1YZZ

Humanized caban33 at room temperature

Summary for 1YZZ

Entry DOI	10.2210/pdb1yzz/pdb
Related	1YC7 1YC8
Descriptor	anti-VSG immunoglobulin heavy chain variable domain cAbAn33 (2 entities in total)
Functional Keywords	antibody, camel antibody, humanization, unknown function
Biological source	Camelus dromedarius (Arabian camel)
Total number of polymer chains	2
Total formula weight	27230.08
Authors	Conrath, K.,Vincke, C.,Stijlemans, B.,Schymkowitz, J.,Decanniere, K.,Muyldermans, S.,Loris, R. (deposition date: 2005-03-01, release date: 2005-06-14, Last modification date: 2023-08-23)
Primary citation	Conrath, K.,Vincke, C.,Stijlemans, B.,Schymkowitz, J.,Decanniere, K.,Wyns, L.,Muyldermans, S.,Loris, R. Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. J.Mol.Biol., 350:112-125, 2005 Cited by PubMed: 15913651 DOI: 10.1016/j.jmb.2005.04.050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation