3EAK
 
 | | NbBCII10 humanized (FGLA mutant) | | 分子名称: | NbBCII10-FGLA, SULFATE ION | | 著者 | Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | | 登録日 | 2008-08-26 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.
J.Biol.Chem., 2008
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3DWT
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3EBA
 | | CAbHul6 FGLW mutant (humanized) in complex with human lysozyme | | 分子名称: | CAbHul6, Lysozyme C, SULFATE ION | | 著者 | Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | | 登録日 | 2008-08-27 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
J.Biol.Chem., 284, 2009
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8PE1
 | | Crystal structure of Gel4 in complex with Nanobody 4 | | 分子名称: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ... | | 著者 | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | | 登録日 | 2023-06-13 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8PE2
 | | Crystal structure of Gel4 in complex with Nanobody 3 | | 分子名称: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ... | | 著者 | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | | 登録日 | 2023-06-13 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
Angew.Chem.Int.Ed.Engl., 63, 2024
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1YC7
 | | cAbAn33 VHH fragment against VSG | | 分子名称: | SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | 登録日 | 2004-12-22 | | 公開日 | 2005-06-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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1YC8
 | | cAbAn33- Y37V/E44G/R45L triple mutant | | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | 登録日 | 2004-12-22 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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1YZZ
 | | Humanized caban33 at room temperature | | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Decanniere, K, Muyldermans, S, Loris, R. | | 登録日 | 2005-03-01 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.
J.Mol.Biol., 350, 2005
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5M7Q
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4C59
 | | Structure of GAK kinase in complex with nanobody (NbGAK_4) | | 分子名称: | (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cyclin-G-associated kinase, NANOBODY | | 著者 | Chaikuad, A, Keates, T, Allerston, C.K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S. | | 登録日 | 2013-09-10 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Biochem. J., 459, 2014
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4C58
 | | Structure of GAK kinase in complex with nanobody (NbGAK_4) | | 分子名称: | 1,2-ETHANEDIOL, 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Cyclin-G-associated kinase, ... | | 著者 | Chaikuad, A, Keates, T, Allerston, C.K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S. | | 登録日 | 2013-09-10 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Biochem. J., 459, 2014
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4C57
 | | Structure of GAK kinase in complex with a nanobody | | 分子名称: | (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, 1,2-ETHANEDIOL, Cyclin-G-associated kinase, ... | | 著者 | Chaikuad, A, Keates, T, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S. | | 登録日 | 2013-09-10 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure of Cyclin G-Associated Kinase (Gak) Trapped in Different Conformations Using Nanobodies.
Biochem.J., 459, 2014
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