4BMK
Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine
Summary for 4BMK
Entry DOI | 10.2210/pdb4bmk/pdb |
Descriptor | SERINE PALMITOYLTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, Decarboxylated Myriocin, ... (5 entities in total) |
Functional Keywords | transferase-antibiotic complex, transferase, external aldimine, inhibitor, sphingolipids, natural product, antibiotic isp-1, transferase/antibiotic |
Biological source | SPHINGOMONAS PAUCIMOBILIS |
Total number of polymer chains | 2 |
Total formula weight | 96081.49 |
Authors | Wadsworth, J.M.,Clarke, D.J.,McMahon, S.A.,Beattie, A.E.,Lowther, J.,Dunn, T.M.,Naismith, J.H.,Campopiano, D.J. (deposition date: 2013-05-09, release date: 2013-09-04, Last modification date: 2023-12-20) |
Primary citation | Wadsworth, J.M.,Clarke, D.J.,Mcmahon, S.A.,Lowther, J.P.,Beattie, A.E.,Langridge-Smith, P.R.R.,Broughton, H.B.,Dunn, T.M.,Naismith, J.H.,Campopiano, D.J. The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin. J.Am.Chem.Soc., 135:14276-, 2013 Cited by PubMed: 23957439DOI: 10.1021/JA4059876 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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