4CLM

Structure of Salmonella typhi type I dehydroquinase irreversibly inhibited with a 1,3,4-trihydroxyciclohexane-1-carboxylic acid derivative

Summary for 4CLM

Entry DOI	10.2210/pdb4clm/pdb
Related	4CKW 4CKX 4CKY 4CKZ 4CL0
Descriptor	3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, LITHIUM ION, ... (5 entities in total)
Functional Keywords	type i dehydroquinase, lyase, inhibitor, shikimis acid pathway, substrate specificity
Biological source	SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI
Total number of polymer chains	2
Total formula weight	55665.48
Authors	Otero, J.M.,Llamas-Saiz, A.L.,Tizon, L.,Maneiro, M.,Lence, E.,Poza, S.,Lamb, H.,Hawkins, A.R.,Blanco, B.,Sedes, A.,Peon, A.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-15, release date: 2014-11-05, Last modification date: 2023-12-20)
Primary citation	Tizon, L.,Maneiro, M.,Peon, A.,Otero, J.M.,Lence, E.,Poza, S.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Irreversible covalent modification of type I dehydroquinase with a stable Schiff base. Org. Biomol. Chem., 13:706-716, 2015 Cited by PubMed: 25370445 DOI: 10.1039/c4ob01782j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation