1YC8

cAbAn33- Y37V/E44G/R45L triple mutant

Summary for 1YC8

• Entry DOI: 10.2210/pdb1yc8/pdb
• Related: 1YC7
• Descriptor: anti-VSG immunoglobulin heavy chain variable domain cAbAn33 (2 entities in total)
• Functional Keywords: antibody, camel antibody, immune system
• Biological source: Camelus dromedarius (Arabian camel)
• Total number of polymer chains: 2
• Total formula weight: 27230.08

Authors

Conrath, K.,Vincke, C.,Stijlemans, B.,Schymkowitz, J.,Wyns, L.,Muyldermans, S.,Loris, R. (deposition date: 2004-12-22, release date: 2005-06-14, Last modification date: 2023-08-23)

• Primary citation: Conrath, K.,Vincke, C.,Stijlemans, B.,Schymkowitz, J.,Decanniere, K.,Wyns, L.,Muyldermans, S.,Loris, R.; Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.; J.Mol.Biol., 350:112-125, 2005; PubMed: 15913651; DOI: 10.1016/j.jmb.2005.04.050

Experimental method

X-RAY DIFFRACTION (2.7 Å)