5KD4

Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PVI10) of HIV gp120 MN Isolate (IGPGRAFYVI)

Summary for 5KD4

• Entry DOI: 10.2210/pdb5kd4/pdb
• Related: 3ECB
• Descriptor: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, Peptide of HIV gp120 MN isolate, PVI10 (IGPGRAFYVI) (3 entities in total)
• Functional Keywords: major histompatibility complex class i, mhc-i, h2-dd, h-2dd, hiv peptide, pvi10, glycoprotein, immune response, immune system
• Biological source: Mus musculus (Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01900; Secreted: P01887
• Total number of polymer chains: 6
• Total formula weight: 90301.49

Authors

Jiang, J.,Natarajan, K.,Margulies, D. (deposition date: 2016-06-07, release date: 2017-10-11, Last modification date: 2023-09-27)

• Primary citation: Frey, B.F.,Jiang, J.,Sui, Y.,Boyd, L.F.,Yu, B.,Tatsuno, G.,Billeskov, R.,Solaymani-Mohammadi, S.,Berman, P.W.,Margulies, D.H.,Berzofsky, J.A.; Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.; J. Immunol., 200:1853-1864, 2018; PubMed: 29374075; DOI: 10.4049/jimmunol.1701523

Experimental method

X-RAY DIFFRACTION (3.05 Å)