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Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from Human Acetyl-CoA Carboxylase 1
Descriptor:	Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
Authors:	Shen, Y, Tong, L.
Deposit date:	2008-03-28
Release date:	2008-05-27
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (3.21 Å)
Cite:	Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1 Biochemistry, 47, 2008

8GLU

CryoEM structure of TnsC(1-503) bound to TnsD(1-318) from E.coli Tn7
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:	Shen, Y, Guarne, A.
Deposit date:	2023-03-23
Release date:	2024-07-31
Method:	ELECTRON MICROSCOPY (3.57 Å)
Cite:	Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024

8GLW

CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:	Shen, Y, Guarne, A.
Deposit date:	2023-03-23
Release date:	2024-07-31
Method:	ELECTRON MICROSCOPY (3.51 Å)
Cite:	Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024

8GLX

CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:	Shen, Y, Guarne, A.
Deposit date:	2023-03-23
Release date:	2024-07-31
Method:	ELECTRON MICROSCOPY (3.88 Å)
Cite:	Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024

2G54

Crystal structure of Zn-bound human insulin-degrading enzyme in complex with insulin B chain
Descriptor:	1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, ZINC ION, ...
Authors:	Shen, Y, Tang, W.-J.
Deposit date:	2006-02-22
Release date:	2006-10-24
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006

2G56

crystal structure of human insulin-degrading enzyme in complex with insulin B chain
Descriptor:	1,4-DIETHYLENE DIOXIDE, Insulin, Insulin-degrading enzyme
Authors:	Shen, Y, Tang, W.-J.
Deposit date:	2006-02-22
Release date:	2006-10-24
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006

2GPW

Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor:	Biotin carboxylase
Authors:	Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:	2006-04-18
Release date:	2006-07-04
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006

2G48

crystal structure of human insulin-degrading enzyme in complex with amylin
Descriptor:	1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Islet amyloid polypeptide
Authors:	Shen, Y, Tang, W.-J.
Deposit date:	2006-02-21
Release date:	2006-10-24
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006

2G47

Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-40)
Descriptor:	1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, amyloid protein beta A4
Authors:	Shen, Y, Tang, W.-J.
Deposit date:	2006-02-21
Release date:	2006-10-24
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006

2G49

Crystal structure of human insulin-degrading enzyme in complex with glucagon
Descriptor:	1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, glucagon preproprotein
Authors:	Shen, Y, Tang, W.-J.
Deposit date:	2006-02-21
Release date:	2006-10-24
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006

7MCS

Cryo-electron microscopy structure of TnsC(1-503)A225V bound to DNA
Descriptor:	DNA (5'-D(PCPGPCPGPCPGPCPGPCPGPCPGPCPGPC)-3'), DNA (5'-D(PGPCPGPCPGPCPGPCPGPCPGPCPGPCPG)-3'), MAGNESIUM ION, ...
Authors:	Shen, Y, Ortega, J, Guarne, A.
Deposit date:	2021-04-02
Release date:	2022-02-23
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (3.56 Å)
Cite:	Structural basis for DNA targeting by the Tn7 transposon. Nat.Struct.Mol.Biol., 29, 2022

7MBW

Crystal structure of TnsC(1-503)A225V
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transposon Tn7 transposition protein TnsC
Authors:	Shen, Y, Guarne, A.
Deposit date:	2021-04-01
Release date:	2022-02-23
Last modified:	2022-03-02
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Structural basis for DNA targeting by the Tn7 transposon. Nat.Struct.Mol.Biol., 29, 2022

2GPS

Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor:	Biotin carboxylase
Authors:	Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:	2006-04-18
Release date:	2006-07-04
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006

8VCT

CyoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7 bound to ATPgS and ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, DNA (50-MER), MAGNESIUM ION, ...
Authors:	Shen, Y, Guarne, A.
Deposit date:	2023-12-14
Release date:	2024-07-31
Method:	ELECTRON MICROSCOPY (3.83 Å)
Cite:	Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024

8VCJ

CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7 bound to ATPgS and ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ...
Authors:	Shen, Y, Guarne, A.
Deposit date:	2023-12-14
Release date:	2024-07-31
Method:	ELECTRON MICROSCOPY (3.32 Å)
Cite:	Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024

4F6E

Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae
Descriptor:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MANGANESE (II) ION, ...
Authors:	Sheng, Y, Cascio, D, Valentine, J.S.
Deposit date:	2012-05-14
Release date:	2013-06-12
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae to be published

4E4E

Crystal Structure of the Y34F mutant of Saccharomyces cerevisiae Manganese Superoxide Dismutase
Descriptor:	MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
Authors:	Sheng, Y, Cascio, D, Valentine, J.S.
Deposit date:	2012-03-12
Release date:	2012-08-22
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.88 Å)
Cite:	Six-coordinate manganese(3+) in catalysis by yeast manganese superoxide dismutase. Proc.Natl.Acad.Sci.USA, 109, 2012

3LSU

Crystal Structure of SOD2 from Saccharomyces cerevisiae
Descriptor:	GLYCEROL, MANGANESE (II) ION, SODIUM ION, ...
Authors:	Sheng, Y, Cascio, D, Valentine, J.S.
Deposit date:	2010-02-12
Release date:	2011-02-23
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.896 Å)
Cite:	Crystal Structure of SOD2 from Saccharomyces cerevisiae To be Published

3QVN

Crystal Structure of cytosolic MnSOD3 from Candida albicans
Descriptor:	MANGANESE (II) ION, Manganese-containing superoxide dismutase
Authors:	Sheng, Y, Cascio, D, Valentine, J.S.
Deposit date:	2011-02-25
Release date:	2012-02-08
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Comparison of two yeast MnSODs: mitochondrial Saccharomyces cerevisiae versus cytosolic Candida albicans. J.Am.Chem.Soc., 133, 2011

2JRJ

Solution structure of the human Pirh2 RING-H2 domain. Northeast Structural Genomics Consortium Target HT2B
Descriptor:	Ring finger and CHY zinc finger domain containing protein 1, ZINC ION
Authors:	Sheng, Y, Lemak, A, Laister, R.C, Wu, B, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
Deposit date:	2007-06-27
Release date:	2007-07-10
Last modified:	2023-12-20
Method:	SOLUTION NMR
Cite:	Molecular basis of Pirh2-mediated p53 ubiquitylation. Nat.Struct.Mol.Biol., 15, 2008

4GUN

Crystal Structure of the K184R, L185P mutant manganese superoxide dismutase from Candida albicans cytosol
Descriptor:	MANGANESE (II) ION, SULFATE ION, Superoxide dismutase
Authors:	Sheng, Y, Cascio, D, Valentine, J.S.
Deposit date:	2012-08-29
Release date:	2013-09-18
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Crystal Structure of the K184R, L185P mutant manganese superoxide dismutase from Candida albicans cytosol TO BE PUBLISHED

7YV3

genetically encoded pH sensor Lime at pH10
Descriptor:	Lime
Authors:	Wen, Y, Shen, Y, Campbell, R, Lemieux, M.J.
Deposit date:	2022-08-18
Release date:	2023-08-16
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sens, 8, 2023

7YV5

genetically encoded pH sensor Lime at pH6
Descriptor:	Lime
Authors:	Wen, Y, Shen, Y, Campbell, R, Lemieux, M.J.
Deposit date:	2022-08-18
Release date:	2023-08-16
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sens, 8, 2023

3DJ3

Crystal Structure of C-terminal Truncated TIP-1 (6-113)
Descriptor:	Tax1-binding protein 3
Authors:	Shen, Y.
Deposit date:	2008-06-21
Release date:	2008-10-21
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1 J.Mol.Biol., 384, 2008

3DIW

c-terminal beta-catenin bound TIP-1 structure
Descriptor:	Tax1-binding protein 3, decameric peptide form Catenin beta-1
Authors:	Shen, Y.
Deposit date:	2008-06-21
Release date:	2008-10-21
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1 J.Mol.Biol., 384, 2008

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