8XAX
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8XAW
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8XAU
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![BU of 8xau by Molmil](/molmil-images/mine/8xau) | Cryo-EM structure of HerA | Descriptor: | ATP-binding protein | Authors: | Wang, Y, Deng, Z. | Deposit date: | 2023-12-05 | Release date: | 2024-06-05 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 34, 2024
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8XAY
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3UYS
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![BU of 3uys by Molmil](/molmil-images/mine/3uys) | Crystal structure of apo human ck1d | Descriptor: | Casein kinase I isoform delta, SULFATE ION | Authors: | Huang, X. | Deposit date: | 2011-12-06 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor. J.Med.Chem., 55, 2012
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8XAV
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![BU of 8xav by Molmil](/molmil-images/mine/8xav) | Cryo-EM structure of an anti-phage defense complex | Descriptor: | ATP-binding protein, DUF4297 | Authors: | Wang, Y, Deng, Z. | Deposit date: | 2023-12-05 | Release date: | 2024-06-05 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 34, 2024
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3UYT
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![BU of 3uyt by Molmil](/molmil-images/mine/3uyt) | crystal structure of ck1d with PF670462 from P1 crystal form | Descriptor: | 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine, Casein kinase I isoform delta, SULFATE ION | Authors: | Huang, X. | Deposit date: | 2011-12-06 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor. J.Med.Chem., 55, 2012
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7JUO
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![BU of 7juo by Molmil](/molmil-images/mine/7juo) | CBP bromodomain complexed with YF2-23 | Descriptor: | CREB-binding protein, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide | Authors: | Ratia, K.M, Xiong, R, Principe, D, Li, Y, Huang, F, Rana, A, Thatcher, G. | Deposit date: | 2020-08-20 | Release date: | 2021-09-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proc.Natl.Acad.Sci.USA, 119, 2022
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3UNM
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![BU of 3unm by Molmil](/molmil-images/mine/3unm) | Crystal Structure of The Human MDC1 FHA Domain | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Luo, S, Ye, K. | Deposit date: | 2011-11-16 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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3UZP
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![BU of 3uzp by Molmil](/molmil-images/mine/3uzp) | crystal structure of ck1d with PF670462 from P21 crystal form | Descriptor: | 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine, Casein kinase I isoform delta | Authors: | Huang, X. | Deposit date: | 2011-12-07 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor. J.Med.Chem., 55, 2012
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3UNN
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2FTK
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![BU of 2ftk by Molmil](/molmil-images/mine/2ftk) | berylloflouride Spo0F complex with Spo0B | Descriptor: | MAGNESIUM ION, Sporulation initiation phosphotransferase B, Sporulation initiation phosphotransferase F | Authors: | Varughese, K.I. | Deposit date: | 2006-01-24 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | The Crystal Structure of Beryllofluoride Spo0F in Complex with the Phosphotransferase Spo0B Represents a Phosphotransfer Pretransition State. J.Bacteriol., 188, 2006
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8TNL
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1BLS
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6CFI
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![BU of 6cfi by Molmil](/molmil-images/mine/6cfi) | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... | Authors: | Min, J, Jeffrey, P.D. | Deposit date: | 2018-02-15 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.36241913 Å) | Cite: | Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex. Nucleic Acids Res., 47, 2019
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8G92
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![BU of 8g92 by Molmil](/molmil-images/mine/8g92) | Structure of inhibitor 16d-bound SPNS2 | Descriptor: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, Sphingosine-1-phosphate transporter SPNS2 | Authors: | Chen, H, Li, X. | Deposit date: | 2023-02-21 | Release date: | 2023-05-24 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. Cell, 186, 2023
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8XK6
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![BU of 8xk6 by Molmil](/molmil-images/mine/8xk6) | S2A5 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. To Be Published
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8XKF
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![BU of 8xkf by Molmil](/molmil-images/mine/8xkf) | Crystal structure of Helicobacter pylori IspDF with substrate CTP | Descriptor: | 1,2-ETHANEDIOL, Bifunctional enzyme IspD/IspF, CHLORIDE ION, ... | Authors: | Chen, X, Wu, D. | Deposit date: | 2023-12-23 | Release date: | 2024-04-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes. Int J Antimicrob Agents, 63, 2024
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8XKG
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![BU of 8xkg by Molmil](/molmil-images/mine/8xkg) | Crystal structure of Acinetobacter baumannii IspD | Descriptor: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, GLYCEROL | Authors: | Chen, X, Wu, D. | Deposit date: | 2023-12-23 | Release date: | 2024-04-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes. Int J Antimicrob Agents, 63, 2024
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8XHU
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![BU of 8xhu by Molmil](/molmil-images/mine/8xhu) | Crystal structure of Helicobacter pylori IspDF | Descriptor: | 1,2-ETHANEDIOL, Bifunctional enzyme IspD/IspF, CHLORIDE ION, ... | Authors: | Chen, X, Wu, D. | Deposit date: | 2023-12-18 | Release date: | 2024-04-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes. Int J Antimicrob Agents, 63, 2024
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8XK5
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![BU of 8xk5 by Molmil](/molmil-images/mine/8xk5) | SNB1G11 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. To Be Published
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6IYX
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![BU of 6iyx by Molmil](/molmil-images/mine/6iyx) | Crystal Structure Analysis of a Eukaryotic Membrane Protein | Descriptor: | BROMIDE ION, CALCIUM ION, Trimeric intracellular cation channel type A | Authors: | Zeng, Y, Wang, X.H, Gao, F, Su, M, Chen, Y.H. | Deposit date: | 2018-12-17 | Release date: | 2019-05-01 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IZ5
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6IZ6
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![BU of 6iz6 by Molmil](/molmil-images/mine/6iz6) | Crystal Structure Analysis of TRIC counter-ion channels in calcium release | Descriptor: | CALCIUM ION, Trimeric intracellular cation channel type B-B | Authors: | Liu, X.L, Wang, X.H, Su, M, Hendrickson, W.A, Chen, Y.H. | Deposit date: | 2018-12-18 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.293 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IZF
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![BU of 6izf by Molmil](/molmil-images/mine/6izf) | Structural basis for activity of TRIC counter-ion channels in calcium release | Descriptor: | (2R)-1-(dodecanoyloxy)-3-hydroxypropan-2-yl (5E,8E,11E)-tetradeca-5,8,11-trienoate, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wang, X.H, Zeng, Y, Su, M, Hendrickson, W.A, Chen, Y.H. | Deposit date: | 2018-12-19 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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