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4JTR

AKR1C2 complex with ibuprofen

Summary for 4JTR
Entry DOI10.2210/pdb4jtr/pdb
Related4JQ1 4JQ2 4JQ3 4JQ4 4JQA 4JTQ
DescriptorAldo-keto reductase family 1 member C2, IBUPROFEN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total)
Functional Keywordsoxido-reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (Potential): P52895
Total number of polymer chains2
Total formula weight78231.65
Authors
Yosaatmadja, Y.,Flanagan, J.U.,Squire, C.J. (deposition date: 2013-03-24, release date: 2014-04-02, Last modification date: 2023-09-20)
Primary citationYosaatmadja, Y.,Flanagan, J.U.,Squire, C.J.
Structural basis of NSAID selectivity for the AKR1C family
To be Published,
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

229183

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