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4JQ2
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BU of 4jq2 by Molmil
AKR1C2 complex with sulindac
Descriptor: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, L(+)-TARTARIC ACID, ...
Authors:Yosaatmadja, Y, Flanagan, J.U, Squire, C.J.
Deposit date:2013-03-19
Release date:2014-04-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of NSAID selectivity for the aldo-keto reductase 1C family
To be Published
4JTR
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BU of 4jtr by Molmil
AKR1C2 complex with ibuprofen
Descriptor: (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, ...
Authors:Yosaatmadja, Y, Flanagan, J.U, Squire, C.J.
Deposit date:2013-03-24
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis of NSAID selectivity for the AKR1C family
To be Published
3R43
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BU of 3r43 by Molmil
AKR1C3 complexed with mefenamic acid
Descriptor: 1,2-ETHANEDIOL, 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, Aldo-keto reductase family 1 member C3, ...
Authors:Squire, C.J, Teague, R.M, Yosaatmadja, L.
Deposit date:2011-03-17
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Plos One, 7, 2012
3EE2
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BU of 3ee2 by Molmil
Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Descriptor: GLUTATHIONE, Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, ...
Authors:Oakley, A.J.
Deposit date:2008-09-04
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase
Eur.J.Med.Chem., 45, 2010
4WKQ
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BU of 4wkq by Molmil
1.85 angstrom structure of EGFR kinase domain with gefitinib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib, ...
Authors:Yosaatmadja, Y, Squire, C.J.
Deposit date:2014-10-03
Release date:2014-11-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 angstrom structure of EGFR kinase domain with gefitinib
To Be Published
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