI-IGE INHIBITOR E2_79, Ig epsilon chain C region
Authors:Kim, B, Jardetzky, T.S.
Deposit date:2012-08-24
Release date:2012-12-12
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.24 Å)
Cite:Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.
Nature, 491, 2012
3T1E
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BU of 3t1e by Molmil
The structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a 4-helix bundle stalk
Descriptor: Hemagglutinin-neuraminidase
Authors:Yuan, P, Swanson, K, Leser, G.P, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2011-07-21
Release date:2011-09-07
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QW9
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BU of 3qw9 by Molmil
Crystal structure of betaglycan ZP-C domain
Descriptor: Transforming growth factor beta receptor type 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Lin, S.J, Jardetzky, T.S.
Deposit date:2011-02-27
Release date:2011-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-{beta} binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TSI
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BU of 3tsi by Molmil
Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain
Descriptor: Hemagglutinin-neuraminidase
Authors:Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A.
Deposit date:2011-09-13
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.
J.Virol., 85, 2011
7SHT
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BU of 7sht by Molmil
Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
Authors:Pennington, L.F, Jardetzky, T.S.
Deposit date:2021-10-11
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (7.29 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
5EJB
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BU of 5ejb by Molmil
Crystal structure of prefusion Hendra virus F protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Wong, J.W, Jardetzky, T.S, Paterson, R.G, Lamb, R.A.
Deposit date:2015-11-01
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form.
Proc.Natl.Acad.Sci.USA, 113, 2016
1NYS
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BU of 1nys by Molmil
Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1NYU
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BU of 1nyu by Molmil
Crystal Structure of Activin A Bound to the ECD of ActRIIB
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
5HYS
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BU of 5hys by Molmil
Structure of IgE complexed with omalizumab
Descriptor: Epididymis luminal protein 214, Ig epsilon chain C region, SULFATE ION, ...
Authors:Pennington, L.F, Tarchevskaya, S.S, Sathiyamoorthy, K, Jardetzky, T.S.
Deposit date:2016-02-01
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.
Nat Commun, 7, 2016
1Z4Z
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BU of 1z4z by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA(soaked with sialic acid, pH7.0))
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4W
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BU of 1z4w by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1ZTM
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BU of 1ztm by Molmil
Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein
Authors:Yin, H.S, Paterson, R.G, Wen, X, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-05-27
Release date:2005-07-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
Proc.Natl.Acad.Sci.USA, 102, 2005
1Z4X
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BU of 1z4x by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4V
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BU of 1z4v by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH 7.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z50
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BU of 1z50 by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Y
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BU of 1z4y by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
2B0U
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BU of 2b0u by Molmil
The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
1J87
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BU of 1j87 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J89
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BU of 1j89 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1KG0
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BU of 1kg0 by Molmil
Structure of the Epstein-Barr Virus gp42 Protein Bound to the MHC class II Receptor HLA-DR1
Descriptor: Hemagglutinin HA Peptide, MHC class II Receptor HLA-DR1, gp42 Protein
Authors:Mullen, M.M, Haan, K.M, Longnecker, R, Jardetzky, T.S.
Deposit date:2001-11-25
Release date:2002-03-27
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1.
Mol.Cell, 9, 2002
1J86
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BU of 1j86 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), MONOCLINIC CRYSTAL FORM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J88
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BU of 1j88 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1SVF
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BU of 1svf by Molmil
PARAMYXOVIRUS SV5 FUSION PROTEIN CORE
Descriptor: CHLORIDE ION, PROTEIN (FUSION GLYCOPROTEIN)
Authors:Baker, K.A, Dutch, R.E, Lamb, R.A, Jardetzky, T.S.
Deposit date:1999-02-27
Release date:1999-03-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for paramyxovirus-mediated membrane fusion.
Mol.Cell, 3, 1999
7MXI
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BU of 7mxi by Molmil
IgE-Fc in complex with DARPins E2_79 and E3_53
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IgE Inhibitor E2_79, DARPin E3_53, ...
Authors:Pennington, L.F, Jardetzky, T.J.
Deposit date:2021-05-19
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions.
J.Allergy Clin.Immunol., 148, 2021
5ITB
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BU of 5itb by Molmil
Crystal structure of the anti-RSV F Fab 14N4
Descriptor: anti-RSV F Fab 14N4 Heavy chain, anti-RSV F Fab 14N4 Light chain
Authors:Mousa, J.J, Crowe, J.E.
Deposit date:2016-03-16
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016

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