8ETE

Bile Salt Hydrolase from B. longum with covalent inhibitor bound

Summary for 8ETE

• Entry DOI: 10.2210/pdb8ete/pdb
• Descriptor: Conjugated bile acid hydrolase, (5R)-1-fluoro-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]hexan-2-one (non-preferred name) (2 entities in total)
• Functional Keywords: bile salt hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bifidobacterium longum
• Total number of polymer chains: 2
• Total formula weight: 71157.13

Authors

Walker, M.E.,Redinbo, M.R. (deposition date: 2022-10-17, release date: 2023-11-01)

• Primary citation: Walker, M.E.,Redinbo, M.R.; Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)