4WKQ

1.85 angstrom structure of EGFR kinase domain with gefitinib

Summary for 4WKQ

• Entry DOI: 10.2210/pdb4wkq/pdb
• Related: 2ITY
• Descriptor: Epidermal growth factor receptor, Gefitinib, SODIUM ION, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, kinase, epidermal growth factor receptor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533
• Total number of polymer chains: 1
• Total formula weight: 38244.59

Authors

Yosaatmadja, Y.,Squire, C.J. (deposition date: 2014-10-03, release date: 2014-11-05, Last modification date: 2024-03-27)

• Primary citation: Yosaatmadja, Y.,Squire, C.J.,McKeage, M.,Flanagan, J.U.; 1.85 angstrom structure of EGFR kinase domain with gefitinib; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)