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5WEU
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BU of 5weu by Molmil
Crystal Structure of H2-Dd with disulfide-linked 10mer peptide
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, Envelope glycoprotein gp160, ...
Authors:Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.584 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WET
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BU of 5wet by Molmil
Crystal Structure of H2-Dd with disulfide-linked 6mer peptide
Descriptor: Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ...
Authors:Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WER
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BU of 5wer by Molmil
Crystal Structure of TAPBPR and H2-Dd complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ...
Authors:Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (3.412 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
1DDH
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BU of 1ddh by Molmil
MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN IMMUNODOMINANT PEPTIDE P18-I10 FROM THE HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor: BETA-2 MICROGLOBULIN, HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120, MHC CLASS I H-2DD HEAVY CHAIN
Authors:Li, H, Margulies, D.H, Mariuzza, R.A.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.
J.Mol.Biol., 283, 1998
1P1Z
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BU of 1p1z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2Kb
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
Authors:Dimasi, N, Natarajan, K, Rangjin, G, Dam, J, Margulies, D.H, Mariuzza, R.A.
Deposit date:2003-04-14
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
7KGJ
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BU of 7kgj by Molmil
Crystal structure of synthetic nanobody (Sb45) complexes with SARS-CoV-2 receptor binding domain
Descriptor: Sb45, Sybody-45, Synthetic Nanobody, ...
Authors:Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2020-10-16
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7KLW
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BU of 7klw by Molmil
Crystal structure of synthetic nanobody (Sb45+Sb68) complexes with SARS-CoV-2 receptor binding domain
Descriptor: SB45, Synthetic Nanobody, SB68, ...
Authors:Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2020-11-01
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7MFV
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BU of 7mfv by Molmil
Crystal structure of synthetic nanobody (Sb16)
Descriptor: 1,2-ETHANEDIOL, Synthetic Nanobody #16 (Sb16)
Authors:Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2021-04-11
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
1FM5
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BU of 1fm5 by Molmil
CRYSTAL STRUCTURE OF HUMAN CD69
Descriptor: EARLY ACTIVATION ANTIGEN CD69
Authors:Natarajan, K, Sawicki, M.W, Margulies, D.H, Mariuzza, R.A.
Deposit date:2000-08-16
Release date:2000-12-18
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
Biochemistry, 39, 2000
7MFU
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BU of 7mfu by Molmil
Crystal structure of synthetic nanobody (Sb14+Sb68) complexes with SARS-CoV-2 receptor binding domain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Spike protein S1, ...
Authors:Jiang, J, Ahmad, J, Natarajan, K, Boyd, L.F, Margulies, D.H.
Deposit date:2021-04-11
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
5IW1
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BU of 5iw1 by Molmil
Crystal Structure of B4.2.3 T-Cell Receptor
Descriptor: T-CELL RECEPTOR ALPHA CHAIN, T-CELL RECEPTOR BETA CHAIN
Authors:Natarajan, K, Jiang, J, Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
1QO3
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BU of 1qo3 by Molmil
Complex between NK cell receptor Ly49A and its MHC class I ligand H-2Dd
Descriptor: 1,2-ETHANEDIOL, BETA-2-MICROGLOBULIN, HIV ENVELOPE GLYCOPROTEIN 120 PEPTIDE, ...
Authors:Tormo, J, Mariuzza, R.A.
Deposit date:1999-11-01
Release date:2000-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Lectin-Like Natural Killer Cell Receptor Bound to its Mhc Class I Ligand
Nature, 402, 1999
5KD7
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BU of 5kd7 by Molmil
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PV9) of HIV gp120 MN Isolate (IGPGRAFYV)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Jiang, J, Natarajan, K, Margulies, D.
Deposit date:2016-06-07
Release date:2017-10-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
5KD4
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BU of 5kd4 by Molmil
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PVI10) of HIV gp120 MN Isolate (IGPGRAFYVI)
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ...
Authors:Jiang, J, Natarajan, K, Margulies, D.
Deposit date:2016-06-07
Release date:2017-10-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
5IVX
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BU of 5ivx by Molmil
Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Natarajan, K, Jiang, J, Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
5T7G
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BU of 5t7g by Molmil
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PT9) of HIV gp120 MN Isolate (IGPGRAFYT)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Jiang, J, Natarajan, K, Margulies, D.
Deposit date:2016-09-04
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.961 Å)
Cite:Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
6B9K
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BU of 6b9k by Molmil
Solution NMR Structure of Unbound P18-I10
Descriptor: ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE
Authors:Flores-Solis, D, McShan, A, Sgourakis, N.
Deposit date:2017-10-10
Release date:2018-07-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle.
Nat. Chem. Biol., 14, 2018
5TRZ
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BU of 5trz by Molmil
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YQSGLSIVM)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Jiang, J, Natarajan, K, Margulies, D.
Deposit date:2016-10-27
Release date:2018-05-09
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Eur.J.Immunol., 2019
5TS1
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BU of 5ts1 by Molmil
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YYQSGLSIV)
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Jiang, J, Natarajan, K, Margulies, D.
Deposit date:2016-10-27
Release date:2018-05-09
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Eur.J.Immunol., 2019
1JA3
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BU of 1ja3 by Molmil
Crystal Structure of the Murine NK Cell Inhibitory Receptor Ly-49I
Descriptor: MHC class I recognition receptor Ly49I
Authors:Dimasi, N, Sawicki, W.M, Reineck, L.A, Li, Y, Natarajan, K, Murgulies, D.H, Mariuzza, A.R.
Deposit date:2001-05-29
Release date:2002-07-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family.
J.Mol.Biol., 320, 2002
7U9P
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BU of 7u9p by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NA8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ...
Authors:Tsybovsky, Y, Kwong, P.D, Farci, P.
Deposit date:2022-03-11
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
7U9O
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BU of 7u9o by Molmil
SARS-CoV-2 spike trimer RBD in complex with Fab NE12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ...
Authors:Tsybovsky, Y, Kwong, P.D, Farci, P.
Deposit date:2022-03-11
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.
Cell Rep, 41, 2022
2H1P
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BU of 2h1p by Molmil
THE THREE-DIMENSIONAL STRUCTURES OF A POLYSACCHARIDE BINDING ANTIBODY TO CRYPTOCOCCUS NEOFORMANS AND ITS COMPLEX WITH A PEPTIDE FROM A PHAGE DISPLAY LIBRARY: IMPLICATIONS FOR THE IDENTIFICATION OF PEPTIDE MIMOTOPES
Descriptor: 2H1, PA1
Authors:Young, A.C.M, Valadon, P, Casadevall, A, Scharff, M.D, Sacchettini, J.C.
Deposit date:1997-11-12
Release date:1998-01-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structures of a polysaccharide binding antibody to Cryptococcus neoformans and its complex with a peptide from a phage display library: implications for the identification of peptide mimotopes.
J.Mol.Biol., 274, 1997
7N0H
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BU of 7n0h by Molmil
CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Jiang, J, Huang, R, Margulies, D.
Deposit date:2021-05-25
Release date:2021-06-02
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021
7N0G
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BU of 7n0g by Molmil
CryoEm structure of SARS-CoV-2 spike protein (S-6P, 1-up) in complex with sybodies (Sb45)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Jiang, J, Huang, R, Margulies, D.
Deposit date:2021-05-25
Release date:2021-06-02
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction.
J.Biol.Chem., 297, 2021

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