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2OJZ
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Anti-DNA antibody ED10
Descriptor: Fab ED10 heavy chain, Fab ED10 light chain
Authors:Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
Deposit date:2007-01-15
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2O5X
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Crystal structure of 1E9 LeuH47Trp/ArgH100Trp, an engineered Diels-Alderase Fab with nM steroid-binding affinity
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, chimeric antibody Fab 1E9-DB3
Authors:Verdino, P, Wilson, I.A.
Deposit date:2006-12-06
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3J5M
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Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
2OK0
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Fab ED10-DNA complex
Descriptor: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
Authors:Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
Deposit date:2007-01-15
Release date:2007-06-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2OP4
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Crystal Structure of Quorum-Quenching Antibody 1G9
Descriptor: 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
Authors:Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A.
Deposit date:2007-01-26
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2OQJ
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Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
Descriptor: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
Authors:Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
Deposit date:2007-01-31
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
2NTF
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Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
Descriptor: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-11-07
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
3GMN
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Structure of mouse CD1d in complex with C10Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GML
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Structure of mouse CD1d in complex with C6Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
1Y18
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Fab fragment of catalytic elimination antibody 34E4 E(H50)D mutant in complex with hapten
Descriptor: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic antibody 34E4 heavy chain, ...
Authors:Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
Deposit date:2004-11-17
Release date:2005-04-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
3IMV
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Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2AFE
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Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
Descriptor: protein Asl1650
Authors:Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2005-07-25
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
1ZXT
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Crystal Structure of A Viral Chemokine
Descriptor: functional macrophage inflammatory protein 1-alpha homolog
Authors:Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A.
Deposit date:2005-06-08
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
Descriptor: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
Authors:Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2007-05-04
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2O5Y
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Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex
Descriptor: PROGESTERONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
Authors:Verdino, P, Wilson, I.A.
Deposit date:2006-12-06
Release date:2007-12-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1Y0L
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BU of 1y0l by Molmil
Catalytic elimination antibody 34E4 in complex with hapten
Descriptor: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic Antibody Fab 34E4 Heavy chain, ...
Authors:Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
Deposit date:2004-11-15
Release date:2005-04-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
2AFD
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BU of 2afd by Molmil
Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
Descriptor: protein Asl1650
Authors:Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2005-07-25
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
2AJV
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BU of 2ajv by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
Descriptor: Antibody 7A1 Fab', COCAINE
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2Q7Y
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Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Zajonc, D.M, Wilson, I.A, Teyton, L.
Deposit date:2007-06-07
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids.
J.Mol.Biol., 377, 2008
2QGE
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethylphenyl)benzoxazole
Descriptor: 2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2007-06-28
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGB
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Human transthyretin (TTR) in Apo-form
Descriptor: Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2007-06-28
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGD
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Human transthyretin (TTR) complexed with 2-(3,5-Dibromo-4-hydroxyphenyl)benzoxazole
Descriptor: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2007-06-28
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
1FGN
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MONOCLONAL MURINE ANTIBODY 5G9-ANTI-HUMAN TISSUE FACTOR
Descriptor: IMMUNOGLOBULIN FAB 5G9
Authors:Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A.
Deposit date:1997-04-10
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
1FIG
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BU of 1fig by Molmil
ROUTES TO CATALYSIS: STRUCTURE OF A CATALYTIC ANTIBODY AND COMPARISON WITH ITS NATURAL COUNTERPART
Descriptor: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, IGG1-KAPPA 1F7 FAB (HEAVY CHAIN), IGG1-KAPPA 1F7 FAB (LIGHT CHAIN)
Authors:Haynes, M.R, Stura, E.A, Hilvert, D, Wilson, I.A.
Deposit date:1994-01-07
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart.
Science, 263, 1994
1FZM
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MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:2000-10-03
Release date:2001-03-28
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001

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