4CKX

Structure of the Mycobacterium tuberculosis Type II Dehydroquinase N12S mutant (Crystal Form 2)

Summary for 4CKX

• Entry DOI: 10.2210/pdb4ckx/pdb
• Related: 4CKW 4CKY 4CKZ 4CL0
• Descriptor: 3-DEHYDROQUINATE DEHYDRATASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: bacterial proteins, binding sites, type 2 dehydroquinase, lyase, inhibitor, protein binding, shikimis acid pathway, substrate specificity
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 15771.85

Authors

Otero, J.M.,Llamas-Saiz, A.L.,Maneiro, M.,Peon, A.,Sedes, A.,Lamb, H.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-10, release date: 2015-03-25, Last modification date: 2023-12-20)

• Primary citation: Maneiro, M.,Otero, J.M.,Peon, A.,Sedes, A.,Llamas-Saiz, A.L.,Lamb, H.,Hawkins, A.R.,van Raaij, M.J.,Gonzalez-Bello, C.; Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)