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8HIB
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BU of 8hib by Molmil
The crystal structure of Pygo2-LDB1-SSBP2 triple complex
分子名称: LIM domain-binding protein 1, Pygopus homolog 2, Single-stranded DNA-binding protein 2
著者Wang, H.Y, Yan, X.X, Xu, W.Q.
登録日2022-11-19
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The crystal structure of Pygo2-LDB1-SSBP2 triple complex
To Be Published
6JPD
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BU of 6jpd by Molmil
Mouse receptor-interacting protein kinase 3 (RIP3) amyloid structure by solid-state NMR
分子名称: Receptor-interacting serine/threonine-protein kinase 3
著者Wu, X.L, Hu, H, Zhang, J, Dong, X.Q, Wang, J, Schwieters, C, Wang, H.Y, Lu, J.X.
登録日2019-03-26
公開日2020-10-28
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis.
Nat Commun, 12, 2021
1L1J
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BU of 1l1j by Molmil
Crystal structure of the protease domain of an ATP-independent heat shock protease HtrA
分子名称: heat shock protease HtrA
著者Kim, D.Y, Kim, D.R, Ha, S.C, Lokanath, N.K, Hwang, H.Y, Kim, K.K.
登録日2002-02-18
公開日2003-04-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Protease Domain of a Heat-shock Protein HtrA from Thermotoga maritima
J.BIOL.CHEM., 278, 2003
1YGZ
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BU of 1ygz by Molmil
Crystal Structure of Inorganic Pyrophosphatase from Helicobacter pylori
分子名称: Inorganic pyrophosphatase
著者Wu, C.A, Lokanath, N.K, Kim, D.Y, Park, H.J, Hwang, H.Y, Kim, S.T, Suh, S.W, Kim, K.K.
登録日2005-01-06
公開日2005-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of inorganic pyrophosphatase from Helicobacter pylori.
Acta Crystallogr.,Sect.D, 61, 2005
3QBQ
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BU of 3qbq by Molmil
Crystal structure of extracellular domains of mouse RANK-RANKL complex
分子名称: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A
著者Ta, H.M, Nguyen, G.T.T, Jin, H.M, Choi, J.K, Park, H, Kim, N.S, Hwang, H.Y, Kim, K.K.
登録日2011-01-13
公開日2011-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
Proc.Natl.Acad.Sci.USA, 107, 2010
4LFU
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BU of 4lfu by Molmil
Crystal structure of Escherichia coli SdiA in the space group C2
分子名称: CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-27
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4LGW
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BU of 4lgw by Molmil
Crystal structure of Escherichia coli SdiA in the space group P6522
分子名称: GLYCEROL, Regulatory protein SdiA
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-28
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4YGQ
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BU of 4ygq by Molmil
Crystal structure of HAD phosphatase from Thermococcus onnurineus
分子名称: Hydrolase, TERTIARY-BUTYL ALCOHOL
著者Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y.
登録日2015-02-26
公開日2015-04-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1
Biochem.Biophys.Res.Commun., 461, 2015
4YGR
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BU of 4ygr by Molmil
Crystal structure of HAD phosphatase from Thermococcus onnurineus
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hydrolase, MAGNESIUM ION
著者Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y.
登録日2015-02-26
公開日2015-04-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1
Biochem.Biophys.Res.Commun., 461, 2015
4YGS
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BU of 4ygs by Molmil
Crystal structure of HAD phosphatase from Thermococcus onnurineus
分子名称: CITRIC ACID, Hydrolase, MAGNESIUM ION
著者Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y.
登録日2015-02-26
公開日2015-04-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1
Biochem.Biophys.Res.Commun., 461, 2015
6IWV
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BU of 6iwv by Molmil
Crystal structure of a single strand DNA binding protein
分子名称: Single-stranded DNA-binding protein 2
著者Wang, H.Y, Yan, X.X.
登録日2018-12-07
公開日2019-08-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure of the LUFS domain of human single-stranded DNA binding Protein 2 (SSBP2).
Protein Sci., 28, 2019
6JBZ
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BU of 6jbz by Molmil
Structural analysis of molybdopterin synthases from two mycobacteria pathogens
分子名称: MoaD/ThiS family protein, Molybdenum cofactor biosynthesis protein E, SULFATE ION
著者Wang, H.Y, Liu, X.
登録日2019-01-27
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structural analysis of molybdopterin synthases from two mycobacterial pathogens.
Biochem. Biophys. Res. Commun., 511, 2019
8K3K
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BU of 8k3k by Molmil
The crystal structure of nanobody Nb4 in complex with receptor binding domain (RBD) of BA.1 Spike protein
分子名称: Nanobody Nb4, Spike protein S1
著者Wang, H.Y, Xu, W.Q.
登録日2023-07-16
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
6LK5
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BU of 6lk5 by Molmil
MLKL mutant - T357ES358D
分子名称: Mixed lineage kinase domain-like protein
著者Wang, H.Y, Li, S, Zhang, Y.
登録日2019-12-18
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.
Cell Death Dis, 12, 2021
5Y0G
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BU of 5y0g by Molmil
Crystal structure of human FABP4 complexed with ligand 4-Fluoro-3-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid
分子名称: 4-fluoranyl-3-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-17
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.542 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y0X
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BU of 5y0x by Molmil
Crystal structure of human FABP4 complexed with ligand 2-fluoro-3-((4-methoxynaphthalene)-1-sulfonamido)benzoic acid
分子名称: 2-fluoranyl-3-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y13
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BU of 5y13 by Molmil
Crystal structure of human FABP4 complexed with ligand 5-((4-bromonaphthalene)-1-sulfonamido)pentanoic acid
分子名称: 5-[(4-bromanylnaphthalen-1-yl)sulfonylamino]pentanoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y0F
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BU of 5y0f by Molmil
Crystal structure of human FABP4 complexed with ligand 2-fluoro-5-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid
分子名称: 2-fluoranyl-5-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-17
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y12
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BU of 5y12 by Molmil
Crystal structure of human FABP4 complexed with ligand 5-((4-methoxynaphthalene)-1-sulfonamido)pentanoic acid
分子名称: 5-[(4-methoxynaphthalen-1-yl)sulfonylamino]pentanoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
3F21
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BU of 3f21 by Molmil
Crystal structure of Zalpha in complex with d(CACGTG)
分子名称: DNA (5'-D(*DTP*DCP*DAP*DCP*DGP*DTP*DG)-3'), Double-stranded RNA-specific adenosine deaminase
著者Ha, S.C, Choi, J, Kim, K.K.
登録日2008-10-28
公開日2008-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Nucleic Acids Res., 37, 2009
8G61
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BU of 8g61 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
著者Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
登録日2023-02-14
公開日2023-04-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8GLP
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BU of 8glp by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C.
登録日2023-03-22
公開日2023-04-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.67 Å)
主引用文献mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
著者Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
登録日2023-02-14
公開日2023-04-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
分子名称: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
著者Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
登録日2023-02-15
公開日2023-04-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Y
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BU of 8g5y by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
著者Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
登録日2023-02-14
公開日2023-04-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.29 Å)
主引用文献mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023

 

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