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1HIM
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BU of 1him by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
Descriptor: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-108)
Authors:Schulze-Gahmen, U, Wilson, I.A.
Deposit date:1992-07-08
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
3P3T
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BU of 3p3t by Molmil
Human transthyretin (TTR) complexed with 4-(3-(2-flourophenoxy)propyl)-3,5-dimethyl-1H-pyrazole
Descriptor: 4-[3-(2-fluorophenoxy)propyl]-3,5-dimethyl-1H-pyrazole, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2010-10-05
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
1HIL
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BU of 1hil by Molmil
STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIGEN-ANTIBODY RECOGNITION
Descriptor: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN)
Authors:Rini, J.M, Wilson, I.A.
Deposit date:1992-07-08
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
1GND
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BU of 1gnd by Molmil
GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
Descriptor: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR
Authors:Schalk, I, Zeng, K, Wu, S.-K, Stura, E.A, Metteson, J, Huang, M, Tandon, A, Wilson, I.A, Balch, W.E.
Deposit date:1996-07-10
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure and mutational analysis of Rab GDP-dissociation inhibitor.
Nature, 381, 1996
3P3R
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BU of 3p3r by Molmil
Transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone
Descriptor: (3,4-dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2010-10-05
Release date:2011-08-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
1KJV
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BU of 1kjv by Molmil
TAP-B-associated rat MHC class I molecule
Descriptor: Mature alpha chain of major histocompatibility complex class I antigen (HEAVY CHAIN), SULFATE ION, beta-2-microglobulin, ...
Authors:Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A.
Deposit date:2001-12-05
Release date:2002-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
1KPV
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BU of 1kpv by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/SEV9
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class I histocompatibility antigen, ...
Authors:Rudolph, M.G, Wilson, I.A.
Deposit date:2002-01-02
Release date:2003-06-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
1KPU
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BU of 1kpu by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/VSV8
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Wilson, I.A.
Deposit date:2002-01-02
Release date:2003-06-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
1KJM
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BU of 1kjm by Molmil
TAP-A-associated rat MHC class I molecule
Descriptor: B6 Peptide, RT1 class I histocompatibility antigen, AA alpha chain, ...
Authors:Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A.
Deposit date:2001-12-04
Release date:2002-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
7RDH
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BU of 7rdh by Molmil
Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2021-07-09
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7RTP
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BU of 7rtp by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea]
Descriptor: JTO light chain, N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea, PHOSPHATE ION
Authors:Yan, N.L, Wilson, I.A, Kelly, J.W.
Deposit date:2021-08-13
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.
Bioorg.Med.Chem.Lett., 60, 2022
7S5Q
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BU of 7s5q by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7S5R
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BU of 7s5r by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S5P
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BU of 7s5p by Molmil
Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibody CS23
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CS23 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-09-11
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Science, 375, 2022
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXJ
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BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXL
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BU of 7rxl by Molmil
Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
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BU of 7s0x by Molmil
Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-31
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0I
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BU of 7s0i by Molmil
CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2021-08-30
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.892 Å)
Cite:A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.
Mbio, 12, 2021
2KTS
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BU of 2kts by Molmil
NMR structure of the protein NP_415897.1
Descriptor: Heat shock protein hslJ
Authors:Serrano, P, Jaudzems, K, Geralt, M, Horst, R, Wuthrich, K, Wilson, I.A, Joint Center for Structural Genomics (JCSG)
Deposit date:2010-02-06
Release date:2010-02-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of the protein NP_415897.1
To be Published
2JP9
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BU of 2jp9 by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
Descriptor: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
Authors:Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2007-04-30
Release date:2007-10-30
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2O5Y
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BU of 2o5y by Molmil
Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex
Descriptor: PROGESTERONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
Authors:Verdino, P, Wilson, I.A.
Deposit date:2006-12-06
Release date:2007-12-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2NTF
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BU of 2ntf by Molmil
Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
Descriptor: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-11-07
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2K9Z
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BU of 2k9z by Molmil
NMR structure of the protein TM1112
Descriptor: uncharacterized protein TM1112
Authors:Mohanty, B, Pedrini, B, Serrano, P, Geralt, M, Horst, R, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-28
Release date:2008-11-25
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Comparison of NMR and crystal structures for the proteins TM1112 and TM1367.
Acta Crystallogr.,Sect.F, 66, 2010

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