4CKX
Structure of the Mycobacterium tuberculosis Type II Dehydroquinase N12S mutant (Crystal Form 2)
Summary for 4CKX
Entry DOI | 10.2210/pdb4ckx/pdb |
Related | 4CKW 4CKY 4CKZ 4CL0 |
Descriptor | 3-DEHYDROQUINATE DEHYDRATASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
Functional Keywords | bacterial proteins, binding sites, type 2 dehydroquinase, lyase, inhibitor, protein binding, shikimis acid pathway, substrate specificity |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 1 |
Total formula weight | 15771.85 |
Authors | Otero, J.M.,Llamas-Saiz, A.L.,Maneiro, M.,Peon, A.,Sedes, A.,Lamb, H.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-10, release date: 2015-03-25, Last modification date: 2023-12-20) |
Primary citation | Maneiro, M.,Otero, J.M.,Peon, A.,Sedes, A.,Llamas-Saiz, A.L.,Lamb, H.,Hawkins, A.R.,van Raaij, M.J.,Gonzalez-Bello, C. Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase To be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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