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2XQ2
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Structure of the K294A mutant of vSGLT
分子名称: DI(HYDROXYETHYL)ETHER, SODIUM/GLUCOSE COTRANSPORTER
著者Watanabe, A, Choe, S, Chaptal, V, Rosenberg, J.M, Wright, E.M, Grabe, M, Abramson, J.
登録日2010-09-01
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献The Mechanism of Sodium and Substrate Release from the Binding Pocket of Vsglt
Nature, 468, 2010
1L6G
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Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine
分子名称: N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase
著者Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N.
登録日2002-03-10
公開日2002-06-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
1L6F
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Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine
分子名称: ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase
著者Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N.
登録日2002-03-09
公開日2002-06-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
8HG6
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BU of 8hg6 by Molmil
Cryo-EM structure of the prasinophyte-specific light-harvesting complex (Lhcp)from Ostreococcus tauri
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ...
著者Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z.
登録日2022-11-13
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers.
Elife, 12, 2023
8HG5
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Cryo-EM structure of the prasinophyte-specific light-harvesting complex (Lhcp)from Ostreococcus tauri
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ...
著者Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z.
登録日2022-11-13
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers.
Elife, 12, 2023
8HG3
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Cryo-EM structure of the Lhcp complex from Ostreococcus tauri
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ...
著者Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z.
登録日2022-11-13
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers.
Elife, 12, 2023
6KAD
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Cryo-EM structure of the C2S2M2L2-type PSII-LHCII supercomplex from Chlamydomonas reihardtii
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
著者Sheng, X, Watanabe, A, Li, A.J, Kim, E, Song, C, Murata, K, Song, D.F, Minagawa, J, Liu, Z.F.
登録日2019-06-21
公開日2019-10-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insight into light harvesting for photosystem II in green algae.
Nat.Plants, 5, 2019
6KJO
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BU of 6kjo by Molmil
The microtubule-binding domains of yeast cytoplasmic dynein in the low affinity state
分子名称: Dynein heavy chain, cytoplasmic
著者Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M.
登録日2019-07-22
公開日2020-03-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
6KJN
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The microtubule-binding domains of yeast cytoplasmic dynein in the high affinity state
分子名称: Dynein heavy chain, cytoplasmic
著者Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M.
登録日2019-07-22
公開日2020-03-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
3WVZ
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BU of 3wvz by Molmil
Crystal structure of Hikeshi, a new nuclear transport receptor of Hsp70
分子名称: Protein Hikeshi
著者Song, J, Kose, S, Watanabe, A, Son, S.Y, Choi, S, Hong, R.H, Yamashita, E, Park, I.Y, Imamoto, N, Lee, S.J.
登録日2014-06-12
公開日2015-03-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
3WW0
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Crystal structure of F97A mutant, a new nuclear transport receptor of Hsp70
分子名称: Protein Hikeshi
著者Song, J, Kose, S, Watanabe, A, Son, S.Y, Choi, S, Hong, R.H, Yamashita, E, Park, I.Y, Imamoto, N, Lee, S.J.
登録日2014-06-12
公開日2015-03-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
7YCA
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BU of 7yca by Molmil
Cryo-EM structure of the PSI-LHCI-Lhcp supercomplex from Ostreococcus tauri
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
著者Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z.
登録日2022-07-01
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers.
Elife, 12, 2023
7YF6
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Crystal structure of HIV-1 protease in complex with macrocyclic peptide
分子名称: MAGNESIUM ION, Macrocyclic Peptide, Protease
著者Kusumoto, Y, Sato, S, Yamada, T, Kozono, I, Nakata, Z, Asada, N, Mitsuki, S, Wakasa-Morimoto, C, Tohru, M, Watanabe, A, Hayashi, K, Mikamiyama, H.
登録日2022-07-07
公開日2022-11-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization.
Acs Med.Chem.Lett., 13, 2022
6E4X
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BU of 6e4x by Molmil
Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2018-07-18
公開日2019-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177, 2019
6E56
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Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2018-07-19
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177, 2019
5W0D
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BU of 5w0d by Molmil
Inferred precursor (UCA) of the human antibody lineage K03.12 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2017-05-30
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
8UDG
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BU of 8udg by Molmil
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
分子名称: Hemagglutinin, S1V2-72 heavy chain, S1V2-72 light chain
著者Finney, J, Kong, S, Walsh Jr, R.M, Harrison, S.C, Kelsoe, G.
登録日2023-09-28
公開日2023-11-15
最終更新日2024-01-10
実験手法ELECTRON MICROSCOPY (4.98 Å)
主引用文献Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 121, 2024
7EBT
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Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in glutathione-bound form
分子名称: CALCIUM ION, GLUTATHIONE, Glutathione transferase
著者Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R.
登録日2021-03-11
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
7EBW
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Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in desmethylglycitein and glutathione-bound form
分子名称: 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ...
著者Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R.
登録日2021-03-11
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
7EBV
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Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in luteolin- and glutathione-bound form
分子名称: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ...
著者Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R.
登録日2021-03-11
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
7EBU
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Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in Daidzein- and glutathione-bound form
分子名称: 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ...
著者Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R.
登録日2021-03-11
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
7TRH
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Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181)
分子名称: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain
著者McCarthy, K.R.
登録日2022-01-28
公開日2023-08-02
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
Plos Biol., 21, 2023
7TRI
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Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2)
分子名称: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ...
著者McCarthy, K.R.
登録日2022-01-28
公開日2023-08-02
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
Plos Biol., 21, 2023
5ZA1
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Ligand complex of RORgt LBD
分子名称: 1,2-ETHANEDIOL, 2-[4-({[4-(ethylsulfonyl)phenyl]acetyl}amino)phenyl]-2-methyl-N-phenylpropanamide, DIMETHYLFORMAMIDE, ...
著者Yamamoto, S, Yamaguchi, H.
登録日2018-02-06
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (ROR gamma t) inhibitor, S18-000003.
Bioorg. Med. Chem. Lett., 28, 2018
5W08
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A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2017-05-30
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018

 

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