4JQ2

AKR1C2 complex with sulindac

Summary for 4JQ2

• Entry DOI: 10.2210/pdb4jq2/pdb
• Related: 4JQ1 4JQ3 4JQ4 4JQA 4JTQ 4JTR
• Descriptor: Aldo-keto reductase family 1 member C2, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total)
• Functional Keywords: oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (Potential): P52895
• Total number of polymer chains: 2
• Total formula weight: 78113.43

Authors

Yosaatmadja, Y.,Flanagan, J.U.,Squire, C.J. (deposition date: 2013-03-19, release date: 2014-04-02, Last modification date: 2024-04-03)

• Primary citation: Yosaatmadja, Y.,Flanagan, J.U.,Squire, C.J.; Structural basis of NSAID selectivity for the aldo-keto reductase 1C family; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)