2Z2A
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![BU of 2z2a by Molmil](/molmil-images/mine/2z2a) | Thr109Gly dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
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4CLM
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![BU of 4clm by Molmil](/molmil-images/mine/4clm) | Structure of Salmonella typhi type I dehydroquinase irreversibly inhibited with a 1,3,4-trihydroxyciclohexane-1-carboxylic acid derivative | Descriptor: | (1~{S},3~{S},4~{R},5~{R})-3-methyl-1,4,5-tris(hydroxyl)cyclohexane-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, ... | Authors: | Otero, J.M, Llamas-Saiz, A.L, Tizon, L, Maneiro, M, Lence, E, Poza, S, Lamb, H, Hawkins, A.R, Blanco, B, Sedes, A, Peon, A, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2014-01-15 | Release date: | 2014-11-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Irreversible covalent modification of type I dehydroquinase with a stable Schiff base. Org. Biomol. Chem., 13, 2015
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2AAN
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3CT2
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![BU of 3ct2 by Molmil](/molmil-images/mine/3ct2) | Crystal structure of muconate cycloisomerase from Pseudomonas fluorescens | Descriptor: | MAGNESIUM ION, Muconate cycloisomerase | Authors: | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-04-11 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes. Biochemistry, 48, 2009
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1ZAV
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![BU of 1zav by Molmil](/molmil-images/mine/1zav) | Ribosomal Protein L10-L12(NTD) Complex, Space Group P21 | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L7/L12 | Authors: | Diaconu, M, Kothe, U, Schluenzen, F, Fischer, N, Harms, J.M, Tonevitski, A.G, Stark, H, Rodnina, M.V, Wahl, M.C. | Deposit date: | 2005-04-07 | Release date: | 2005-07-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation. Cell(Cambridge,Mass.), 121, 2005
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1Z7F
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4BMK
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![BU of 4bmk by Molmil](/molmil-images/mine/4bmk) | Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine | Descriptor: | Decarboxylated Myriocin, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wadsworth, J.M, Clarke, D.J, McMahon, S.A, Beattie, A.E, Lowther, J, Dunn, T.M, Naismith, J.H, Campopiano, D.J. | Deposit date: | 2013-05-09 | Release date: | 2013-09-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin. J.Am.Chem.Soc., 135, 2013
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3CF2
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![BU of 3cf2 by Molmil](/molmil-images/mine/3cf2) | Structure of P97/vcp in complex with ADP/AMP-PNP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | Deposit date: | 2008-03-01 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure, 16, 2008
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4BWY
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![BU of 4bwy by Molmil](/molmil-images/mine/4bwy) | P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32) | Descriptor: | P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-07-05 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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4C04
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![BU of 4c04 by Molmil](/molmil-images/mine/4c04) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with inhibitor | Descriptor: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN | Authors: | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | Deposit date: | 2013-07-31 | Release date: | 2014-07-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.576 Å) | Cite: | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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1YYM
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![BU of 1yym by Molmil](/molmil-images/mine/1yym) | crystal structure of F23, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), ... | Authors: | Huang, C.C, Stricher, F, Martin, L, Decker, J.M, Majeed, S, Barthe, P, Hendrickson, W.A, Robinson, J, Roumestand, C, Sodroski, J, Wyatt, R, Shaw, G.M, Vita, C, Kwong, P.D. | Deposit date: | 2005-02-25 | Release date: | 2005-05-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure, 13, 2005
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4EP6
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![BU of 4ep6 by Molmil](/molmil-images/mine/4ep6) | Crystal structure of the XplA heme domain in complex with imidazole and PEG | Descriptor: | Cytochrome P450-like protein XplA, IMIDAZOLE, PENTAETHYLENE GLYCOL, ... | Authors: | Bui, S.H, McLean, K.J, Cheesman, M.R, Bradley, J.M, Rigby, S.E.J, Leys, D, Munro, A.W. | Deposit date: | 2012-04-17 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Unusual Spectroscopic and Ligand Binding Properties of the Cytochrome P450-Flavodoxin Fusion Enzyme XplA. J.Biol.Chem., 287, 2012
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1Z5C
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![BU of 1z5c by Molmil](/molmil-images/mine/1z5c) | Topoisomerase VI-B, ADP Pi bound dimer form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Corbett, K.D, Berger, J.M. | Deposit date: | 2005-03-17 | Release date: | 2005-06-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI. Structure, 13, 2005
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1Z71
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![BU of 1z71 by Molmil](/molmil-images/mine/1z71) | thrombin and P2 pyridine N-oxide inhibitor complex structure | Descriptor: | Hirudin IIIB', L17, thrombin | Authors: | Nantermet, P.G, Burgey, C.S, Robinson, K.A, Pellicore, J.M, Newton, C.L, Deng, J.Z, Lyle, T.A, Selnick, H.G, Lewis, S.D, Lucas, B.J, Krueger, J.A, Miller-Stein, C, White, R.B, Wong, B, McMasters, D.R, Wallace, A.A, Lynch Jr, J.J, Yan, Y, Chen, Z, Kuo, L, Gardell, S.J, Shafer, J.A, Vacca, J.P. | Deposit date: | 2005-03-23 | Release date: | 2005-05-17 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | P(2) pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold BIOORG.MED.CHEM.LETT., 15, 2005
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1Z79
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1ZXQ
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![BU of 1zxq by Molmil](/molmil-images/mine/1zxq) | THE CRYSTAL STRUCTURE OF ICAM-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, INTERCELLULAR ADHESION MOLECULE-2 | Authors: | Casasnovas, J.M, Springer, T.A, Harrison, S.C, Wang, J.-H. | Deposit date: | 1997-03-04 | Release date: | 1997-09-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. Nature, 387, 1997
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1ZZY
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![BU of 1zzy by Molmil](/molmil-images/mine/1zzy) | |
4FOF
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![BU of 4fof by Molmil](/molmil-images/mine/4fof) | Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain | Descriptor: | Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form, ... | Authors: | Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D. | Deposit date: | 2012-06-20 | Release date: | 2013-01-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.416 Å) | Cite: | A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes. Structure, 21, 2013
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3CMG
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![BU of 3cmg by Molmil](/molmil-images/mine/3cmg) | Crystal structure of putative beta-galactosidase from Bacteroides fragilis | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Ramagopal, U.A, Rutter, M, Toro, R, Hu, S, Maletic, M, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-03-21 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of putative beta-galactosidase from Bacteroides fragilis. To be published
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3COK
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![BU of 3cok by Molmil](/molmil-images/mine/3cok) | Crystal structure of PLK4 kinase | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, Serine/threonine-protein kinase PLK4 | Authors: | Atwell, S, Burley, S.K, Houle, A, Leon, B, Pelletier, L.A, Sauder, J.M, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-03-28 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of PLK4 kinase. To be Published
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2A11
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![BU of 2a11 by Molmil](/molmil-images/mine/2a11) | |
4FM9
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![BU of 4fm9 by Molmil](/molmil-images/mine/4fm9) | Human topoisomerase II alpha bound to DNA | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ... | Authors: | Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M. | Deposit date: | 2012-06-15 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage. J.Mol.Biol., 424, 2012
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3CTD
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![BU of 3ctd by Molmil](/molmil-images/mine/3ctd) | Crystal structure of a putative AAA family ATPase from Prochlorococcus marinus subsp. pastoris | Descriptor: | Putative ATPase, AAA family | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Lau, C, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-04-11 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a putative AAA family ATPase from Prochlorococcus marinus subsp. pastoris. To be Published
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3CKX
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![BU of 3ckx by Molmil](/molmil-images/mine/3ckx) | Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine | Descriptor: | STAUROSPORINE, Serine/threonine-protein kinase 24 | Authors: | Antonysamy, S.S, Burley, S.K, Buchanan, S, Chau, F, Feil, I, Wu, L, Sauder, J.M, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-03-17 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine. To be Published
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2A66
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![BU of 2a66 by Molmil](/molmil-images/mine/2a66) | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter | Descriptor: | 5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3', 5'-D(*GP*TP*TP*CP*AP*AP*GP*GP*CP*CP*AP*G)-3', ACETATE ION, ... | Authors: | Solomon, I.H, Hager, J.M, Safi, R, McDonnell, D.P, Redinbo, M.R, Ortlund, E.A. | Deposit date: | 2005-07-01 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Human LRH-1 DBD-DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity. J.Mol.Biol., 354, 2005
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