8ESI
 
 | | Bile Salt Hydrolase from B. longum with covalent inhibitor bound | | 分子名称: | (1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-1-[(2R)-6-fluoro-5-oxohexan-2-yl]-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl hydrogen sulfate (non-preferred name), Conjugated bile acid hydrolase | | 著者 | Walker, M.E, Lim, L, Redinbo, M.R. | | 登録日 | 2022-10-14 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8ETF
 | | Bile Salt Hydrolase B from Lactobacillus gasseri with covalent inhibitor bound | | 分子名称: | (5R)-1-fluoro-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]hexan-2-one (non-preferred name), Choloylglycine hydrolase, NICKEL (II) ION | | 著者 | Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-10-17 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8ESG
 | | Bile Salt Hydrolase B from Lactobacillus gasseri with covalent inhibitor bound | | 分子名称: | (1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-1-[(2R)-6-fluoro-5-oxohexan-2-yl]-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl hydrogen sulfate (non-preferred name), Choloylglycine hydrolase | | 著者 | Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-10-14 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8ETK
 | | Bile salt hydrolase A from Lactobacillus gasseri bound to covalent probe | | 分子名称: | (5R)-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-9a,11a-dimethyl-7-(2-{2-[(prop-2-yn-1-yl)oxy]ethoxy}ethoxy)hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-1-fluorohexan-2-one (non-preferred name), Conjugated bile salt hydrolase, SODIUM ION | | 著者 | Walker, M.E, Grundy, M.K, Redinbo, M.R. | | 登録日 | 2022-10-17 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8ETE
 | | Bile Salt Hydrolase from B. longum with covalent inhibitor bound | | 分子名称: | (5R)-1-fluoro-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]hexan-2-one (non-preferred name), Conjugated bile acid hydrolase | | 著者 | Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-10-17 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8ESL
 | | Bile Salt Hydrolase from a Bacteroidales species with covalent inhibitor bound | | 分子名称: | (1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-1-[(2R)-6-fluoro-5-oxohexan-2-yl]-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl hydrogen sulfate (non-preferred name), Choloylglycine hydrolase | | 著者 | Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-10-14 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8EWT
 | | Bile salt hydrolase A from Lactobacillus gasseri bound to covalent probe | | 分子名称: | (5R)-5-{(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-9a,11a-dimethyl-7-[(prop-2-yn-1-yl)oxy]hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}-1-fluorohexan-2-one (non-preferred name), Conjugated bile salt hydrolase, SODIUM ION | | 著者 | Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-10-24 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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7SVE
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7SVK
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7SVF
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7SVH
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7SVG
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7SVI
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7SVJ
 | | Bile Salt Hydrolase from Lactobacillus ingluviei | | 分子名称: | CALCIUM ION, Choloylglycine hydrolase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Walker, M.E, Patel, S, Redinbo, M.R. | | 登録日 | 2021-11-19 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.
Nat Microbiol, 8, 2023
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7KGZ
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8FAO
 | | Bile Salt Hydrolase B from Lactobacillus gasseri with covalent inhibitor bound | | 分子名称: | (5R)-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-1-fluorohexan-2-one (non-preferred name), Choloylglycine hydrolase, NICKEL (II) ION | | 著者 | Grundy, M.K, Walker, M.E, Redinbo, M.R. | | 登録日 | 2022-11-28 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity
To Be Published
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8GET
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8GEO
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8GER
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7KGY
 | | Beta-glucuronidase from Faecalibacterium prausnitzii bound to the inhibitor UNC10201652-glucuronide | | 分子名称: | 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase, GLYCEROL | | 著者 | Simpson, J.B, Redinbo, M.R. | | 登録日 | 2020-10-19 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract.
Nat Commun, 13, 2022
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